Takehiko Ishii

发表

Impact of polyplex micelles installed with cyclic RGD peptide as ligand on gene delivery to vascular lesions

T. Shimada, K. Kataoka, T. Takato, 2011, Gene Therapy.

Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain

Y. Anraku, K. Toh, Y. Matsumoto, 2017, Nature Communications.

PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive nonviral gene vectors.

Yuichi Yamasaki, Kazunori Kataoka, Nobuhiro Nishiyama, 2008, Journal of the American Chemical Society.

New Synthesis of Heterobifunctional Poly(ethylene glycol) Possessing a Pyridyl Disulfide at One End and a Carboxylic Acid at the Other End

Y. Nagasaki, T. Ishii, Masayoshi Yamada, 2005 .

Charge-conversion ternary polyplex with endosome disruption moiety: a technique for efficient and safe gene delivery.

Muri Han, S. Fukushima, N. Nishiyama, 2008, Angewandte Chemie.

Glucose transporter 1‐mediated vascular translocation of nanomedicines enhances accumulation and efficacy in solid tumors

H. Saya, O. Nagano, Y. Anraku, 2019, Journal of controlled release : official journal of the Controlled Release Society.

Selective intracellular delivery of proteasome inhibitors through pH-sensitive polymeric micelles directed to efficient antitumor therapy.

K. Toh, N. Nishiyama, K. Kataoka, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Enhanced stability and gene silencing ability of siRNA-loaded polyion complexes formulated from polyaspartamide derivatives with a repetitive array of amino groups in the side chain.

N. Nishiyama, K. Kataoka, K. Itaka, 2012, Biomaterials.

A synthetic approach toward a self-regulated insulin delivery system.

Akira Matsumoto, Yuji Miyahara, Kazunori Kataoka, 2012, Angewandte Chemie.

Polyplex micelles prepared from ω-cholesteryl PEG-polycation block copolymers for systemic gene delivery.

S. Fukushima, M. Kano, N. Nishiyama, 2011, Biomaterials.

Polyplex Micelles with Phenylboronate/Gluconamide Cross-Linking in the Core Exerting Promoted Gene Transfection through Spatiotemporal Responsivity to Intracellular pH and ATP Concentration.

K. Kataoka, S. Uchida, H. Cabral, 2017, Journal of the American Chemical Society.

Phenylboronic acid-installed polymeric micelles for targeting sialylated epitopes in solid tumors.

Y. Miyahara, N. Nishiyama, K. Kataoka, 2013, Journal of the American Chemical Society.

A phenylboronate-functionalized polyion complex micelle for ATP-triggered release of siRNA.

Akira Matsumoto, Yuji Miyahara, Kazunori Kataoka, 2012, Angewandte Chemie.

Enhanced Intracellular Delivery of siRNA by Controlling ATP-Responsivity of Phenylboronic Acid-Functionalized Polyion Complex Micelles.

Y. Miyahara, K. Kataoka, K. Miyata, 2018, Macromolecular bioscience.

Intratracheal gene transfer of adrenomedullin using polyplex nanomicelles attenuates monocrotaline-induced pulmonary hypertension in rats.

N. Nishiyama, K. Kataoka, K. Itaka, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

Copolymers including L-histidine and hydrophobic moiety for preparation of nonbiofouling surface.

M. Casolaro, Yoshihiro Ito, T. Ishii, 2007, Biomacromolecules.

Effective transgene expression without toxicity by intraperitoneal administration of PEG-detachable polyplex micelles in mice with peritoneal dissemination.

N. Nishiyama, K. Kataoka, K. Itaka, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Intracellular Delivery of Charge-Converted Monoclonal Antibodies by Combinatorial Design of Block/Homo Polyion Complex Micelles.

N. Nishiyama, K. Kataoka, H. Cabral, 2016, Biomacromolecules.

Charge-conversional polyionic complex micelles-efficient nanocarriers for protein delivery into cytoplasm.

N. Nishiyama, K. Kataoka, Yan Lee, 2009, Angewandte Chemie.

Smart PEGylated Gold Nanoparticles for the Cytoplasmic Delivery of siRNA to Induce Enhanced Gene Silencing

Yukio Nagasaki, Y. Nagasaki, T. Ishii, 2006 .

Development of Biodegradable Polycation-Based Inhalable Dry Gene Powders by Spray Freeze Drying

K. Kataoka, Yuko Kobayashi, K. Itaka, 2015, Pharmaceutics.

Multifunctional polyion complex micelle featuring enhanced stability, targetability, and endosome escapability for systemic siRNA delivery to subcutaneous model of lung cancer

K. Toh, Y. Matsumoto, N. Nishiyama, 2013, Drug Delivery and Translational Research.

Acidic pH-responsive siRNA conjugate for reversible carrier stability and accelerated endosomal escape with reduced IFNα-associated immune response.

N. Nishiyama, K. Kataoka, S. Uchida, 2013, Angewandte Chemie.

cRGD peptide‐installed epirubicin‐loaded polymeric micelles for effective targeted therapy against brain tumors

N. Nishiyama, K. Kataoka, H. Cabral, 2017, Journal of controlled release : official journal of the Controlled Release Society.

Muscle-targeted hydrodynamic gene introduction of insulin-like growth factor-1 using polyplex nanomicelle to treat peripheral nerve injury.

