Joachim Degen

发表

The conditional connexin43G138R mouse mutant represents a new model of hereditary oculodentodigital dysplasia in humans.

J. Degen, K. Willecke, B. Fleischmann, 2008, Human molecular genetics.

Cardiomyocyte-restricted deletion of connexin43 during mouse development.

Michael D. Schneider, P. Doevendans, J. Degen, 2006, Journal of molecular and cellular cardiology.

Slow Conduction and Enhanced Anisotropy Increase the Propensity for Ventricular Tachyarrhythmias in Adult Mice With Induced Deletion of Connexin43

Tobias Opthof, Jacques M T de Bakker, Harold V M van Rijen, 2004, Circulation.

Functional role of connexin43 gap junction channels in adult mouse heart assessed by inducible gene deletion.

J. Degen, K. Willecke, J. D. de Bakker, 2004, Journal of molecular and cellular cardiology.

Connexin30.2 containing gap junction channels decelerate impulse propagation through the atrioventricular node.

Alexander Ghanem, Klaus Tiemann, Thorsten Lewalter, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Tagger—A Swiss army knife for multiomics to dissect cell type–specific mechanisms of gene expression in mice

V. Bansal, W. Jackson, J. Degen, 2019, PLoS biology.

Quality control of astrocyte‐directed Cre transgenic mice: The benefits of a direct link between loss of gene expression and reporter activation

J. Degen, K. Willecke, C. Steinhäuser, 2009, Glia.

Functional Expression of the Murine Connexin 36 Gene Coding for a Neuron-Specific Gap Junctional Protein

B. Teubner, J. Degen, K. Willecke, 2000, The Journal of Membrane Biology.

Expression pattern of lacZ reporter gene representing connexin36 in transgenic mice

J. Degen, K. Willecke, R. S. van der Giessen, 2004, The Journal of comparative neurology.

Replacement by a lacZ reporter gene assigns mouse connexin36, 45 and 43 to distinct cell types in pancreatic islets.

J. Degen, K. Willecke, A. Charollais, 2004, Experimental cell research.

A new conditional mouse mutant reveals specific expression and functions of connexin36 in neurons and pancreatic beta-cells.

J. Deuchars, K. Wellershaus, J. Degen, 2008, Experimental cell research.

Connexin36 mediates gap junctional coupling of alpha‐ganglion cells in mouse retina

Timm Schubert, Hannah Monyer, R. Weiler, 2005, The Journal of comparative neurology.

Structural and Functional Diversity of Connexin Genes in the Mouse and Human Genome

J. Degen, K. Willecke, Jürgen Eiberger, 2002, Biological chemistry.

Ceramide synthase 4 deficiency in mice causes lipid alterations in sebum and results in alopecia.

J. Degen, K. Willecke, P. Dörmann, 2014, The Biochemical journal.

Deletion of Connexin45 in Mouse Retinal Neurons Disrupts the Rod/Cone Signaling Pathway between AII Amacrine and ON Cone Bipolar Cells and Leads to Impaired Visual Transmission

R. Weiler, J. Ammermüller, J. Degen, 2005, The Journal of Neuroscience.

Behavioral alterations and changes in Ca/calmodulin kinase II levels in the striatum of connexin36 deficient mice

J. P. Huston, J. Degen, K. Willecke, 2012, Behavioural Brain Research.

Ceramide Synthase 5 Is Essential to Maintain C16:0-Ceramide Pools and Contributes to the Development of Diet-induced Obesity*

M. Hoch, J. Degen, P. Dörmann, 2016, The Journal of Biological Chemistry.

- 1-Ceramide Synthase 5 Is Essential to Maintain C 16 : 0 Ceramide Pools and Contributes to the Development of Diet Induced Obesity

M. Hoch, J. Degen, P. Dörmann, 2016 .

New insights into the expression and function of neural connexins with transgenic mouse mutants

J. Degen, K. Willecke, B. Odermatt, 2004, Brain Research Reviews.

Characterization of Panglial Gap Junction Networks in the Thalamus, Neocortex, and Hippocampus Reveals a Unique Population of Glial Cells.

