Nalini Sadagopan

发表

Discovery of PF-04457845: A Highly Potent, Orally Bioavailable, and Selective Urea FAAH Inhibitor.

Shobha N. Bhattachar, B. Cravatt, D. T. Dudley, 2011, ACS medicinal chemistry letters.

Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain.

R. Stevens, J. Long, B. Cravatt, 2009, Chemistry & biology.

Investigation of EDTA anticoagulant in plasma to improve the throughput of liquid chromatography/tandem mass spectrometric assays.

L. Cohen, David L Weller, J. Cook, 2003, Rapid communications in mass spectrometry : RCM.

Induction of Drug Metabolism Enzymes and MDR1 Using a Novel Human Hepatocyte Cell Line

J. Sahi, S. D. de Morais, N. Sadagopan, 2004, Journal of Pharmacology and Experimental Therapeutics.

Circulating succinate is elevated in rodent models of hypertension and metabolic disease.

T. Major, S. Roberds, Ying Yu, 2007, American journal of hypertension.

Mechanistic and Pharmacological Characterization of PF-04457845: A Highly Potent and Selective Fatty Acid Amide Hydrolase Inhibitor That Reduces Inflammatory and Noninflammatory Pain

Benjamin F. Cravatt, Paul Wren, Shobha N. Bhattachar, 2011, Journal of Pharmacology and Experimental Therapeutics.

Mechanistic and pharmacological characterization of PF-04457845 : a highly potent and selective FAAH inhibitor that reduces inflammatory and noninflammatory pain

Shobha N. Bhattachar, D. Nomura, B. Cravatt, 2011 .

A universal strategy for development of a method for absolute quantification of therapeutic monoclonal antibodies in biological matrices using differential dimethyl labeling coupled with ultra performance liquid chromatography-tandem mass spectrometry.

N. Sadagopan, Chengjie Ji, C. Lepsy, 2009, Analytical chemistry.

An efficient approach for the rapid assessment of oral rat exposures for new chemical entities in drug discovery.

Kjell Johnson, Hyo-Kyung Han, Kjell Johnson, 2006, Journal of pharmaceutical sciences.

Development and validation of an LC-MS/MS method for quantification of cyclic guanosine 3',5'-monophosphate (cGMP) in clinical applications: a comparison with a EIA method.

D. Dufield, N. Sadagopan, Yanhua Zhang, 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Charge derivatization of peptides for analysis by mass spectrometry.

J. Watson, N. Sadagopan, Z. H. Huang, 1998, Mass spectrometry reviews.

EFFECTS OF AVASIMIBE ON CYTOCHROME P450 2C9 EXPRESSION IN VITRO AND IN VIVO

J. Sahi, M. Milad, Xianxian Zheng, 2004, Drug Metabolism and Disposition.

Evaluation of online extraction/mass spectrometry for in vivo cassette analysis.

L. Cohen, N. Sadagopan, Brandon A Pabst, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Development of a multiplex UPLC-MRM MS method for quantification of human membrane transport proteins OATP1B1, OATP1B3 and OATP2B1 in in vitro systems and tissues.

N. Sadagopan, M. Ullah, W. Tschantz, 2012, Analytica chimica acta.

Discovery of potent selective bioavailable phosphodiesterase 2 (PDE2) inhibitors active in an osteoarthritis pain model. Part II: optimization studies and demonstration of in vivo efficacy.

J. Pandit, C. Whitehead, Cindy Spessard, 2013, Bioorganic & medicinal chemistry letters.

Investigation of the tris(trimethoxyphenyl)phosphonium acetyl charged derivatives of peptides by electrospray ionization mass spectrometry and tandem mass spectrometry

J. Watson, N. Sadagopan, Nalini Sadagopan, 2000, Journal of the American Society for Mass Spectrometry.