S. M. Roe

In vitro biological characterization of a novel, synthetic diaryl pyrazole resorcinol class of heat shock protein 90 inhibitors.

L. Pearl, P. Workman, R. Marais, 2007, Cancer research.

Structure of the TPR Domain of AIP: Lack of Client Protein Interaction with the C-Terminal α-7 Helix of the TPR Domain of AIP Is Sufficient for Pituitary Adenoma Predisposition

M. Korbonits, S. Roe, R. Morgan, 2012, PloS one.

Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex.

P. Cohen, L. Pearl, M. Peggie, 2005, Molecular cell.

Synthesis of 19-substituted geldanamycins with altered conformations and their binding to heat shock protein Hsp90.

David Siegel, William Lewis, Chrisostomos Prodromou, 2013, Nature chemistry.

Structure of an archaeal PCNA1–PCNA2–FEN1 complex: elucidating PCNA subunit and client enzyme specificity

L. Pearl, S. Bell, A. Oliver, 2006, Nucleic acids research.

Structural and functional analysis of the middle segment of hsp90: implications for ATP hydrolysis and client protein and cochaperone interactions.

Chrisostomos Prodromou, Bin Hu, Philippe Meyer, 2003, Molecular cell.

Tah1 helix-swap dimerization prevents mixed Hsp90 co-chaperone complexes

L. Pearl, S. Roe, R. Morgan, 2014, Acta crystallographica. Section D, Biological crystallography.

Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1

L. Pearl, S. Roe, C. Prodromou, 2014, Structure.

Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein

L. Pearl, F. Pearl, S. Ward, 2020, bioRxiv.