Cristiano Noto

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A Study in First-Episode Psychosis Patients: Does Angiotensin I-Converting Enzyme Activity Associated With Genotype Predict Symptom Severity Reductions After Treatment With Atypical Antipsychotic Risperidone?

A. Gadelha, C. Noto, Q. Cordeiro, 2020, The international journal of neuropsychopharmacology.

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Michael F. Green, Max W. Y. Lam, Catherine A. Sugar, 2022, Nature.

Gene expression alterations related to mania and psychosis in peripheral blood of patients with a first episode of psychosis

J. Sato, A. Gadelha, C. Noto, 2016, Translational psychiatry.

The role of oxidative and nitrosative stress in accelerated aging and major depressive disorder

Cristiano Noto, Pawan Kumar Maurya, Rodrigo B. Mansur, 2016, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Determinants of adherence to treatment in first-episode psychosis: a comprehensive review.

C. Noto, R. Bressan, E. Brietzke, 2015, Revista brasileira de psiquiatria.

Impairments in Peripheral Blood T Effector and T Regulatory Lymphocytes in Bipolar Disorder Are Associated with Staging of Illness and Anti-cytomegalovirus IgG Levels

M. Maes, C. Noto, L. Rizzo, 2020, Molecular Neurobiology.

Depression, Cytokine, and Cytokine by Treatment Interactions Modulate Gene Expression in Antipsychotic Naïve First Episode Psychosis

M. Maes, A. Gadelha, C. Noto, 2015, Molecular Neurobiology.

Targeting the Inflammatory Pathway as a Therapeutic Tool for Major Depression

M. Maes, R. McIntyre, C. Noto, 2014, Neuroimmunomodulation.

Major Depression: An Immune-Inflammatory Disorder

M. Maes, C. Noto, L. Rizzo, 2015 .

Physio-somatic symptoms in schizophrenia: association with depression, anxiety, neurocognitive deficits and the tryptophan catabolite pathway

M. Geffard, A. Carvalho, K. Ruxrungtham, 2017, Metabolic Brain Disease.

Evaluation of the efficacy of transcranial direct current stimulation in the treatment of cognitive symptomatology in the early stages of psychosis: study protocol for a double-blind randomized controlled trial

A. Gadelha, C. Noto, Q. Cordeiro, 2019, Trials.

Differences of affective and non-affective psychoses in early intervention services from Latin America.

N. Crossley, C. López-Jaramillo, A. Gadelha, 2022, Journal of affective disorders.

Longitudinal invariance of the positive and negative syndrome scale negative dimension in antipsychotic naïve first‐episode schizophrenia

A. Gadelha, C. Noto, Q. Cordeiro, 2021, Early intervention in psychiatry.

Impact of duration of untreated psychosis in short‐term response to treatment and outcome in antipsychotic naïve first‐episode psychosis

A. Gadelha, C. Noto, Q. Cordeiro, 2020, Early intervention in psychiatry.

Patients with Schizophrenia Undergoing Gastric Bypass Surgery: a Case Series Study

L. Velloso, A. Gadelha, C. Noto, 2020, Obesity Surgery.

A symptom combination predicting treatment-resistant schizophrenia – A strategy for real-world clinical practice

D. Joyce, C. Correll, A. Gadelha, 2020, Schizophrenia Research.

Cannabis acute use impacts symptoms and functionality in a cohort of antipsychotic naïve First Episode of Psychosis individuals

A. Gadelha, C. Noto, Q. Cordeiro, 2019, Schizophrenia Research: Cognition.

Activation of the immune-inflammatory response system and the compensatory immune-regulatory system in antipsychotic naive first episode psychosis

C. Noto, M. Noto, Michael Maes, 2019, European Neuropsychopharmacology.

New evidence in support of staging approaches in schizophrenia: Differences in clinical profiles between first episode, early stage, and late stage.

