Dimitri Lavillette

发表

A Lentiviral Vector Allowing Physiologically Regulated Membrane-anchored and Secreted Antibody Expression Depending on B-cell Maturation Status.

S. Calattini, F. Cosset, M. Law, 2015, Molecular therapy : the journal of the American Society of Gene Therapy.

Structural Characterization of a Neutralizing Nanobody With Broad Activity Against SARS-CoV-2 Variants

D. Lavillette, Jingquan Tan, Dianfan Li, 2022, Frontiers in Microbiology.

Isolation, characterization, and structure-based engineering of a neutralizing nanobody against SARS-CoV-2

D. Lavillette, Jingquan Tan, Dianfan Li, 2022, International Journal of Biological Macromolecules.

A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection

Y. Bi, D. Lavillette, T. Kuiken, 2021, Nature Communications.

Discovery of nanobodies against SARS-CoV-2 and an uncommon neutralizing mechanism

D. Lavillette, Jingquan Tan, Dianfan Li, 2021, bioRxiv.

A potent synthetic nanobody targets RBD and protects mice from SARS-CoV-2 infection

Y. Bi, G. Wong, D. Lavillette, 2020, bioRxiv.

Cell surface receptors for gammaretroviruses.

D. Lavillette, M. Marin, C. Tailor, 2003, Current topics in microbiology and immunology.

A new class of broadly neutralizing antibodies that target the glycan loop of Zika virus envelope protein

Chao Zhang, Qingwei Liu, Zhong Huang, 2020, Cell Discovery.

EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy

F. Cosset, T. Pietschmann, O. Poch, 2011, Nature Medicine.

A high-affinity RBD-targeting nanobody improves fusion partner’s potency against SARS-CoV-2

D. Lavillette, Dianfan Li, Tingting Li, 2020, bioRxiv.

Receptor Complementation and Mutagenesis Reveal SR-BI as an Essential HCV Entry Factor and Functionally Imply Its Intra- and Extra-Cellular Domains

F. Zoulim, D. Lavillette, B. Bartosch, 2009, PLoS pathogens.

The Tight Junction-Associated Protein Occludin Is Required for a Postbinding Step in Hepatitis C Virus Entry and Infection

B. Bartosch, F. Cosset, R. Aldabe, 2009, Journal of Virology.

The Tight Junction Proteins Claudin-1, -6, and -9 Are Entry Cofactors for Hepatitis C Virus

D. Lavillette, F. Cosset, T. Dragic, 2008, Journal of Virology.

Matrigel-embedded 3D culture of Huh-7 cells as a hepatocyte-like polarized system to study hepatitis C virus cycle.

D. Lavillette, F. Cosset, T. Baumert, 2012, Virology.

Significant Redox Insensitivity of the Functions of the SARS-CoV Spike Glycoprotein

D. Lavillette, F. Cosset, I. Jones, 2006, Journal of Biological Chemistry.

The SARS-CoV-2 envelope and membrane proteins modulate maturation and retention of the spike protein, allowing assembly of virus-like particles

D. Lavillette, F. Cosset, B. Boson, 2020, Journal of Biological Chemistry.

Immunization with the receptor-binding domain of SARS-CoV-2 elicits antibodies cross-neutralizing SARS-CoV-2 and SARS-CoV without antibody-dependent enhancement

D. Qu, D. Lavillette, Chao Zhang, 2020, Cell Discovery.

Negligible contribution of M2634V substitution to ZIKV pathogenesis in AG6 mice revealed by a bacterial promoter activity reduced infectious clone

D. Lavillette, G. Long, Jin Zhong, 2018, Scientific Reports.

An Envelope Glycoprotein of the Human Endogenous Retrovirus HERV-W Is Expressed in the Human Placenta and Fuses Cells Expressing the Type D Mammalian Retrovirus Receptor

Bernard Mandrand, D. Lavillette, F. Cosset, 2000, Journal of Virology.