D. Cope, V. Crunelli, J. Degen, 2015, Cerebral cortex.

Connexin 47 (Cx47)-Deficient Mice with Enhanced Green Fluorescent Protein Reporter Gene Reveal Predominant Oligodendrocytic Expression of Cx47 and Display Vacuolized Myelin in the CNS

K. Wellershaus, J. Degen, K. Willecke, 2003, The Journal of Neuroscience.

Efficient genome engineering by targeted homologous recombination in mouse embryos using transcription activator-like effector nucleases

J. Degen, M. Beyer, J. Schultze, 2014, Nature Communications.

Visual Transmission Deficits in Mice with Targeted Disruption of the Gap Junction Gene Connexin36

R. Weiler, A. Feigenspan, J. Ammermüller, 2001, The Journal of Neuroscience.

Characterization of connexin30.3-deficient mice suggests a possible role of connexin30.3 in olfaction.

J. Degen, K. Willecke, E. Dere, 2007, European journal of cell biology.

Functional Expression of the New Gap Junction Gene Connexin47 Transcribed in Mouse Brain and Spinal Cord Neurons

J. Degen, K. Willecke, K. Schilling, 2001, The Journal of Neuroscience.

The murine gap junction gene connexin36 is highly expressed in mouse retina and regulated during brain development

J. Degen, K. Willecke, G. Söhl, 1998, FEBS letters.

Role of Olivary Electrical Coupling in Cerebellar Motor Learning

J. Deuchars, H. Monyer, C. I. Zeeuw, 2008, Neuron.

Immunohistochemical detection of the neuronal connexin36 in the mouse central nervous system in comparison to connexin36-deficient tissues

K. Willecke, R. Dermietzel, C. Meier, 2002, Histochemistry and Cell Biology.

Adult Ceramide Synthase 2 (CERS2)-deficient Mice Exhibit Myelin Sheath Defects, Cerebellar Degeneration, and Hepatocarcinomas*

J. Degen, K. Willecke, D. Hartmann, 2009, The Journal of Biological Chemistry.

Inactivation of Ceramide Synthase 6 in Mice Results in an Altered Sphingolipid Metabolism and Behavioral Abnormalities*

J. Degen, K. Willecke, E. Dere, 2013, The Journal of Biological Chemistry.

Ablation of Neuronal Ceramide Synthase 1 in Mice Decreases Ganglioside Levels and Expression of Myelin-associated Glycoprotein in Oligodendrocytes*

J. Degen, K. Willecke, E. Dere, 2012, The Journal of Biological Chemistry.

Correction: Tagger—A Swiss army knife for multiomics to dissect cell type–specific mechanisms of gene expression in mice

A. Rajput, Martin Fuhrmann, Lech Kaczmarczyk, 2022, PLoS biology.

Pathologic and Phenotypic Alterations in a Mouse Expressing a Connexin47 Missense Mutation That Causes Pelizaeus-Merzbacher–Like Disease in Humans

J. Degen, K. Willecke, E. Dere, 2011, PLoS genetics.

Functional characterization of enzymes catalyzing ceramide phosphoethanolamine biosynthesis in mice[S]

J. Degen, K. Willecke, D. Vance, 2015, Journal of Lipid Research.

The oligodendroglial precursor cell line Oli-neu represents a cell culture system to examine functional expression of the mouse gap junction gene connexin29 (Cx29)

J. Degen, B. Odermatt, G. Söhl, 2013, Front. Pharmacol..

Connexin Genes in the Mouse and Human Genome

J. Degen, K. Willecke, Jürgen Eiberger, 2001, Cell communication & adhesion.

Peripheral lymphangiogenesis in mice depends on ectodermal connexin-26 (Gjb2)

J. Degen, K. Willecke, T. Bald, 2011, Journal of Cell Science.