Owen J. Sansom

发表

LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency.

H. Augustin, C. Camilli, A. Dritsoula, 2021, Med.

mTORC1-selective activation of translation elongation promotes disease progression in chronic lymphocytic leukemia

A. Michie, N. Malik, Jodie Hay, 2023, Leukemia.

Co-inhibition of TGF-β and PD-L1 pathways in a metastatic colorectal cancer mouse model triggers interferon responses, innate cells and T cells, alongside metabolic changes and tumor resistance

S. Milling, Anna T. Andrusaite, T. Lannagan, 2024, Oncoimmunology.

A Review of Scheduling Strategies for Radiotherapy and Immune Checkpoint Inhibition in Locally Advanced Rectal Cancer

C. Steele, S. O'Cathail, Lydia Melissourgou-Syka, 2023, Journal of immunotherapy and precision oncology.

Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer

P. Dunne, C. Isella, L. Trusolino, 2024, Nature genetics.

Phosphorylation of Rab-coupling protein by LMTK3 controls Rab14-dependent EphA2 trafficking to promote cell:cell repulsion

J. Norman, O. Sansom, A. Campbell, 2017, Nature Communications.

JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors

J. Quinn, A. Roseweir, C. Steele, 2024, Journal of experimental & clinical cancer research : CR.

Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer

I. Tomlinson, K. Sheahan, J. Graham, 2020, The journal of pathology. Clinical research.

Ras mutation cooperates with β-catenin activation to drive bladder tumourigenesis

O. Sansom, M. Taketo, I. Ahmad, 2011, Cell Death and Disease.

A caveolin-dependent and PI3K/AKT-independent role of PTEN in β-catenin transcriptional activity

Z. Aktary, O. Sansom, F. Rambow, 2015, Nature Communications.