S. Shaik

发表

Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signaling to suppress tumorigenesis

S. Gygi, J. Blenis, B. Su, 2013, Nature Cell Biology.

Novel Insights into the Molecular Mechanisms Governing Mdm2 Ubiquitination and Destruction

Wenyi Wei, H. Inuzuka, Shavali Shaik, 2010, Oncotarget.

Systems Biology Approaches in Breast Cancer Studies

Wenyi Wei, H. Inuzuka, Shavali Shaik, 2013 .

An evolving role for DEPTOR in tumor development and progression.

Zhiwei Wang, F. Sarkar, Wenyi Wei, 2012, Neoplasia.

REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature

J. Fangusaro, Shavali Shaik, J. Nazarian, 2017, Oncotarget.

SCFFBW 7 regulates cellular apoptosis by targeting MCL 1 for ubiquitylation and destruction

Yonghong Xiao, Andrew L. Kung, Steven P. Gygi, 2011 .

Sin1 Phosphorylation Impairs Mtorc2 Complex Integrity and Inhibits Downstream Akt Signaling to Suppress Tumorigenesis Sin1 Phosphorylation Impairs Mtorc2 Complex Integrity and Inhibits Downstream Akt Signaling to Suppress Tumorigenesis Nih Public Access Author Manuscript Introduction

S. Gygi, J. Blenis, Wenyi Wei, 2022 .

Mcl-1 Ubiquitination and Destruction

Wenyi Wei, Pengda Liu, H. Inuzuka, 2011, Oncotarget.

Endothelium Aging and Vascular Diseases

Zhiwei Wang, Wenyi Wei, Pengda Liu, 2013 .

Transcriptional repressor REST drives lineage stage–specific chromatin compaction at Ptch1 and increases AKT activation in a mouse model of medulloblastoma

S. Khatua, T. MacDonald, C. Hawkins, 2019, Science Signaling.

Acetylation-Dependent Regulation of Skp2 Function

S. Gygi, P. Pandolfi, Zhiwei Wang, 2012, Cell.

SCFβ-TRCP targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration

Zhiwei Wang, Wenyi Wei, A. Tron, 2013, Oncotarget.

SCFFbw7 Regulates Cellular Apoptosis By Targeting Mcl-1 for Ubiquitination and Destruction

S. Gygi, Yonghong Xiao, R. DePinho, 2010, Nature.

Targeting the ubiquitin pathway for cancer treatment.

Zhiwei Wang, Wenyi Wei, Xiu-xia Zhou, 2015, Biochimica et biophysica acta.

APC(Cdc20) suppresses apoptosis through targeting Bim for ubiquitination and destruction.

A. Letai, M. Kirschner, Guoan Chen, 2014, Developmental cell.

Cross-Talk Between Histone Methyltransferases and Demethylases Regulate REST Transcription During Neurogenesis

A. Harmanci, Shavali Shaik, Lei Guo, 2022, Frontiers in Oncology.

SCFβ-TRCP suppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2

W. Goessling, C. Nucera, Wenyi Wei, 2012, The Journal of experimental medicine.

Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1.

Wenyi Wei, Weiguo Zou, L. Glimcher, 2011, Molecular cell.

mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.

S. Gygi, A. Toker, L. Cantley, 2011, Molecular cell.

Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase.

J. Decaprio, Wenyi Wei, Xiao Zhen Zhou, 2012, Molecular cell.

SCF(Fbw7) modulates the NFkB signaling pathway by targeting NFkB2 for ubiquitination and destruction.

S. Gygi, Akinobu Matsumoto, Wenyi Wei, 2012, Cell reports.

Cyclin C is a haploinsufficient tumour suppressor

Na Li, Iannis Aifantis, Jon C. Aster, 2014, Nature Cell Biology.

Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase.

S. Gygi, W. Kaelin, J. Harper, 2010, Cancer cell.

REST promotes ETS1‐dependent vascular growth in medulloblastoma

A. Harmanci, Feng Wang, Shavali Shaik, 2021, Molecular oncology.

Emerging roles of the FBW7 tumour suppressor in stem cell differentiation

Zhiwei Wang, F. Sarkar, Wenyi Wei, 2012, EMBO reports.

Emerging roles of the FBW 7 tumour suppressor in stem cell differentiation

Zhiwei Wang, F. Sarkar, Wenyi Wei, 2013 .

Regulation of USP37 Expression by REST-Associated G9a-Dependent Histone Methylation

G. Sbardella, Shavali Shaik, Tara H. W. Dobson, 2017, Molecular Cancer Research.

Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction.

S. Gygi, A. Toker, J. Decaprio, 2010, Molecular cell.

Medulloblastoma: novel insights into emerging therapeutic targets

Shavali Shaik, V. Gopalakrishnan, S. Maegawa, 2021, Expert opinion on therapeutic targets.

Protein Degradation in Cell Cycle

Zhiwei Wang, Wenyi Wei, Pengda Liu, 2012 .

Sin1 Phosphorylation Impairs mTORC2 Complex Integrity and Inhibits Downstream Akt Signalling to Suppress Tumorigenesis

Lee, S. Shaik, O. Arojo, 2014 .