Tarek Z. Deeb

发表

Deficits in the activity of presynaptic γ-aminobutyric acid type B receptors contribute to altered neuronal excitability in fragile X syndrome

R. J. Mather, M. Pangalos, N. Brandon, 2017, The Journal of Biological Chemistry.

The 5‐HT3B subunit affects high‐potency inhibition of 5‐HT3 receptors by morphine

T. Deeb, D. Sharp, T. Hales, 2012, British journal of pharmacology.

L-type voltage-gated calcium channel regulation of in vitro human cortical neuronal networks

Jeremy Hall, A. Harwood, T. Deeb, 2018, Scientific Reports.

Developmental seizures and mortality result from reducing GABAA receptor α2-subunit interaction with collybistin

D. Hines, N. Brandon, S. Moss, 2018, Nature Communications.

Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway

N. Brandon, O. Engkvist, S. Moss, 2018, Journal of Lipid Research.

Cytoplasmic Relocalization of TAR DNA-Binding Protein 43 Is Not Sufficient to Reproduce Cellular Pathologies Associated with ALS In vitro

N. Brandon, S. Moss, Jayanta Mukherjee, 2017, Front. Mol. Neurosci..

Potentiating KCC2 activity is sufficient to limit the onset and severity of seizures

N. Brandon, S. Moss, T. Deeb, 2018, Proceedings of the National Academy of Sciences.

Seizing Control of KCC2: A New Therapeutic Target for Epilepsy

N. Brandon, S. Moss, T. Deeb, 2017, Trends in Neurosciences.

NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor mediated currents

S. Moss, T. Deeb, P. Davies, 2011, Nature Neuroscience.

Tonically Active GABAA Receptors in Hippocampal Pyramidal Neurons Exhibit Constitutive GABA-Independent Gating

T. Deeb, T. Hales, Tricia Henderson, 2007, Molecular Pharmacology.

R. Bürli, N. Brandon, S. Moss, 2019, Proceedings of the National Academy of Sciences.

Modulation of neuronal activity by phosphorylation of the K–Cl cotransporter KCC2

K. Kaila, S. Moss, T. Deeb, 2013, Trends in Neurosciences.

Protein kinase C-dependent phosphorylation of KCC 2 serine 940 : identification and implications for the stress response of the body

K. Kaila, S. Moss, T. Deeb, 2015 .

Disrupted Cl− homeostasis contributes to reductions in the inhibitory efficacy of diazepam during hyperexcited states

S. Moss, P. Davies, Yasuko Nakamura, 2013, The European journal of neuroscience.

Hyperpolarizing GABAergic transmission depends on KCC2 function and membrane potential

S. Moss, P. Davies, H. Lee, 2011, Channels.

Developmental Regulation of KCC2 Phosphorylation Has Long-Term Impacts on Cognitive Function

N. Brandon, S. Moss, T. Deeb, 2019, Front. Mol. Neurosci..

KCC2 activity is critical in limiting the onset and severity of status epilepticus

N. Brandon, S. Moss, T. Deeb, 2015, Proceedings of the National Academy of Sciences.

Proteomic Characterization of Inhibitory Synapses Using a Novel pHluorin-tagged γ-Aminobutyric Acid Receptor, Type A (GABAA), α2 Subunit Knock-in Mouse*

S. Moss, T. Deeb, P. Davies, 2016, The Journal of Biological Chemistry.

Proteomic Characterization of Inhibitory Synapses Using a Novel pHluorin-tagged (cid:2) -Aminobutyric Acid Receptor, Type A (GABA A ), (cid:3) 2 Subunit Knock-in Mouse

S. Moss, T. Deeb, P. Davies, 2020 .

Copper and protons directly activate the zinc-activated channel.

S. Moss, T. Deeb, P. Davies, 2016, Biochemical pharmacology.

Isolation and Characterization of Multi-Protein Complexes Enriched in the K-Cl Co-transporter 2 From Brain Plasma Membranes

J. L. Smalley, N. Brandon, S. Moss, 2020, bioRxiv.

The K-Cl co-transporter 2 is a point of convergence for multiple autism spectrum disorder and epilepsy risk gene products

J. L. Smalley, N. Brandon, S. Moss, 2020, bioRxiv.

Direct activation of KCC2 arrests benzodiazepine refractory status epilepticus and limits the subsequent neuronal injury in mice

J. L. Smalley, N. Brandon, I. Chessell, 2023, Cell reports. Medicine.

Selective Inhibition of KCC2 Leads to Hyperexcitability and Epileptiform Discharges in Hippocampal Slices and In Vivo

R. J. Mather, N. Brandon, S. Moss, 2015, The Journal of Neuroscience.

Genetically encoded impairment of neuronal KCC2 cotransporter function in human idiopathic generalized epilepsy

P. Awadalla, S. Moss, G. Rouleau, 2014, EMBO reports.

Molecular architecture of potassium chloride co-transporter KCC2

N. Brandon, S. Moss, I. Medina, 2017, Scientific Reports.

The small molecule CLP257 does not modify activity of the K+–Cl− co-transporter KCC2 but does potentiate GABAA receptor activity

R. J. Mather, N. Brandon, J. Holenz, 2017, Nature Medicine.

N-Ethylmaleimide increases KCC2 cotransporter activity by modulating transporter phosphorylation

R. Bürli, N. Brandon, S. Moss, 2017, The Journal of Biological Chemistry.

Possible alterations in GABAA receptor signaling that underlie benzodiazepine‐resistant seizures

S. Moss, T. Deeb, J. Maguire, 2012, Epilepsia.

An Asymmetric Contribution to γ-Aminobutyric Type A Receptor Function of a Conserved Lysine within TM2–3 of α1, β2, and γ2 Subunits*

T. Deeb, T. Hales, Dale P. King, 2006, Journal of Biological Chemistry.

Mechanism of KCC 2 activation by N-ethylmaleimide 1 N-ethylmaleimide increases KCC 2 activity by modulating transporter phosphorylation

R. Bürli, N. Brandon, S. Moss, 2017 .

The Minimum M3-M4 Loop Length of Neurotransmitter-activated Pentameric Receptors Is Critical for the Structural Integrity of Cytoplasmic Portals*

J. A. Peters, T. Deeb, T. Hales, 2013, The Journal of Biological Chemistry.

Inhibiting with-no-lysine kinases enhances K+/Cl- cotransporter 2 activity and limits status epilepticus.

N. Brandon, S. Moss, T. Deeb, 2021, Brain : a journal of neurology.

Estradiol modulates the efficacy of synaptic inhibition by decreasing the dwell time of GABAA receptors at inhibitory synapses

M. Pangalos, N. Brandon, S. Moss, 2017, Proceedings of the National Academy of Sciences.

Regulation of GABAARs by phosphorylation.

S. Moss, T. Deeb, Yasuko Nakamura, 2015, Advances in pharmacology.

Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formation.

M. Greenberg, J. Marto, S. Moss, 2011, Developmental cell.