Chris Gaiteri

发表

Multi-omic Directed Networks Describe Features of Gene Regulation in Aged Brains and Expand the Set of Genes Driving Cognitive Decline

David A. Bennett, Sara Mostafavi, Lei Yu, 2018, Front. Genet..

Finding the pathology of major depression through effects on gene interaction networks

C. Gaiteri, Chris Gaiteri, 2011 .

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

L. Tran, Bin Zhang, C. Gaiteri, 2013, Cell.

APOE ε2ε4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults

C. Gaiteri, D. Bennett, J. Farfel, 2018, Neurology.

Meta-Analysis of the Alzheimer’s Disease Human Brain Transcriptome and Functional Dissection in Mouse Models

James A. Eddy, Benjamin A. Logsdon, Cory C. Funk, 2020, Cell reports.

APOE genotypes as a risk factor for age-dependent accumulation of cerebrovascular disease in older adults

C. Gaiteri, J. Farfel, M. Lamar, 2018, Alzheimer's & Dementia.

Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease

Jason J. Corneveaux, C. Gaiteri, A. Myers, 2013, Neurobiology of Aging.

Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level

A. Wingo, Bin Zhang, C. Gaiteri, 2021, Nature Neuroscience.

Meta-analysis of the human brain transcriptome identifies heterogeneity across human AD coexpression modules robust to sample collection and methodological approach

James A. Eddy, Benjamin A. Logsdon, Cory C. Funk, 2019, bioRxiv.

Cascading epigenomic analysis for identifying disease genes from the regulatory landscape of GWAS variants

C. Gaiteri, D. Bennett, S. Mostafavi, 2021, bioRxiv.

The Molecular and Neuropathological Consequences of Genetic Risk for Alzheimer's Dementia

C. Gaiteri, D. Bennett, S. Mostafavi, 2018, Front. Neurosci..

Genetic variants in Alzheimer disease — molecular and brain network approaches

C. Gaiteri, D. Bennett, S. Mostafavi, 2016, Nature Reviews Neurology.

Association of Cortical β-Amyloid Protein in the Absence of Insoluble Deposits With Alzheimer Disease.

J. Schneider, C. Gaiteri, D. Bennett, 2019, JAMA neurology.

Seasonal plasticity of cognition and related biological measures in adults with and without Alzheimer disease: Analysis of multiple cohorts

David A Bennett, Claire Paquet, Sandra E Black, 2018, PLoS medicine.

A multi-omic atlas of the human frontal cortex for aging and Alzheimer’s disease research

Hans-Ulrich Klein, David A Bennett, Sara Mostafavi, 2018, Scientific Data.

Association of DNA methylation in the brain with age in older persons is confounded by common neuropathologies.

S. Leurgans, C. Gaiteri, D. Bennett, 2015, The international journal of biochemistry & cell biology.

Quantitative Systems Pharmacology for Neuroscience Drug Discovery and Development: Current Status, Opportunities, and Challenges

C. Gaiteri, D. Bennett, H. Geerts, 2019, CPT: pharmacometrics & systems pharmacology.

Identifying the molecular systems that influence cognitive resilience to Alzheimer's disease in genetically diverse mice

Robert W. Williams, C. Gaiteri, S. Neuner, 2020, Learning & memory.

Deep learning decodes the principles of differential gene expression

C. Gaiteri, S. Mostafavi, S. Tasaki, 2020, Nature Machine Intelligence.

Decoding differential gene expression

C. Gaiteri, S. Mostafavi, S. Tasaki, 2020, bioRxiv.

APOE ε4-TOMM40 ‘523 haplotypes and the risk of Alzheimer’s disease in older Caucasian and African Americans

A. Roses, C. Gaiteri, D. Bennett, 2017, PloS one.

TOMM40′523 variant and cognitive decline in older persons with APOE ε3/3 genotype

A. Roses, C. Gaiteri, D. Bennett, 2017, Neurology.

A multi-omic atlas of the human frontal cortex for aging and Alzheimer’s disease research

L. Mangravite, B. Vardarajan, Jishu Xu, 2018, Scientific Data.

Benchmarking of deep neural networks for predicting personal gene expression from DNA sequence highlights shortcomings

P. D. De Jager, S. Tasaki, M. Chikina, 2023, bioRxiv.

A cortical immune network map identifies distinct microglial transcriptional programs associated with β-amyloid and Tau pathologies

Charles C. White, C. Gaiteri, D. Bennett, 2021, Translational Psychiatry.

A cortical immune network map identifies a subset of human microglia involved in Tau pathology

Charles C. White, C. Gaiteri, D. Bennett, 2017, bioRxiv.

Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain

C. Gaiteri, D. Bennett, S. Mostafavi, 2018, Molecular Neurodegeneration.

An xQTL map integrates the genetic architecture of the human brain’s transcriptome and epigenome

Ellis Patrick, Bernard Ng, Hans-Ulrich Klein, 2017, Nature Neuroscience.

Differentially Expressed Genes in Major Depression Reside on the Periphery of Resilient Gene Coexpression Networks

Etienne Sibille, C. Gaiteri, E. Sibille, 2011, Front. Neurosci..

