Yang Xiang

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Impact of whole‐body versus nose‐only inhalation exposure systems on systemic, respiratory, and cardiovascular endpoints in a 2‐month cigarette smoke exposure study in the ApoE−/− mouse model

M. Peitsch, J. Hoeng, B. Titz, 2021, Journal of applied toxicology : JAT.

A 6-month systems toxicology inhalation study in ApoE-/- mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared to cigarette smoke.

M. Peitsch, Ashutosh Kumar, A. Sewer, 2020, American journal of physiology. Heart and circulatory physiology.

A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. II. Systems toxicology assessment.

Rémi H. J. Dulize, M. Peitsch, J. Hoeng, 2018, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Toxicity of the main electronic cigarette components, propylene glycol, glycerin, and nicotine, in Sprague-Dawley rats in a 90-day OECD inhalation study complemented by molecular endpoints.

M. Peitsch, J. Hoeng, Davide Sciuscio, 2017, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models

Yang Xiang, Manuel C. Peitsch, Julia Hoeng, 2014, BMC Bioinformatics.

Human bronchial epithelial cells exposed in vitro to cigarette smoke at the air-liquid interface resemble bronchial epithelium from human smokers.

M. Peitsch, V. Belcastro, A. Sewer, 2013, American journal of physiology. Lung cellular and molecular physiology.

bronchial epithelium from human smokers cigarette smoke at the air-liquid interface resemble Human bronchial epithelial cells exposed in vitro to

M. Peitsch, V. Belcastro, A. Sewer, 2013 .

Divergence Weighted Independence Graphs for the Exploratory Analysis of Biological Expression Data

Yang Xiang, Manuel C. Peitsch, Joe Whittaker, 2013 .

A 7-month inhalation toxicology study in C57BL/6 mice demonstrates reduced pulmonary inflammation and emphysematous changes following smoking cessation or switching to e-vapor products

M. Peitsch, Ashutosh Kumar, J. Hoeng, 2021, Toxicology Research and Application.

Evaluation of the Tobacco Heating System 2.2. Part 4: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects compared with cigarette smoke.

Julia Hoeng, Emilija Veljkovic, Manuel C Peitsch, 2016, Regulatory toxicology and pharmacology : RTP.

Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models

M. Peitsch, A. Sewer, J. Hoeng, 2014, BMC Bioinformatics.

The sbv IMPROVER Systems Toxicology Computational Challenge: Identification of Human and Species-Independent Blood Response Markers as Predictors of Smoking Exposure and Cessation Status.

Carine Poussin, Julia Hoeng, Stéphanie Boué, 2017, Computational toxicology.

Biological impact of cigarette smoke compared to an aerosol produced from a prototypic modified risk tobacco product on normal human bronchial epithelial cells.

M. Peitsch, J. Hoeng, F. Martin, 2015, Toxicology in vitro : an international journal published in association with BIBRA.

Evaluation of the Tobacco Heating System 2.2 (THS2.2). Part 5: microRNA expression from a 90-day rat inhalation study indicates that exposure to THS2.2 aerosol causes reduced effects on lung tissue compared with cigarette smoke.

M. Peitsch, A. Sewer, J. Hoeng, 2016, Regulatory toxicology and pharmacology : RTP.

Systems toxicology approaches enable mechanistic comparison of spontaneous and cigarette smoke-related lung tumor development in the A/J mouse model

M. Peitsch, A. Sewer, K. Luettich, 2014, Interdisciplinary toxicology.

The Response of Human Nasal and Bronchial Organotypic Tissue Cultures to Repeated Whole Cigarette Smoke Exposure

Marcel Geertz, Julia Hoeng, Carole Mathis, 2014, International journal of toxicology.

Impact Assessment of Cigarette Smoke Exposure on Organotypic Bronchial Epithelial Tissue Cultures: A Comparison of Mono-Culture and Coculture Model Containing Fibroblasts

Manuel C. Peitsch, Julia Hoeng, Carole Mathis, 2015, Toxicological sciences : an official journal of the Society of Toxicology.

A 28-day rat inhalation study with an integrated molecular toxicology endpoint demonstrates reduced exposure effects for a prototypic modified risk tobacco product compared with conventional cigarettes.

Julia Hoeng, Stephan Gebel, Manuel C Peitsch, 2014, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Discriminating Spontaneous From Cigarette Smoke and THS 2.2 Aerosol Exposure-Related Proliferative Lung Lesions in A/J Mice by Using Gene Expression and Mutation Spectrum Data

Rémi H. J. Dulize, M. Peitsch, K. Luettich, 2021, Frontiers in Toxicology.

In vitro systems toxicology approach to investigate the effects of repeated cigarette smoke exposure on human buccal and gingival organotypic epithelial tissue cultures

Manuel C. Peitsch, Marcel Geertz, Julia Hoeng, 2014, Toxicology mechanisms and methods.

A framework for in vitro systems toxicology assessment of e-liquids

Manuel C. Peitsch, Julia Hoeng, Carole Mathis, 2016, Toxicology mechanisms and methods.

A lower impact of an acute exposure to electronic cigarette aerosols than to cigarette smoke in human organotypic buccal and small airway cultures was demonstrated using systems toxicology assessment

M. Peitsch, J. Hoeng, E. Guedj, 2019, Internal and Emergency Medicine.

A systems toxicology approach for comparative assessment: Biological impact of an aerosol from a candidate modified-risk tobacco product and cigarette smoke on human organotypic bronchial epithelial cultures.

Ashraf Elamin, Julia Hoeng, Carole Mathis, 2017, Toxicology in vitro : an international journal published in association with BIBRA.

sbv IMPROVER Diagnostic Signature Challenge

Yang Xiang, Erhan Bilal, Pablo Meyer, 2013 .

In vitro testing of salt coating of fabrics as a potential antiviral agent in reusable face masks

M. Peitsch, J. Hoeng, S. Lebrun, 2022, Scientific Reports.

Towards the validation of a lung tumorigenesis model with mainstream cigarette smoke inhalation using the A/J mouse.

S. Gebel, H. Haussmann, Y. Xiang, 2013, Toxicology.