Christian P. Larsen

Heterologous immunity provides a potent barrier to transplantation tolerance.

E. Wherry, K. Kokko, R. Ahmed, 2003, The Journal of clinical investigation.

CD40-CD40 ligand costimulation is required for generating antiviral CD4 T cell responses but is dispensable for CD8 T cell responses.

R. Ahmed, R. Flavell, C. Larsen, 1999, Journal of immunology.

Transplantation tolerance induced by CTLA4-Ig.

P. Linsley, C. Larsen, D. Alexander, 1994, Transplantation.

CD122 signaling in CD8+ memory T cells drives costimulation-independent rejection

C. Larsen, J. Tso, A. Adams, 2018, The Journal of clinical investigation.

An Anti‐CD154 Domain Antibody Prolongs Graft Survival and Induces Foxp3+ iTreg in the Absence and Presence of CTLA‐4 Ig

A. Yamniuk, S. Grant, S. Nadler, 2013, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Conventional immunosuppression and co-stimulation blockade.

C. Larsen, T. Pearson, A. Adams, 2001, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

4-1BB ligand, a member of the TNF family, is important for the generation of antiviral CD8 T cell responses.

R. Ahmed, C. Larsen, T. Pearson, 1999, Journal of immunology.

High CTLA‐4 Expression on Th17 Cells Results in Increased Sensitivity to CTLA‐4 Coinhibition and Resistance to Belatacept

A. Mehta, A. Kirk, C. Larsen, 2014, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Transplantation of the bone marrow microenvironment leads to hematopoietic chimerism without cytoreductive conditioning.

C. Larsen, D. Alexander, C. Tucker-Burden, 2000, Transplantation.

CTLA4-Ig plus bone marrow induces long-term allograft survival and donor specific unresponsiveness in the murine model. Evidence for hematopoietic chimerism.

P. Linsley, C. Larsen, E. Elwood, 1996, Transplantation.

A New Look at Blockade of T‐cell Costimulation: A Therapeutic Strategy for Long‐term Maintenance Immunosuppression

A. Kirk, S. Knechtle, C. Larsen, 2006, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Miles to Go…

K. Newell, Christian P. Larsen, T. Pearson, 2011, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Analysis of expression and function of the costimulatory molecule 4-1BB in alloimmune responses.

C. Larsen, R. Hendrix, C. Tucker-Burden, 2000, Transplantation.

Analysis of the B7 costimulatory pathway in allograft rejection.

P. Linsley, C. Larsen, D. Alexander, 1997, Transplantation.