Jérémie Vendôme

发表

In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas

J. Sacchettini, J. Vendôme, V. Feher, 2022, Journal of medicinal chemistry.

Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis

J. Sacchettini, T. Ioerger, J. Vendôme, 2018, ACS infectious diseases.

Linking molecular affinity and cellular specificity in cadherin-mediated adhesion

L Shapiro, B. Honig, T. Jessell, 2009, Proceedings of the National Academy of Sciences.

Structural and energetic determinants of adhesive binding specificity in type I cadherins

Julia Brasch, Fabiana Bahna, Barry Honig, 2014, Proceedings of the National Academy of Sciences.

Nectin ectodomain structures reveal a canonical adhesive interface

B. Honig, Soonjin Hong, L. Shapiro, 2012, Nature Structural &Molecular Biology.

Evidence for the early emergence of piperaquine-resistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance

M. Eppstein, P. Roepe, D. Fidock, 2022, PLoS pathogens.

Structure and Drug Resistance of the Plasmodium falciparum Transporter PfCRT

Yong Zi Tan, P. Roepe, D. Fidock, 2019, Nature.

Identification of a Novel 1,2,3,4-Tetrahydrobenzo[b][1,6]naphthyridine Analogue as a Potent Phosphodiesterase 5 Inhibitor with Improved Aqueous Solubility for the Treatment of Alzheimer's Disease.

O. Arancio, J. Vendôme, D. Landry, 2017, Journal of medicinal chemistry.

Loop L5 Acts as a Conformational Latch in the Mitotic Kinesin Eg5*

B. Honig, S. Rosenfeld, J. Vendôme, 2010, The Journal of Biological Chemistry.

The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain

Wael E Houssen, J. Naismith, J. Vendôme, 2012, Nature Structural &Molecular Biology.

T-cadherin structures reveal a novel adhesive binding mechanism

B. Honig, T. Jessell, L. Shapiro, 2010, Nature Structural &Molecular Biology.

Structures of aminoarabinose transferase ArnT suggest a molecular basis for lipid A glycosylation

B. Rost, E. Kloppmann, L. Shapiro, 2016, Science.

Splice Form Dependence of β-Neurexin/Neuroligin Binding Interactions

B. Honig, L. Shapiro, F. Bahna, 2010, Neuron.

Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance

M. Foley, P. Rosenthal, P. Bhanot, 2018, Proceedings of the National Academy of Sciences.

Development of a highly selective Plasmodium falciparum proteasome inhibitor with anti-malaria activity in humanized mice.

P. Rosenthal, J. Vendôme, M. Michino, 2021, Angewandte Chemie.

Silencing c-Myc translation as a therapeutic strategy through targeting PI3Kδ and CK1ε in hematological malignancies.

B. Honig, N. Tatonetti, J. Vendôme, 2017, Blood.

The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins.

B. Honig, J. Frank, Soonjin Hong, 2011, Structure.

Enhancing Hit Discovery in Virtual Screening through Absolute Protein-Ligand Binding Free-Energy Calculations.

R. Friesner, J. Vendôme, Robert Abel, 2023, Journal of chemical information and modeling.

Induced-Fit Docking Enables Accurate Free Energy Perturbation Calculations in Homology Models.

R. Friesner, K. Borrelli, Kai Zhu, 2022, Journal of chemical theory and computation.

Two-step adhesive binding by classical cadherins

B. Honig, L. Shapiro, O. Harrison, 2010, Nature Structural &Molecular Biology.

Silencing c-Myc Translation As a Therapeutic Strategy through Targeting PI3K Delta and CK1 Epsilon in Hematological Malignancies

B. Honig, N. Tatonetti, J. Vendôme, 2016 .

Design, Synthesis, and Optimization of Macrocyclic Peptides as Species-Selective Antimalaria Proteasome Inhibitors.

J. Vendôme, M. Michino, C. Nathan, 2022, Journal of medicinal chemistry.

Molecular design principles underlying β-strand swapping in the adhesive dimerization of cadherins

Fabiana Bahna, Barry Honig, Lawrence Shapiro, 2011, Nature Structural &Molecular Biology.

Molecular modeling of wild-type and D816V c-Kit inhibition based on ATP-competitive binding of ellipticine derivatives to tyrosine kinases.

Christian Auclair, P. Dubreuil, M. Le Bret, 2005, Journal of medicinal chemistry.

Transforming binding affinities from 3D to 2D with application to cadherin clustering

B. Honig, L. Shapiro, A. Ben-Shaul, 2011, Nature.