Shinichiro Nakada

发表

Telomerase reverse transcriptase protects ATM-deficient hematopoietic stem cells from ROS-induced apoptosis through a telomere-independent mechanism.

T. Suda, F. Arai, K. Takubo, 2011, Blood.

T315I mutation of BCR-ABL1 into human Philadelphia chromosome-positive leukemia cell lines by homologous recombination using the CRISPR/Cas9 system

K. Goi, S. Nakada, T. Inukai, 2018, Scientific Reports.

BRCA1 Directs the Repair Pathway to Homologous Recombination by Promoting 53BP1 Dephosphorylation.

Hiro Sato, Yukari Yoshida, Takashi Nakano, 2017, Cell reports.

Opposing roles of RNF8/RNF168 and deubiquitinating enzymes in ubiquitination-dependent DNA double-strand break response signaling and DNA-repair pathway choice

S. Nakada, Shinichiro Nakada, 2016, Journal of radiation research.

Fine-tuning of DNA damage-dependent ubiquitination by OTUB2 supports the DNA repair pathway choice.

H. Ogiwara, A. Ui, Kiyoko Kato, 2014, Molecular cell.

Structural insights into two distinct binding modules for Lys63-linked polyubiquitin chains in RNF168

S. Fukai, S. Nakada, A. Yamagata, 2018, Nature Communications.

RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1.

K. Matsuo, Rikako Miyamoto Yonamine, Shinichiro Nakada, 2012, Cancer research.

Molecular and Cellular Pathobiology RNF 8 Regulates Assembly of RAD 51 at DNA Double-Strand Breaks in the Absence of BRCA 1 and 53 BP 1

K. Matsuo, S. Nakada, Rikako Miyamoto Yonamine, 2012 .

Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1

A. Gingras, D. Durocher, Lara O'Donnell, 2010, Nature.

The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage

Edward S. Miller, D. Durocher, Nadine Kolas, 2009, Cell.

Orchestration of the DNA-Damage Response by the RNF8 Ubiquitin Ligase

Laurence Pelletier, Stephen P. Jackson, Timothy M. Thomson, 2007, Science.

Abnormalities in DNA double-strand break response beyond primary immunodeficiency

Shinichiro Nakada, 2011, International journal of hematology.

BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II–DNA complexes

Hisashi Tanaka, A. Cherniack, J. Itou, 2018, Proceedings of the National Academy of Sciences.

RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination.

H. Kurumizaka, Koichi Sato, D. Schindler, 2017, Molecular cell.

RFWD 3-Mediated Ubiquiti nation Promotes Timely Removal of Both RPA and RAD 51 from DNA Damage Sites to Facilitate Homologous Recombination Graphical

H. Kurumizaka, Koichi Sato, D. Schindler, 2022 .

UBC13-Mediated Ubiquitin Signaling Promotes Removal of Blocking Adducts from DNA Double-Strand Breaks

A. Shibata, K. Hirota, Masato T. Kanemaki, 2020, iScience.

Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair

A. Shibata, K. Miyagawa, M. Yamauchi, 2018, Cell.

Early‐ and long‐term outcomes of liver transplantation with rescue allocation grafts

H. Baba, S. Nakada, E. Vibert, 2020, Clinical transplantation.

Early G2/M checkpoint failure as a molecular mechanism underlying etoposide-induced chromosomal aberrations.

J. Inazawa, M. Nagasawa, S. Mizutani, 2005, The Journal of clinical investigation.

Inducing multiple nicks promotes interhomolog homologous recombination to correct heterozygous mutations in somatic cells

Y. Nakazawa, T. Ogi, Mayuko Shimada, 2023, Nature communications.

Digenic mutations in ALDH2 and ADH5 impair formaldehyde clearance and cause a multisystem disorder, AMeD syndrome

M. Nagasaki, K. Matsuo, F. Matsuda, 2020, Science advances.

Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair

A. Masuda, K. Ohno, Yasuyoshi Oka, 2020, Cell.

Precise and efficient nucleotide substitution near genomic nick via noncanonical homology-directed repair

S. Nakada, Kazuhiro Nakajima, Yue Zhou, 2018, Genome research.

Structural Basis for Ubiquitin Recognition by Ubiquitin-Binding Zinc Finger of FAAP20

S. Fukai, S. Nakada, A. Yamagata, 2015, PloS one.

Rad18 and Rnf8 facilitate homologous recombination by two distinct mechanisms, promoting Rad51 focus formation and suppressing the toxic effect of nonhomologous end joining

S. Era, Y. Kasaishi, Shinichiro Nakada, 2014, Oncogene.

Novel polyubiquitin imaging system, PolyUb-FC, reveals that K33-linked polyubiquitin is recruited by SQSTM1/p62

Tetsuya Nakamura, S. Oshima, K. Tsuchiya, 2018, Autophagy.

Cell Cycle (231 articles)

M. Nakanishi, M. Ohki, Y. Taya, 2003 .

PP4 is a γH2AX phosphatase required for recovery from the DNA damage checkpoint

A. Gingras, D. Durocher, Ginny I. Chen, 2008, EMBO reports.

A Screen for Suppressors of Gross Chromosomal Rearrangements Identifies a Conserved Role for PLP in Preventing DNA Lesions

D. Durocher, D. C. Cabelof, Frédéric D. Sweeney, 2007, PLoS genetics.

Caffeine yields aneuploidy through asymmetrical cell division caused by misalignment of chromosomes

J. Inazawa, M. Nagasawa, S. Mizutani, 2008, Cancer science.

RNF168 E3 ligase participates in ubiquitin signaling and recruitment of SLX4 during DNA crosslink repair

T. Ohta, H. van Attikum, M. Takata, 2021, Cell reports.

Molecular Basis of Lys-63-linked Polyubiquitination Inhibition by the Interaction between Human Deubiquitinating Enzyme OTUB1 and Ubiquitin-conjugating Enzyme UBC13*

S. Fukai, S. Nakada, A. Yamagata, 2012, The Journal of Biological Chemistry.

CRISPR-Cas3 induces broad and unidirectional genome editing in human cells

H. Morisaka, Takashi Yamamoto, T. Mashimo, 2019, Nature Communications.

RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1.

K. Matsuo, S. Nakada, Rikako Miyamoto Yonamine, 2012, Cancer Research.