L. Darragh

发表

Overcoming Resistance to Combination Radiation-Immunotherapy: A Focus on Contributing Pathways Within the Tumor Microenvironment

S. Karam, Laurel B. Darragh, A. Oweida, 2019, Front. Immunol..

Simultaneous targeting of PD-1 and IL-2Rβγ with radiation therapy inhibits pancreatic cancer growth and metastasis.

S. Karam, Molishree Joshi, Nicholas A. Olimpo, 2023, Cancer cell.

Induction of ADAM10 by Radiation Therapy Drives Fibrosis, Resistance, and Epithelial-to-Mesenchyal Transition in Pancreatic Cancer

Kimberly R. Jordan, L. Mestroni, M. McCarter, 2021, Cancer Research.

Resistance to Radiotherapy and PD-L1 Blockade Is Mediated by TIM-3 Upregulation and Regulatory T-Cell Infiltration

S. Karam, A. Tan, D. Raben, 2018, Clinical Cancer Research.

Elective nodal irradiation mitigates local and systemic immunity generated by combination radiation and immunotherapy in head and neck tumors

S. Karam, S. Dow, Molishree Joshi, 2022, Nature Communications.

Toll-like receptors TLR2 and TLR4 block the replication of pancreatic β cells in diet-induced obesity

R. Kulkarni, S. Kersten, Bethany A. Carboneau, 2019, Nature Immunology.

Title: Targeting Treg-expressed STAT3 enhances NK-mediated surveillance of metastasis and improves therapeutic response in pancreatic adenocarcinoma and dependent surveillance of in

Laurel, K. Goodman, S. Karam, 2021 .

Inhibition of EphB4-Ephrin-B2 Signaling Reprograms the Tumor Immune Microenvironment in Head and Neck Cancers.

A. Jimeno, S. Karam, D. Raben, 2019, Cancer research.

A phase I/Ib trial and biological correlate analysis of neoadjuvant SBRT with single-dose durvalumab in HPV-unrelated locally advanced HNSCC

Kimberly R. Jordan, A. Jimeno, S. Karam, 2022, Nature Cancer.

Targeting resistance to radiation-immunotherapy in cold HNSCCs by modulating the Treg-dendritic cell axis

D. G. Osborne, S. Karam, E. Chan, 2021, Journal for ImmunoTherapy of Cancer.

Amateur antigen‐presenting cells in the tumor microenvironment

S. Karam, Laurel B. Darragh, L. Darragh, 2021, Molecular carcinogenesis.

Complement C3a and C5a receptor blockade modulates regulatory T cell conversion in head and neck cancer

S. Karam, E. Kleczko, R. Nemenoff, 2021, Journal for ImmunoTherapy of Cancer.

EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment

S. Karam, R. Ferris, Olga C. Rodriguez, 2022, Nature Communications.

Selective targeting of IL2Rβγ combined with radiotherapy triggers CD8- and NK-mediated immunity, abrogating metastasis in HNSCC

S. Karam, P. Umaña, Christian Klein, 2023, Cell reports. Medicine.

Cancer immunotherapy responses persist after lymph node resection

M. V. Vander Heiden, G. Boland, L. Munn, 2023, bioRxiv.

Sensory nerve release of CGRP increases tumor growth in HNSCC by suppressing TILs.

A. van Bokhoven, Molishree Joshi, Nicholas A. Olimpo, 2024, Med.

STAT3 Modulation of Regulatory T Cells in Response to Radiation Therapy in Head and Neck Cancer.

S. Karam, D. Raben, L. Heasley, 2019, Journal of the National Cancer Institute.

Pancreatic Tumor Microenvironment Modulation by EphB4-ephrinB2 Inhibition and Radiation Combination

Kimberly R. Jordan, K. Goodman, S. Karam, 2019, Clinical Cancer Research.

FLT3L Release by Natural Killer Cells Enhances Response to Radioimmunotherapy in Preclinical Models of HNSCC

S. Karam, L. Lenz, E. Clambey, 2021, Clinical Cancer Research.

Loss of cancer cell STAT1 improves response to radiation therapy and promotes T cell activation in head and neck squamous cell carcinoma

S. Karam, Laurel B. Darragh, A. Oweida, 2021, Cancer Immunology, Immunotherapy.