K. Kataoka, K. Itaka, S. Uchida, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Modulated protonation of side chain aminoethylene repeats in N-substituted polyaspartamides promotes mRNA transfection.

Takahiro Nomoto, N. Nishiyama, K. Kataoka, 2014, Journal of the American Chemical Society.

Dual environment-responsive polyplex carriers for enhanced intracellular delivery of plasmid DNA.

N. Nishiyama, K. Kataoka, K. Miyata, 2012, Biomacromolecules.

Odd-even effect of repeating aminoethylene units in the side chain of N-substituted polyaspartamides on gene transfection profiles.

N. Nishiyama, K. Kataoka, K. Itaka, 2011, Journal of the American Chemical Society.

Polyion complex stability and gene silencing efficiency with a siRNA-grafted polymer delivery system.

N. Nishiyama, K. Kataoka, Y. Yamasaki, 2010, Biomaterials.

pDNA/poly(L-lysine) Polyplexes Functionalized with a pH-Sensitive Charge-Conversional Poly(aspartamide) Derivative for Controlled Gene Delivery to Human Umbilical Vein Endothelial Cells.

K. Kataoka, Yan Lee, K. Miyata, 2010, Macromolecular rapid communications.

Enhanced endosomal escape of siRNA-incorporating hybrid nanoparticles from calcium phosphate and PEG-block charge-conversional polymer for efficient gene knockdown with negligible cytotoxicity.

N. Nishiyama, K. Kataoka, Yan Lee, 2011, Biomaterials.

Messenger RNA-based therapeutics for the treatment of apoptosis-associated diseases

K. Kataoka, K. Itaka, S. Uchida, 2015, Scientific Reports.

In Vivo Messenger RNA Introduction into the Central Nervous System Using Polyplex Nanomicelle

S. Fukushima, K. Kataoka, K. Itaka, 2013, PloS one.

Enhanced target recognition of nanoparticles by cocktail PEGylation with chains of varying lengths.

Y. Anraku, K. Kataoka, K. Miyata, 2016, Chemical Communications.

Efficient delivery of bioactive antibodies into the cytoplasm of living cells by charge-conversional polyion complex micelles.

N. Nishiyama, K. Kataoka, K. Itaka, 2010, Angewandte Chemie.

The initiatives for regulatory science researches of nanomedicines

Yasuhiro Matsumura, Kazunori Kataoka, Harashima Hideyoshi, 2014 .

Accelerated polymer-polymer click conjugation by freeze-thaw treatment.

N. Nishiyama, K. Kataoka, K. Miyata, 2012, Bioconjugate chemistry.

Smart multilayered assembly for biocompatible siRNA delivery featuring dissolvable silica, endosome-disrupting polycation, and detachable PEG.

Y. Anraku, N. Nishiyama, K. Kataoka, 2012, ACS nano.

Gene Transfer Using Micellar Nanovectors Inhibits Choroidal Neovascularization In Vivo

N. Nishiyama, K. Kataoka, M. Oba, 2011, PloS one.

PEGylated Calcium Phosphate Nanocomposites as Smart Environment‐Sensitive Carriers for siRNA Delivery

Yuichi Yamasaki, Kazunori Kataoka, Nobuhiro Nishiyama, 2009 .

An injectable spheroid system with genetic modification for cell transplantation therapy.

Yu Matsumoto, Satoshi Uchida, Kazunori Kataoka, 2014, Biomaterials.

One-Pot Synthesis of pH-Responsive PEGylated Nanogels Containing Gold Nanoparticles by Autoreduction of Chloroaurate Ions within Nanoreactors

Y. Nagasaki, T. Ishii, M. Oishi, 2007 .

A protein nanocarrier from charge-conversion polymer in response to endosomal pH.

Kazunori Kataoka, S. Fukushima, K. Kataoka, 2007, Journal of the American Chemical Society.

Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors.

Takahiro Nomoto, K. Toh, Y. Matsumoto, 2014, Biomaterials.

Preparation of functionally Pegylated gold nanoparticles with narrow distribution through autoreduction of auric cation by alpha-biotinyl-PEG-block-[poly(2- (N,N-dimethylamino)ethyl methacrylate)].

Kazunori Kataoka, Yukio Nagasaki, Hidenori Otsuka, 2004, Langmuir : the ACS journal of surfaces and colloids.

Gene Transfection toward Spheroid Cells on Micropatterned Culture Plates for Genetically-modified Cell Transplantation.

K. Kataoka, K. Itaka, S. Uchida, 2015, Journal of visualized experiments : JoVE.

Polyplex Micelles with Double-Protective Compartments of Hydrophilic Shell and Thermoswitchable Palisade of Poly(oxazoline)-Based Block Copolymers for Promoted Gene Transfection.

K. Kataoka, K. Osada, A. Dirisala, 2016, Biomacromolecules.

Homo-catiomer integration into PEGylated polyplex micelle from block-catiomer for systemic anti-angiogenic gene therapy for fibrotic pancreatic tumors.

M. Kano, K. Kataoka, K. Itaka, 2012, Biomaterials.

PEGylated polyplex with optimized PEG shielding enhances gene introduction in lungs by minimizing inflammatory responses.

K. Kataoka, K. Itaka, S. Uchida, 2012, Molecular therapy : the journal of the American Society of Gene Therapy.