M. Silinski

Brain-Permeable Small-Molecule Inhibitors of Hsp90 Prevent α-Synuclein Oligomer Formation and Rescue α-Synuclein-Induced Toxicity

Carol D. Hicks, B. Hyman, J. Veal, 2010, Journal of Pharmacology and Experimental Therapeutics.

SNX2112, a Synthetic Heat Shock Protein 90 Inhibitor, Has Potent Antitumor Activity against HER Kinase–Dependent Cancers

Sarat Chandarlapaty, Neal Rosen, David B. Solit, 2008, Clinical Cancer Research.

Small molecule inhibitors of Hsp90 potently affect inflammatory disease pathways and exhibit activity in models of rheumatoid arthritis.

Laura G. Dubois, J. Veal, P. Fadden, 2008, Arthritis and rheumatism.

Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents.

Laura G. Dubois, Philip F. Hughes, J. Strachan, 2009, Journal of Medicinal Chemistry.

Application of chemoproteomics to drug discovery: identification of a clinical candidate targeting hsp90.

Briana Foley, Laura G. Dubois, Philip F. Hughes, 2010, Chemistry & biology.

Discovery of novel aminoquinazolin-7-yl 6,7-dihydro-indol-4-ones as potent, selective inhibitors of heat shock protein 90.

Philip F. Hughes, J. Veal, S. Hall, 2012, Bioorganic & medicinal chemistry letters.