Andrew C Pearce

发表

SCL-mediated regulation of the cell-cycle regulator p21 is critical for murine megakaryopoiesis.

P. Vyas, D. Ferguson, S. Watson, 2011, Blood.

murine megakaryopoiesis is critical for p21 SCL-mediated regulation of the cell-cycle regulator

P. Vyas, D. Ferguson, S. Watson, 2012 .

Vav1, but not Vav2, contributes to platelet aggregation by CRP and thrombin, but neither is required for regulation of phospholipase C.

E. Vigorito, M. Turner, S. Watson, 2002, Blood.

The molecular species responsible for α1‐antitrypsin deficiency are suppressed by a small molecule chaperone

J. Irving, D. Lomas, A. Fra, 2020, The FEBS journal.

DC-SIGN and CLEC-2 Mediate Human Immunodeficiency Virus Type 1 Capture by Platelets

Gemma L. J. Fuller, J. Hoxie, S. Watson, 2006, Journal of Virology.

A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2.

Gemma L. J. Fuller, S. Watson, Ángel García, 2006, Blood.

GSK137, a potent small-molecule BCL6 inhibitor with in vivo activity, suppresses antibody responses in mice

J. Schofield, M. Convery, Xiping Zhang, 2021, The Journal of biological chemistry.

GPVI and integrin αIIbβ3 signaling in platelets

O. McCarty, S. Watson, J. Auger, 2005, Journal of thrombosis and haemostasis : JTH.

Differential proteome analysis of TRAP-activated platelets: involvement of DOK-2 and phosphorylation of RGS proteins.

R. Dwek, S. Watson, Ángel García, 2004, Blood.

Extensive analysis of the human platelet proteome by two‐dimensional gel electrophoresis and mass spectrometry

R. Dwek, S. Watson, Ángel García, 2004, Proteomics.

Rac1 Is Essential for Platelet Lamellipodia Formation and Aggregate Stability under Flow*

N. Kalia, O. McCarty, S. Watson, 2005, Journal of Biological Chemistry.

Differential roles for the adapters Gads and LAT in platelet activation by GPVI and CLEC-2

S. Watson, C. Hughes, J. Auger, 2008, Journal of thrombosis and haemostasis : JTH.

Role of the p110δ PI 3-kinase in integrin and ITAM receptor signalling in platelets

E. Vigorito, K. Okkenhaug, S. Watson, 2005, Platelets.

Imatinib attenuates hypoxia-induced pulmonary arterial hypertension pathology via reduction in 5-hydroxytryptamine through inhibition of tryptophan hydroxylase 1 expression.

I. Clay, J. Westwick, D. Rowlands, 2013, American journal of respiratory and critical care medicine.

Towards complete analysis of the platelet proteome

R. Dwek, E. O’Neill, S. Watson, 2002, Proteomics.

The C-type Lectin Receptors CLEC-2 and Dectin-1, but Not DC-SIGN, Signal via a Novel YXXL-dependent Signaling Cascade*

Gemma L. J. Fuller, S. Watson, M. Tomlinson, 2007, Journal of Biological Chemistry.

Evaluation of a crystallographic surrogate for kallikrein 5 in the discovery of novel inhibitors for Netherton syndrome.

A. Hovnanian, J. Liddle, Kathrine J. Smith, 2019, Acta crystallographica. Section F, Structural biology communications.

Impaired bone morphogenetic protein receptor II signaling in a transforming growth factor-β-dependent mouse model of pulmonary hypertension and in systemic sclerosis.

C. Denton, A. Holmes, A. Gilbane, 2015, American journal of respiratory and critical care medicine.

A role for adhesion and degranulation‐promoting adapter protein in collagen‐induced platelet activation mediated via integrin α2β1

C. Hughes, D. Bihan, R. Farndale, 2012, Journal of thrombosis and haemostasis : JTH.

Attenuation of leukocyte recruitment via CXCR1/2 inhibition stops the progression of PAH in mice with genetic ablation of endothelial BMPR-II.

D. Budd, A. Holmes, L. Ciuclan, 2011, Blood.

Renal cells activate the platelet receptor CLEC-2 through podoplanin.

S. Watson, D. Jackson, A. R. Mistry, 2008, The Biochemical journal.

Vav family proteins are required for optimal regulation of PLCγ2 by integrin αIIbβ3

E. Vigorito, O. McCarty, S. Watson, 2007 .

Vav family proteins are required for optimal regulation of PLCgamma2 by integrin alphaIIbbeta3.

E. Vigorito, M. Turner, O. McCarty, 2007, The Biochemical journal.

Design and development of a series of borocycles as selective, covalent kallikrein 5 inhibitors.

A. Hovnanian, J. Liddle, P. Thomas, 2019, Bioorganic & medicinal chemistry letters.

An inhibitor of NADPH oxidase-4 attenuates established pulmonary fibrosis in a rodent disease model.

Benjamin R Bellenie, C. Cope, N. Press, 2013, American journal of respiratory cell and molecular biology.

Vav1 and Vav3 Have Critical but Redundant Roles in Mediating Platelet Activation by Collagen*

Elena Vigorito, Martin Turner, E. Vigorito, 2004, Journal of Biological Chemistry.

Differential Roles of the PKC Novel Isoforms, PKCδ and PKCε, in Mouse and Human Platelets

S. Watson, C. Pears, C. Hughes, 2008, PloS one.

University of Birmingham G6b-B inhibits constitutive and agonist-induced signaling by glycoprotein VI and CLEC-2

S. Watson, M. Tomlinson, Y. Senis, 2008 .

G6b-B Inhibits Constitutive and Agonist-induced Signaling by Glycoprotein VI and CLEC-2*S⃞

S. Watson, M. Tomlinson, Y. Senis, 2008, Journal of Biological Chemistry.