Lin Chen

发表

Intrarenal 1-methoxypyrene, an aryl hydrocarbon receptor agonist, mediates progressive tubulointerstitial fibrosis in mice

Yan Guo, N. Vaziri, Hua Miao, 2022, Acta Pharmacologica Sinica.

Central role of dysregulation of TGF-β/Smad in CKD progression and potential targets of its treatment.

N. Vaziri, Ying-yong Zhao, Hua Chen, 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Microbiome–metabolome reveals the contribution of gut–kidney axis on kidney disease

Yan Guo, N. Vaziri, Ying-yong Zhao, 2019, Journal of Translational Medicine.

Dietary natural flavonoids treating cancer by targeting aryl hydrocarbon receptor

N. Vaziri, Ying-yong Zhao, Ya-long Feng, 2019, Critical reviews in toxicology.

Combined Clinical Phenotype and Lipidomic Analysis Reveals the Impact of Chronic Kidney Disease on Lipid Metabolism.

N. Vaziri, Ying-yong Zhao, Hua Chen, 2017, Journal of proteome research.

The link between phenotype and fatty acid metabolism in advanced chronic kidney disease

Ming Wang, N. Vaziri, Ying-yong Zhao, 2017, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Title The link between phenotype and fatty acid metabolism in advanced chronic kidney disease Permalink

N. Vaziri, Mingwang, Ying-yong Zhao, 2017 .

Aryl hydrocarbon receptor activation mediates kidney disease and renal cell carcinoma

Yan Guo, N. Vaziri, Ying-yong Zhao, 2019, Journal of Translational Medicine.

Proteomics for Biomarker Identification and Clinical Application in Kidney Disease.

Ming Wang, Yan Guo, Ying-yong Zhao, 2018, Advances in clinical chemistry.

Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan

Ming Wang, D. Samuels, Hui Yu, 2019, Nature Communications.

Metabolomic application in toxicity evaluation and toxicological biomarker identification of natural product.

Ying-yong Zhao, Hua Miao, Hua Chen, 2016, Chemico-biological interactions.

Microbiome–metabolomics reveals gut microbiota associated with glycine-conjugated metabolites and polyamine metabolism in chronic kidney disease

Ming Wang, Yan Guo, N. Vaziri, 2019, Cellular and Molecular Life Sciences.

Poricoic acid A activates AMPK to attenuate fibroblast activation and abnormal extracellular matrix remodelling in renal fibrosis.

N. Vaziri, Ying-yong Zhao, Dan-Qian Chen, 2020, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy.

Ming Wang, N. Vaziri, Ying-yong Zhao, 2017, Chemico-biological interactions.

Poricoic acid A as a modulator of TPH-1 expression inhibits renal fibrosis via modulating protein stability of β-catenin and β-catenin-mediated transcription

Ying-yong Zhao, Dan-Qian Chen, Lin X. Chen, 2020, Therapeutic advances in chronic disease.

Alisol B 23-acetate attenuates CKD progression by regulating the renin–angiotensin system and gut–kidney axis

N. Vaziri, Ying-yong Zhao, Hua Miao, 2020, Therapeutic advances in chronic disease.

Redox signaling in aging kidney and opportunity for therapeutic intervention through natural products.

N. Vaziri, Ying-yong Zhao, Shuangcheng Ma, 2019, Free radical biology & medicine.

Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis.

Ming Wang, N. Vaziri, Ying-yong Zhao, 2019, Free radical biology & medicine.

The Matrix Metalloproteinase-13 Inhibitor Poricoic Acid ZI Ameliorates Renal Fibrosis by Mitigating Epithelial-Mesenchymal Transition.

Ming Wang, N. Vaziri, S. Zhuang, 2019, Molecular nutrition & food research.

Unilateral ureteral obstruction causes gut microbial dysbiosis and metabolome disorders contributing to tubulointerstitial fibrosis

Yan Guo, N. Vaziri, S. Zhuang, 2019, Experimental & Molecular Medicine.

Novel inhibitors of the cellular renin‐angiotensin system components, poricoic acids, target Smad3 phosphorylation and Wnt/β‐catenin pathway against renal fibrosis

Ming Wang, Yan Guo, N. Vaziri, 2018, British journal of pharmacology.

An Integrated Lipidomics and Phenotype Study Reveals Protective Effect and Biochemical Mechanism of Traditionally Used Alisma orientale Juzepzuk in Chronic Kidney Disease

Ming Wang, Ying-yong Zhao, Hua Miao, 2018, Front. Pharmacol..

Poricoic acid ZA, a novel RAS inhibitor, attenuates tubulo-interstitial fibrosis and podocyte injury by inhibiting TGF-β/Smad signaling pathway.

Ming Wang, Ying-yong Zhao, Hua Chen, 2017, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Small molecules from natural products targeting the Wnt/β-catenin pathway as a therapeutic strategy.

N. Vaziri, Ying-yong Zhao, Shuangcheng Ma, 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Combined melatonin and poricoic acid A inhibits renal fibrosis through modulating the interaction of Smad3 and β-catenin pathway in AKI-to-CKD continuum

Ming Wang, Yan Guo, N. Vaziri, 2019, Therapeutic advances in chronic disease.

Metabolomics highlights pharmacological bioactivity and biochemical mechanism of traditional Chinese medicine.

Ming Wang, Ying-yong Zhao, Hua Chen, 2017, Chemico-biological interactions.

Novel poricoic acids attenuate renal fibrosis through regulating redox signalling and aryl hydrocarbon receptor activation.

Ming Wang, Ying-yong Zhao, Lin X. Chen, 2020, Phytomedicine : international journal of phytotherapy and phytopharmacology.

1‐Hydroxypyrene mediates renal fibrosis through aryl hydrocarbon receptor signalling pathway

Yan Guo, N. Vaziri, S. Zhuang, 2021, British journal of pharmacology.

Identification of endogenous 1‐aminopyrene as a novel mediator of progressive chronic kidney disease via aryl hydrocarbon receptor activation

Yan Guo, N. Vaziri, S. Zhuang, 2020, British journal of pharmacology.

Title Role of RAS / Wnt / beta-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy

Ming Wang, N. Vaziri, Ying-yong Zhao, 2017 .

Role of RAS/Wnt/ b -catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy Chemico-Biological Interactions

Ming Wang, N. Vaziri, Hua Chen, 2017 .

Novel RAS Inhibitors Poricoic Acid ZG and Poricoic Acid ZH Attenuate Renal Fibrosis via a Wnt/β-Catenin Pathway and Targeted Phosphorylation of smad3 Signaling.

Ming Wang, Yan Guo, N. Vaziri, 2018, Journal of agricultural and food chemistry.