Laura González-Lafuente

发表

Partial Genetic Deletion of Klotho Aggravates Cardiac Calcium Mishandling in Acute Kidney Injury

L. Ruilope, M. Kuro-o, E. Rodríguez-Sánchez, 2023, International journal of molecular sciences.

The anti-aging factor Klotho protects against acquired long QT syndrome induced by uremia and promoted by fibroblast growth factor 23

L. Ruilope, M. Kuro-o, C. Delgado, 2022, BMC Medicine.

Interplay between mineral bone disorder and cardiac damage in acute kidney injury: from Ca2+ mishandling and preventive role of Klotho in mice to its potential mortality prediction in human.

L. Ruilope, M. Kuro-o, F. Liaño, 2022, Translational research : the journal of laboratory and clinical medicine.

Fibroblast Growth Factor-23-Klotho Axis in Cardiorenal Syndrome: Mediators and Potential Therapeutic Targets

L. Ruilope, G. Ruiz‐Hurtado, M. Fernández-Velasco, 2021, Frontiers in Physiology.

An Overview of FGF-23 as a Novel Candidate Biomarker of Cardiovascular Risk

L. Ruilope, E. Rodríguez-Sánchez, G. Ruiz‐Hurtado, 2021, Frontiers in Physiology.

Enhanced Klotho availability protects against cardiac dysfunction induced by uraemic cardiomyopathy by regulating Ca2+ handling

L. Ruilope, M. Kuro-o, E. Rodríguez-Sánchez, 2020, British journal of pharmacology.

Gramine Derivatives Targeting Ca(2+) Channels and Ser/Thr Phosphatases: A New Dual Strategy for the Treatment of Neurodegenerative Diseases.

L. Gandía, J. Arranz-Tagarro, L. González-Lafuente, 2016, Journal of medicinal chemistry.

Benzothiazepine CGP37157 and its isosteric 2'-methyl analogue provide neuroprotection and block cell calcium entry.

C. Pérez, R. León, Manuela G. López, 2012, ACS chemical neuroscience.

Unilateral Acute Renal Ischemia-Reperfusion Injury Induces Cardiac Dysfunction through Intracellular Calcium Mishandling

E. Rodríguez-Sánchez, G. Ruiz‐Hurtado, M. Carneiro-Ramos, 2022, International journal of molecular sciences.

ConBr, A Lectin Purified from the Seeds of Canavalia brasiliensis, Protects Against Ischemia in Organotypic Culture of Rat Hippocampus: Potential Implication of Voltage-Gated Calcium Channels

R. León, D. Rieger, K. Nascimento, 2016, Neurochemical Research.

Mitogen-Activated Protein Kinase 14 Promotes AKI.

H. Husi, M. Sánchez-Niño, H. Mischak, 2017, Journal of the American Society of Nephrology : JASN.

K 14 promotes acute kidney injury

H. Husi, M. Sánchez-Niño, H. Mischak, 2016 .

An improved understanding of pathogenic pathways may identify novel acute kidney injury

H. Husi, M. Sánchez-Niño, H. Mischak, 2016 .

Synthesis, structure, theoretical and experimental in vitro antioxidant/pharmacological properties of α-aryl, N-alkyl nitrones, as potential agents for the treatment of cerebral ischemia.

B. Bartolomé, Abdelouahid Samadi, E. Soriano, 2011, Bioorganic & medicinal chemistry.

Lifetime cardiovascular risk is associated with a multimarker score of systemic oxidative status in young adults independently of traditional risk factors.

L. Ruilope, G. Álvarez-Llamas, E. Rodríguez-Sánchez, 2019, Translational research : the journal of laboratory and clinical medicine.

Benzothiazepine CGP37157 Analogues Exert Cytoprotection in Various in Vitro Models of Neurodegeneration.

L. González-Lafuente, C. de los Ríos, M. Cano-Abad, 2015, ACS chemical neuroscience.

PP2A ligand ITH12246 protects against memory impairment and focal cerebral ischemia in mice.

Manuela G. López, Abdelouahid Samadi, J. Marco-Contelles, 2013, ACS chemical neuroscience.

Non-canonical NFκB activation promotes chemokine expression in podocytes

M. Sánchez-Niño, A. Sanz, A. Ortiz, 2016, Scientific Reports.

Klotho relieves inflammation and exerts a cardioprotective effect during renal ischemia/reperfusion-induced cardiorenal syndrome.

E. Rodríguez-Sánchez, G. Ruiz‐Hurtado, M. Carneiro-Ramos, 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Genetic Deletion of NOD1 Prevents Cardiac Ca2+ Mishandling Induced by Experimental Chronic Kidney Disease

L. Ruilope, C. Delgado, G. Ruiz‐Hurtado, 2020, International journal of molecular sciences.

Analysis of global oxidative status using multimarker scores reveals a specific association between renal dysfunction and diuretic therapy in older adults.

L. Ruilope, G. Álvarez-Llamas, M. Baldan-Martin, 2021, The journals of gerontology. Series A, Biological sciences and medical sciences.

Neuroprotective mechanism of the novel melatonin derivative Neu-P11 in brain ischemia related models

R. León, Manuela G. López, M. Laudon, 2015, Neuropharmacology.

Synthesis, pharmacological assessment, and molecular modeling of acetylcholinesterase/butyrylcholinesterase inhibitors: effect against amyloid-β-induced neurotoxicity.

P. Agostinho, C. Pérez, Ignacio Moraleda, 2013, ACS chemical neuroscience.