Partha Krishnamurthy

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Editor's Highlight: Metformin Protects Against Acetaminophen Hepatotoxicity by Attenuation of Mitochondrial Oxidant Stress and Dysfunction.

H. Jaeschke, A. Ramachandran, P. Krishnamurthy, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

Dual Role of Epidermal Growth Factor Receptor in Liver Injury and Regeneration after Acetaminophen Overdose in Mice

Mitchell R. McGill, H. Jaeschke, B. Bhushan, 2017, Toxicological sciences : an official journal of the Society of Toxicology.

Impaired TFEB-Mediated Lysosome Biogenesis and Autophagy Promote Chronic Ethanol-Induced Liver Injury and Steatosis in Mice.

Xi C. He, A. Ballabio, Linheng Li, 2018, Gastroenterology.

Arsenite Effects on Mitochondrial Bioenergetics in Human and Mouse Primary Hepatocytes Follow a Nonlinear Dose Response

R. Swerdlow, P. Krishnamurthy, Kristen Mickey, 2017, Oxidative medicine and cellular longevity.

Spatiotemporal Coupling of cAMP Transporter to CFTR Chloride Channel Function in the Gut Epithelia

M. Zaccolo, J. Schuetz, K. Jalink, 2007, Cell.

Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice

R. Dobrowsky, H. Jaeschke, W. Ding, 2019, Redox biology.

Targeting the Enterohepatic Bile Acid Signaling Induces Hepatic Autophagy via a CYP7A1–AKT–mTOR Axis in Mice

J. Chiang, Tiangang Li, W. Ding, 2016, Cellular and molecular gastroenterology and hepatology.

The Stem Cell Marker Bcrp/ABCG2 Enhances Hypoxic Cell Survival through Interactions with Heme*

J. Schuetz, D. Ross, T. Nakanishi, 2004, Journal of Biological Chemistry.

Detoxification Functions of the Liver

U. Apte, P. Krishnamurthy, Partha Krishnamurthy, 2011 .

The ATP-binding cassette transporter ABCB6 is induced by arsenic and protects against arsenic cytotoxicity.

Hemantkumar Chavan, Mahitha Oruganti, Partha Krishnamurthy, 2011, Toxicological sciences : an official journal of the Society of Toxicology.

Identification of a mammalian mitochondrial porphyrin transporter

Daxi Sun, J. Schuetz, B. Sosa-Pineda, 2006, Nature.

The ABC Transporter Abcg2/Bcrp: Role in Hypoxia Mediated Survival

J. Schuetz, P. Krishnamurthy, Partha Krishnamurthy, 2005, Biometals.

Efficient Purification and Reconstitution of ATP Binding Cassette Transporter B6 (ABCB6) for Functional and Structural Studies*

G. Tegos, P. Krishnamurthy, Hemantkumar Chavan, 2013, The Journal of Biological Chemistry.

A Novel Flow Cytometric HTS Assay Reveals Functional Modulators of ATP Binding Cassette Transporter ABCB6

Tudor I. Oprea, Susan M. Young, Stephanie E. Chavez, 2012, PloS one.

Polycyclic Aromatic Hydrocarbons (PAHs) Mediate Transcriptional Activation of the ATP Binding Cassette Transporter ABCB6 Gene via the Aryl Hydrocarbon Receptor (AhR)*

P. Krishnamurthy, Hemantkumar Chavan, Partha Krishnamurthy, 2012, The Journal of Biological Chemistry.

Functional significance of the ATP‐binding cassette transporter B6 in hepatocellular carcinoma

P. Krishnamurthy, Hemantkumar Chavan, Kishore Polireddy, 2011, Molecular oncology.

Studies ( ABCB 6 ) for Functional and Structural ATP Binding Cassette Transporter B 6 Efficient Purification and Reconstitution of Membrane Biology :

Mohiuddin, G. Tegos, P. Krishnamurthy, 2013 .

Cell survival under stress is enhanced by a mitochondrial ATP-binding cassette transporter that regulates hemoproteins.

J. Schuetz, John Lynch, Y. Fukuda, 2009, Cancer research.

Role of NF-E2 related factor 2 (Nrf2) on chemotherapy resistance in acute myeloid leukemia (AML) and the effect of pharmacological inhibition of Nrf2

P. Balasubramanian, V. Mathews, P. Krishnamurthy, 2015, PloS one.

Hemoproteins ATP-Binding Cassette Transporter That Regulates Cell Survival under Stress Is Enhanced by a Mitochondrial

J. Schuetz, John Lynch, Y. Fukuda, 2009 .

The role of transporters in cellular heme and porphyrin homeostasis.

J. Schuetz, P. Krishnamurthy, Tao Xie, 2007, Pharmacology & therapeutics.

Role of ABCG2/BCRP in biology and medicine.

J. Schuetz, P. Krishnamurthy, J D Schuetz, 2006, Annual review of pharmacology and toxicology.

Sortilin 1 Modulates Hepatic Cholesterol Lipotoxicity in Mice via Functional Interaction with Liver Carboxylesterase 1*

Tiangang Li, P. Krishnamurthy, Feng Li, 2016, The Journal of Biological Chemistry.

Transporter-mediated protection against thiopurine-induced hematopoietic toxicity.

M. Relling, W. Evans, H. Nakauchi, 2008, Cancer research.

Sustained O-GlcNAcylation reprograms mitochondrial function to regulate energy metabolism

R. Swerdlow, U. Apte, D. Koestler, 2017, The Journal of Biological Chemistry.

Alternol eliminates excessive ATP production by disturbing Krebs cycle in prostate cancer

A. Artigues, J. Holzbeierlein, Benyi Li, 2019, The Prostate.

Biosynthetic Pathways Related to Cell Structure and Function

B. Dunn, P. Krishnamurthy, S. Phadnis, 2001 .

Metabolism of a Selective Serotonin and Norepinephrine Reuptake Inhibitor Duloxetine in Liver Microsomes and Mice

Lei Guo, Jin Wang, M. Matzuk, 2021, Drug Metabolism and Disposition.

Regulation of energy metabolism during early mammalian development: TEAD4 controls mitochondrial transcription

R. Swerdlow, Ram P Kumar, P. Krishnamurthy, 2018, Development.

Metabolomics reveals the formation of aldehydes and iminium in gefitinib metabolism.

Jin Wang, P. Krishnamurthy, Feng Li, 2015, Biochemical pharmacology.

Preliminary observations of mitochondrial dysfunction in Prader–Willi syndrome

M. Butler, P. Krishnamurthy, W. Hossain, 2018, American journal of medical genetics. Part A.

Functional Coupling of ATP-binding Cassette Transporter Abcb6 to Cytochrome P450 Expression and Activity in Liver*

K. Dorko, S. Kumer, P. Krishnamurthy, 2015, The Journal of Biological Chemistry.

Cancer-Associated Fibroblasts Drive Glycolysis in a Targetable Signaling Loop Implicated in Head and Neck Squamous Cell Carcinoma Progression.

B. Van Houten, O. Tawfik, S. Anant, 2018, Cancer research.