Up-Regulation of the ATP-Binding Cassette Transporter A1 Inhibits Hepatitis C Virus Infection

P. Roingeard, D. Lavillette, S. Pol, 2014, PloS one.

Human Serum Facilitates Hepatitis C Virus Infection, and Neutralizing Responses Inversely Correlate with Viral Replication Kinetics at the Acute Phase of Hepatitis C Virus Infection

J. Pawlotsky, D. Lavillette, P. Donot, 2005, Journal of Virology.

A Comparative Portrait of Retroviral Fusogens and Syncytins

D. Lavillette, F. Mallet, P. Pérot, 2011 .

Fusogenic membrane glycoproteins induce syncytia formation and death in vitro and in vivo: a potential therapy agent for lung cancer

E. Brambilla, D. Lavillette, F. Cosset, 2010, Cancer Gene Therapy.

Sustained E2 antibody response correlates with reduced peak viremia after hepatitis C virus infection in the chimpanzee

D. Lavillette, F. Cosset, Se-Hwan Yang, 2005, Hepatology.

The Envelope Glycoprotein of Human Endogenous Retrovirus Type W Uses a Divergent Family of Amino Acid Transporters/Cell Surface Receptors

D. Lavillette, F. Cosset, M. Marin, 2002, Journal of Virology.

SARS-CoV-2 spike engagement of ACE2 primes S2′ site cleavage and fusion initiation

D. Lavillette, Guangxun Meng, Bingjie Zhou, 2021, Proceedings of the National Academy of Sciences.

Cell Entry of Enveloped Viruses

D. Lavillette, F. Cosset, Dimitri Lavillette, 2011, Advances in Genetics.

Characterization of hepatitis C virus pseudoparticles by cryo-transmission electron microscopy using functionalized magnetic nanobeads.

F. Penin, D. Lavillette, B. Bartosch, 2010, The Journal of general virology.

Monoclonal Antibody AP33 Defines a Broadly Neutralizing Epitope on the Hepatitis C Virus E2 Envelope Glycoprotein

D. Lavillette, A. Tarr, B. Bartosch, 2005, Journal of Virology.

Virus-like particle vaccine induces cross-protection against human metapneumovirus infections in mice.

D. Lavillette, F. Cosset, J. Szécsi, 2013, Vaccine.

The antimalarial ferroquine is an inhibitor of hepatitis C virus†, ‡

C. Biot, D. Lavillette, J. Dubuisson, 2013, Hepatology.

Mechanism of Inhibition of Enveloped Virus Membrane Fusion by the Antiviral Drug Arbidol

B. Meier, F. Penin, D. Lavillette, 2011, PloS one.

Biochemical mechanism of hepatitis C virus inhibition by the broad-spectrum antiviral arbidol.

D. Lavillette, F. Cosset, S. Polyak, 2007, Biochemistry.

The SARS-CoV-2 Envelope and Membrane proteins modulate maturation and retention of the Spike protein, allowing optimal formation of VLPs in presence of Nucleoprotein

D. Lavillette, F. Cosset, B. Boson, 2020, bioRxiv.

The Exchangeable Apolipoprotein ApoC-I Promotes Membrane Fusion of Hepatitis C Virus*

S. Ricard-Blum, D. Lavillette, B. Bartosch, 2007, Journal of Biological Chemistry.

High Density Lipoprotein Inhibits Hepatitis C Virus-neutralizing Antibodies by Stimulating Cell Entry via Activation of the Scavenger Receptor BI*

Ralf Bartenschlager, Sylvie Ricard-Blum, Jean Dubuisson, 2006, Journal of Biological Chemistry.

An Interplay between Hypervariable Region 1 of the Hepatitis C Virus E2 Glycoprotein, the Scavenger Receptor BI, and High-Density Lipoprotein Promotes both Enhancement of Infection and Protection against Neutralizing Antibodies

F. Penin, J. Pawlotsky, D. Lavillette, 2005, Journal of Virology.

Kinases required in hepatitis C virus entry and replication highlighted by small interference RNA screening

D. Lavillette, P. Gripon, J. Le Seyec, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Characterization of host‐range and cell entry properties of the major genotypes and subtypes of hepatitis C virus

D. Lavillette, A. Tarr, C. Voisset, 2005, Hepatology.

Role of Hepatitis C Virus Envelope Glycoprotein E1 in Virus Entry and Assembly

D. Lavillette, Jin Zhong, Qingchao Li, 2018, Front. Immunol..

Co-Infection of Mosquitoes with Chikungunya and Dengue Viruses Reveals Modulation of the Replication of Both Viruses in Midguts and Salivary Glands of Aedes aegypti Mosquitoes

D. Missé, D. Lavillette, Alain Le Coupanec, 2017, International journal of molecular sciences.

Antibody-mediated spike activation promotes cell-cell transmission of SARS-CoV-2

Bingjie Zhou, Ting-Yi Li, Yapei Zhao, 2023, PLoS pathogens.

