Susumu Kohno

发表

Peripubertal high‐fat diet promotes c‐Myc stabilization in mammary gland epithelium

Sharad Kumar, S. Kohno, C. Takahashi, 2020, Cancer science.

Establishment and characterization of a noradrenergic adrenal chromaffin cell line, tsAM5NE, immortalized with the temperature‐sensitive SV40 T‐antigen

Naoshi Koide, T. Murata, K. Hikita, 2011, Cell biology international.

Inhibition of the mitochondria-shaping protein Opa1 restores sensitivity to Gefitinib in a lung adenocarcinomaresistant cell line

L. Scorrano, T. Kohno, A. Hirao, 2023, Cell Death & Disease.

Methyl galbanate, a novel inhibitor of nitric oxide production in mouse macrophage RAW264.7 cells

T. Murata, K. Hikita, N. Kaneda, 2011, Journal of Natural Medicines.

ATM Mediates pRB Function To Control DNMT1 Protein Stability and DNA Methylation

Y. Doki, Ken‐ichi Yamamoto, Misa Suzuki, 2013, Molecular and Cellular Biology.

ATM mediates pRBfunction to control DNMT1 protein stability and DNA methylation

Y. Doki, Ken‐ichi Yamamoto, Misa Suzuki, 2013 .

Metabolic characterization of cultured mammalian cells by mass balance analysis, tracer labeling experiments and computer-aided simulations.

H. Shimizu, N. Okahashi, S. Kitajima, 2015, Journal of bioscience and bioengineering.

NFYA promotes malignant behavior of triple-negative breast cancer in mice through the regulation of lipid metabolism

N. Okada, C. Takahashi, K. Yoshikawa, 2023, Communications biology.

Metabolic flux and flux balance analyses indicate the relevance of metabolic thermogenesis and aerobic glycolysis in cancer cells

H. Shimizu, Chie Araki, N. Okahashi, 2023, bioRxiv.

Aerobic glycolysis in cancer cells supplies ATP while preventing excess metabolic thermogenesis

H. Shimizu, Chie Araki, H. Uehara, 2021 .

Retinoblastoma tumor suppressor functions shared by stem cell and cancer cell strategies.

S. Kitajima, S. Kohno, C. Takahashi, 2016, World journal of stem cells.

Glucoraphanin Ameliorates Obesity and Insulin Resistance Through Adipose Tissue Browning and Reduction of Metabolic Endotoxemia in Mice

Shuichi Kaneko, Chiaki Takahashi, Hiroyuki Suganuma, 2017, Diabetes.

The RB–IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity

M. Ewen, D. Barbie, T. Nishiuchi, 2017, Oncogene.

Basic fibroblast growth factor promotes glial cell-derived neurotrophic factor gene expression mediated by activation of ERK5 in rat C6 glioma cells.

W. Nemoto, Y. Obara, N. Nakahata, 2011, Cellular signalling.

Pharmacologically targetable vulnerability in prostate cancer carrying RB1-SUCLA2 deletion

T. Soga, Sharad Kumar, S. Kohno, 2020, Oncogene.

Retinoblastoma inactivation induces a protumoral microenvironment via enhanced CCL2 secretion.

D. Barbie, Tomoaki Tanaka, N. Okada, 2019, Cancer research.

RHEB is a potential therapeutic target in T cell acute lymphoblastic leukemia.

P. Worley, M. Ueno, A. Hirao, 2022, Biochemical and biophysical research communications.

Inhibitory effect of carbazolequinone derivatives on lipopolysaccharide and interferon‐γ‐induced nitric oxide production in mouse macrophage RAW264.7 cells

M. Itoigawa, T. Murata, K. Hikita, 2013, The Journal of pharmacy and pharmacology.

Autocrine TGF-β signaling is required for the GDNF/CNTF-induced neuronal differentiation of adrenal chromaffin tsAM5D cells expressing temperature-sensitive SV40 T-antigen

Naoshi Koide, T. Murata, M. Tsuboi, 2008, Neuroscience Letters.

Neuronal differentiation elicited by glial cell line‐derived neurotrophic factor and ciliary neurotrophic factor in adrenal chromaffin cell line tsAM5D immortalized with temperature‐sensitive SV40 T‐antigen

Naoshi Koide, T. Murata, K. Hikita, 2008, Journal of neuroscience research.

A distinct function of the retinoblastoma protein in the control of lipid composition identified by lipidomic profiling

N. Okada, H. Shimano, T. Matsuzaka, 2017, Oncogenesis.

Undifferentiated State Induced by Rb‐p53 Double Inactivation in Mouse Thyroid Neuroendocrine Cells and Embryonic Fibroblasts

Misa Suzuki, S. Kitajima, S. Kohno, 2015, Stem cells.

MicroRNA-140 mediates RB tumor suppressor function to control stem cell-like activity through interleukin-6

D. Barbie, Tomoaki Tanaka, T. Nishiuchi, 2017, Oncotarget.

Targeting RB1 Loss in Cancers

D. Voon, S. Kohno, C. Takahashi, 2021, Cancers.

Therapeutic Strategy for Targeting Aggressive Malignant Gliomas by Disrupting Their Energy Balance*

T. Todo, T. Soga, M. Ueno, 2016, The Journal of Biological Chemistry.

Essential role of autophagy in protecting neonatal haematopoietic stem cells from oxidative stress in a p62-independent manner

M. Komatsu, M. Ueno, A. Hirao, 2021, Scientific Reports.

Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2

T. Soga, N. Mukaida, Kaori Saitoh, 2018, Oncogene.

An in vitro system to characterize prostate cancer progression identified signaling required for self‐renewal

T. Nishiuchi, S. Kitajima, S. Kohno, 2016, Molecular carcinogenesis.

RB1 loss induces quiescent state through downregulation of RAS signaling in mammary epithelial cells

Susumu Kohno, D. C. Voon, Chiaki Takahashi, 2024, Cancer science.

Regucalcin enhances adipocyte differentiation and attenuates inflammation in 3T3‐L1 cells

T. Murata, K. Hikita, N. Kaneda, 2020, FEBS open bio.

Treatment of Retinoblastoma 1–Intact Hepatocellular Carcinoma With Cyclin‐Dependent Kinase 4/6 Inhibitor Combination Therapy

H. Shimizu, F. Matsuda, N. Okada, 2021, Hepatology.