P. M. Conn

发表

Addition of catfish gonadotropin-releasing hormone (GnRH) receptor intracellular carboxyl-terminal tail to rat GnRH receptor alters receptor expression and regulation.

S. Brothers, J. Janovick, Jan Bogerd, 1998, Molecular endocrinology.

Addition of Catfish Gonadotropin- Releasing Hormone (gnrh) Receptor Intracellular Carboxyl- Terminal Tail to Rat Gnrh Receptor Alters Receptor Expression and Regulation Mammalian Gnrh Receptor (gnrhr) Is Unique among G Protein-coupled Seven-transmembrane Segment Receptors Due to the Absence of an In

S. Brothers, P. Conn, J. Janovick, 2022 .

Rescue of misrouted GnRHR mutants reveals its constitutive activity.

I. Pogozheva, A. Cornea, J. Janovick, 2012, Molecular endocrinology.

Quality control autophagy degrades soluble ERAD-resistant conformers of the misfolded membrane protein GnRHR.

D. Cyr, J. Janovick, Scott A. Houck, 2014, Molecular cell.

Regulation of RGS3 and RGS10 Palmitoylation by GnRH.

S. Brothers, R. Fisher, P. Conn, 2002, Endocrinology.

Caldesmon: a bifunctional (calmodulin and actin) binding protein which regulates stimulated gonadotropin release.

P. Conn, J. Janovick, F. Longo, 1991, Endocrinology.

Receptor-misrouting: an unexpectedly prevalent and rescuable etiology in gonadotropin-releasing hormone receptor-mediated hypogonadotropic hypogonadism.

P. Conn, J. Janovick, A. Leaños-Miranda, 2002, The Journal of clinical endocrinology and metabolism.

Chaperoning G protein-coupled receptors: from cell biology to therapeutics.

P. Conn, Y. Tao, P. Michael Conn, 2014, Endocrine reviews.

Combined administration of a gonadotropin-releasing hormone antagonist and testosterone in men induces reversible azoospermia without loss of libido.

J. Lindner, W. Vale, P. Conn, 1991, The Journal of clinical endocrinology and metabolism.

Pharmacological profile of a new, potent, and long-acting gonadotropin-releasing hormone antagonist: degarelix.

Jean E Rivier, J. Rivier, P. Conn, 2002, The Journal of pharmacology and experimental therapeutics.

Assay strategies for identification of therapeutic leads that target protein trafficking.

J. Janovick, L. Scampavia, Timothy P. Spicer, 2015, Trends in pharmacological sciences.

Rescue of hypogonadotropic hypogonadism-causing and manufactured GnRH receptor mutants by a specific protein-folding template: misrouted proteins as a novel disease etiology and therapeutic target.

P. Conn, J. Janovick, G. Maya-Núñez, 2002, The Journal of clinical endocrinology and metabolism.

Mutations in G protein-coupled receptors that impact receptor trafficking and reproductive function

P. Conn, J. Dias, A. Ulloa-Aguirre, 2014, Molecular and Cellular Endocrinology.

Therapeutic rescue of misfolded/mistrafficked mutants: automation-friendly high-throughput assays for identification of pharmacoperone drugs of GPCRs.

J. Janovick, David C. Smithson, P. M. Conn, 2013, Methods in enzymology.