Pavel Moudry

发表

Tumors overexpressing RNF168 show altered DNA repair and responses to genotoxic treatments, genomic instability and resistance to proteotoxic stress

J. Bartek, J. Bártková, R. Strauss, 2017, Oncogene.

Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage

J. Bartek, J. Lukas, C. Lukas, 2012, Cell cycle.

High speed of fork progression induces DNA replication stress and genomic instability

J. Bartek, A. Maya-Mendoza, J. Merchut-Maya, 2018, Nature.

Impaired ribosome biogenesis: mechanisms and relevance to cancer and aging

P. Moudry, M. Mistrik, M. Lacey, 2019, Aging.

Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells.

L. Varanasi, P. Džubák, P. Moudry, 2017, Journal of proteomics.

RNA-interference screen for p53 regulators unveils a role of WDR75 in ribosome biogenesis

J. Bartek, S. Volarevic, P. Moudry, 2021, Cell Death & Differentiation.

Perturbation of RNA Polymerase I transcription machinery by ablation of HEATR1 triggers the RPL5/RPL11-MDM2-p53 ribosome biogenesis stress checkpoint pathway in human cells

J. Bartek, P. Moudry, M. Mistrik, 2018, Cell cycle.

TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity

J. Lukas, J. Bártková, A. Maya-Mendoza, 2016, The Journal of cell biology.

Autocrine VEGF–VEGFR2–Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth

Jiri Bartek, Qiulian Wu, Jeremy N. Rich, 2012, The Journal of experimental medicine.

Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1

J. Ellenberg, R. Pepperkok, B. Neumann, 2011, Cell Death and Differentiation.

TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity TOP BP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity

J. Lukas, J. Bártková, A. Maya-Mendoza, 2016 .

A drug repurposing strategy for overcoming human multiple myeloma resistance to standard-of-care treatment

J. Bartek, P. Moudry, J. Gursky, 2022, Cell Death & Disease.

Bacterial intoxication evokes cellular senescence with persistent DNA damage and cytokine signalling

J. Bartek, T. Frisan, Z. Hodny, 2009, Journal of cellular and molecular medicine.

Alcohol-abuse drug disulfiram targets cancer via p97 segregase adapter NPL4

Jiri Bartek, Klaus Kaae Andersen, Jørgen Olsen, 2017, Nature.

Autocrine VEGF-VEGFR2—Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth

Qiulian Wu, J. Bartek, J. Lukas, 2012 .