Uncovering a conserved vulnerability site in SARS‐CoV‐2 by a human antibody

Y. Bi, D. Lavillette, T. Kuiken, 2021, EMBO molecular medicine.

A Prime-Boost Strategy Using Virus-Like Particles Pseudotyped for HCV Proteins Triggers Broadly Neutralizing Antibodies in Macaques

P. Mangeot, D. Lavillette, F. Cosset, 2011, Science Translational Medicine.

Low cross-neutralization of hepatitis C correlates with liver disease in immunocompromized patients

D. Lavillette, F. Cosset, D. Samuel, 2015, AIDS.

N-Linked Glycosylation and Sequence Changes in a Critical Negative Control Region of the ASCT1 and ASCT2 Neutral Amino Acid Transporters Determine Their Retroviral Receptor Functions

D. Lavillette, M. Marin, D. Kabat, 2003, Journal of Virology.

The mechanism of HCV entry into host cells.

D. Lavillette, F. Cosset, Florian Douam, 2015, Progress in molecular biology and translational science.

Mapping cross-variant neutralizing sites on the SARS-CoV-2 spike protein

D. Lavillette, Chao Zhang, Yong Yang, 2021, Emerging microbes & infections.

Zika virus pathogenesis and current therapeutic advances

D. Lavillette, Zhiming Yuan, Raphael Nyaruaba, 2020, Pathogens and global health.

Characterization of Fusion Determinants Points to the Involvement of Three Discrete Regions of Both E1 and E2 Glycoproteins in the Membrane Fusion Process of Hepatitis C Virus

F. Penin, D. Lavillette, P. Donot, 2007, Journal of Virology.

Baboon envelope pseudotyped LVs outperform VSV-G-LVs for gene transfer into early-cytokine-stimulated and resting HSCs.

F. Cosset, D. Nègre, E. Verhoeyen, 2014, Blood.

Yeast-produced subunit protein vaccine elicits broadly neutralizing antibodies that protect mice against Zika virus lethal infection.

D. Lavillette, Wei Zhang, Chao Zhang, 2019, Antiviral research.

Floriane transfer into early-cytokine-stimulated and resting HSCs Baboon envelope pseudotyped LVs outperform VSV-G-LVs for gene

D. Lavillette, F. Cosset, D. Nègre, 2014 .

The Sheep Tetherin Paralog oBST2B Blocks Envelope Glycoprotein Incorporation into Nascent Retroviral Virions

D. Lavillette, T. Spencer, M. Palmarini, 2014, Journal of Virology.

A protein coevolution method uncovers critical features of the Hepatitis C Virus fusion mechanism

A. Carbone, D. Lavillette, F. Cosset, 2018, PLoS pathogens.

A Proline-Rich Motif Downstream of the Receptor Binding Domain Modulates Conformation and Fusogenicity of Murine Retroviral Envelopes

M. Sitbon, D. Lavillette, F. Cosset, 1998, Journal of Virology.

Extracellular vesicles from Zika virus‐infected cells display viral E protein that binds ZIKV‐neutralizing antibodies to prevent infection enhancement

R. Bartenschlager, D. Lavillette, G. Long, 2023, The EMBO journal.

Retargeting gene delivery using surface-engineered retroviral vector particles.

D. Lavillette, F. Cosset, S. Russell, 2001, Current opinion in biotechnology.

Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections

D. Qu, D. Lavillette, Chao Zhang, 2021, Nature communications.

Comparative study of chikungunya Virus-Like Particles and Pseudotyped-Particles used for serological detection of specific immunoglobulin M.

B. Coutard, D. Lavillette, P. Dalbon, 2019, Virology.

Fusogenic membrane glycoproteins as a novel class of genes for the local and immune-mediated control of tumor growth.

R. Vile, D. Lavillette, F. Cosset, 2000, Cancer research.