Physical activity, common brain pathologies, and cognition in community-dwelling older adults

S. Leurgans, C. Gaiteri, D. Bennett, 2019, Neurology.

Dissecting the human leptomeninges at single-cell resolution

C. Gaiteri, Jishu Xu, Sashini De Tissera, 2022, bioRxiv.

Aging the brain: multi-region methylation principal component based clock in the context of Alzheimer’s disease

M. Levine, S. Horvath, C. Gaiteri, 2022, bioRxiv.

Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors

V. Menon, C. Gaiteri, D. Bennett, 2021, Neuron.

Large‐scale deep multi‐layer analysis of Alzheimer’s disease brain reveals strong proteomic disease‐related changes not observed at the RNA level

A. Wingo, C. Gaiteri, A. Levey, 2021, Alzheimer's & dementia : the journal of the Alzheimer's Association.

The Interaction of Intrinsic Dynamics and Network Topology in Determining Network Burst Synchrony

Jonathan E. Rubin, Christopher Gaiteri, C. Gaiteri, 2011, Front. Comput. Neurosci..

Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions

Benjamin A. Logsdon, Kara H. Woo, Anna K. Greenwood, 2020, Scientific Data.

A molecular signature of depression in the amygdala.

David A Lewis, George C Tseng, Etienne Sibille, 2009, The American journal of psychiatry.

Inferring protein expression changes from mRNA in Alzheimer’s dementia using deep neural networks

C. Gaiteri, V. Petyuk, S. Tasaki, 2022, Nature Communications.

Inferring protein expression changes from mRNA in Alzheimer’s dementia using deep neural networks

C. Gaiteri, V. Petyuk, S. Tasaki, 2022, Nature Communications.

Cortical proteins may provide motor resilience in older adults

C. Gaiteri, D. Bennett, F. Grodstein, 2021, Scientific Reports.

Cognition may link cortical IGFBP5 levels with motor function in older adults

C. Gaiteri, D. Bennett, P. D. De Jager, 2019, PloS one.

Targeted brain proteomics uncover multiple pathways to Alzheimer's dementia

Sara Mostafavi, Tujin Shi, Lei Yu, 2018, Annals of neurology.

A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease

Charles C. White, A. Regev, J. Schneider, 2018, Nature Neuroscience.

Deconvolving the contributions of cell-type heterogeneity on cortical gene expression

Ellis Patrick, Bernard Ng, David A Bennett, 2019, bioRxiv.

Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline

J. Schneider, C. Gaiteri, D. Bennett, 2017, JAMA neurology.

Microstructural changes in the brain mediate the association of AK4, IGFBP5, HSPB2, and ITPK1 with cognitive decline

C. Gaiteri, D. Bennett, K. Arfanakis, 2019, Neurobiology of Aging.

A Molecular Basis of Human Brain Connectivity

C. Gaiteri, N. Seyfried, M. Cieslak, 2023, bioRxiv.

Identifying the molecular systems that influence cognitive resilience to Alzheimer's disease in genetically diverse mice

C. Kaczorowski, N. Hadad, Sarah M. Neuner, 2020, Learning & memory.

Beyond modules and hubs: the potential of gene coexpression networks for investigating molecular mechanisms of complex brain disorders

G. Tseng, C. Gaiteri, E. Sibille, 2014, Genes, brain, and behavior.

Supplemental Methods For: Identifying Robust Communities and Multi-community Nodes by Combining Top-down and Bottom-up Approaches to Clustering

Boleslaw K. Szymanski, Konstantin Kuzmin, Thomas J. Grabowski, 2022 .

Cascading epigenomic analysis for identifying disease genes from the regulatory landscape of GWAS variants

D. Bennett, S. Mostafavi, P. D. De Jager, 2019, bioRxiv.

Supporting novel biomedical research via multilayer collaboration networks

Boleslaw K. Szymanski, Partha Sarathi Mukherjee, Konstantin Kuzmin, 2016, Applied Network Science.

Bayesian Network Reconstruction Using Systems Genetics Data: Comparison of MCMC Methods

Elias Chaibub Neto, Benjamin A. Sauerwine, Bruce Hoff, 2015, Genetics.

Robust, scalable, and informative clustering for diverse biological networks

S. Tasaki, Faraz A. Sultan, A. Iatrou, 2023, Genome Biology.

Association Between Quantitative Gait and Balance Measures and Total Daily Physical Activity in Community-Dwelling Older Adults

Jeffrey M. Hausdorff, S. Leurgans, C. Gaiteri, 2018, The journals of gerontology. Series A, Biological sciences and medical sciences.

Genetic risk for Alzheimer’s dementia predicts motor deficits through multi-omic systems in older adults

C. Gaiteri, D. Bennett, P. D. De Jager, 2019, Translational Psychiatry.

Brain xQTL map: Integrating the genetic architecture of the human brain transcriptome and epigenome

C. Gaiteri, D. Bennett, S. Mostafavi, 2017, bioRxiv.

Gene expression and DNA methylation are extensively coordinated with MRI-based brain microstructural characteristics

C. Gaiteri, D. Bennett, S. Mostafavi, 2018, Brain Imaging and Behavior.

Altered Gene Synchrony Suggests a Combined Hormone-Mediated Dysregulated State in Major Depression

C. Gaiteri, D. Lewis, E. Sibille, 2010, PloS one.

Morton's foot and pyridoxal 5'-phosphate deficiency: genetically linked traits.

C. Gaiteri, T. Nichols, Chris Gaiteri, 2014, Medical hypotheses.

The molecular genetic landscape of human brain size variation

Joseph T. Glessner, J. Glessner, E. Courchesne, 2022, bioRxiv.

Using Transcriptomic Hidden Variables to Infer Context-Specific Genotype Effects in the Brain.

C. Gaiteri, D. Bennett, S. Mostafavi, 2019, American journal of human genetics.

A molecular network of the aging brain implicates INPPL1 and PLXNB1 in Alzheimer’s disease

Charles C. White, A. Regev, J. Schneider, 2017, bioRxiv.

Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology

Charles C. White, J. Schneider, C. Gaiteri, 2020, Neuron.