A. Gadelha, C. Noto, R. Bressan, 2017, Comprehensive psychiatry.

Psychosis in Machado–Joseph Disease: Clinical Correlates, Pathophysiological Discussion, and Functional Brain Imaging. Expanding the Cerebellar Cognitive Affective Syndrome

A. Gadelha, C. Noto, J. Pedroso, 2016, The Cerebellum.

Serum brain-derived neurotrophic factor and cortical thickness are differently related in patients with schizophrenia and controls

P. McGuire, M. Kempton, A. Gadelha, 2015, Psychiatry Research: Neuroimaging.

Oxidative stress in drug naïve first episode psychosis and antioxidant effects of risperidone.

M. Maes, A. Gadelha, C. Noto, 2015, Journal of psychiatric research.

Lowered paraoxonase 1 (PON1) activity is associated with increased cytokine levels in drug naïve first episode psychosis

M. Maes, A. Gadelha, C. Noto, 2015, Schizophrenia Research.

Effects of depression on the cytokine profile in drug naïve first-episode psychosis

A. Gadelha, C. Noto, Q. Cordeiro, 2015, Schizophrenia Research.

Effects of Risperidone on Cytokine Profile in Drug-Naïve First-Episode Psychosis

M. Maes, A. Gadelha, C. Noto, 2015, The international journal of neuropsychopharmacology.

What are the PANSS items most related with global improvements in patients with schizophrenia? Toward a reduced version of the PANSS

A. Gadelha, C. Noto, R. Bressan, 2014, Schizophrenia Research.

Evaluation of neurotransmitter receptor gene expression identifies GABA receptor changes: a follow-up study in antipsychotic-naïve patients with first-episode psychosis.

J. Sato, A. Gadelha, C. Noto, 2014, Journal of psychiatric research.

Factor structure of the Positive and Negative Syndrome Scale (PANSS) in Brazil: convergent validation of the Brazilian version.

A. Gadelha, C. Noto, Q. Cordeiro, 2014, Revista brasileira de psiquiatria.

Toward Omics-Based, Systems Biomedicine, and Path and Drug Discovery Methodologies for Depression-Inflammation Research

J. Leza, R. Balling, E. Glaab, 2015, Molecular Neurobiology.

Using deep belief network modelling to characterize differences in brain morphometry in schizophrenia

J. Sato, W. H. Pinaya, A. Gadelha, 2016, Scientific Reports.

The Role of Aberrations in the Immune-Inflammatory Response System (IRS) and the Compensatory Immune-Regulatory Reflex System (CIRS) in Different Phenotypes of Schizophrenia: the IRS-CIRS Theory of Schizophrenia

M. Maes, A. Carvalho, M. Kubera, 2018, Molecular Neurobiology.

First Episode Psychosis and Schizophrenia Are Systemic Neuro-Immune Disorders Triggered by a Biotic Stimulus in Individuals with Reduced Immune Regulation and Neuroprotection

K. Plaimas, C. Noto, A. Suratanee, 2021, Cells.

Pharmacological and Psychosocial Management of Mental, Neurological and Substance Use Disorders in Low- and Middle-Income Countries: Issues and Current Strategies

C. Noto, J. J. Jesus Mari, Mario F. Juruena, 2013, Drugs.

Clozapine prescription trends in Brazil in the last decade

A. Gadelha, C. Noto, R. Bressan, 2022, Revista brasileira de psiquiatria.

The role of aberrations in the immune-inflammatory reflex system (IRS) and the compensatory immune-regulatory reflex system (CIRS) in different phenotypes of schizophrenia: the IRS-CIRS theory of schizophrenia Short title: The IRS-CIRS theory of schizophrenia

A. Carvalho, C. Noto, M. Kubera, 2018 .

Association of biomarkers and depressive symptoms in schizophrenia

A. Gadelha, C. Noto, R. Bressan, 2011, Neuroscience Letters.

Investigating brain structural patterns in first episode psychosis and schizophrenia using MRI and a machine learning approach

J. Sato, W. H. Pinaya, A. Gadelha, 2018, Psychiatry Research: Neuroimaging.

Accessing Gene Expression in Treatment-Resistant Schizophrenia

A. Gadelha, C. Noto, R. Bressan, 2018, Molecular Neurobiology.

Gene expression analysis in blood of ultra-high risk subjects compared to first-episode of psychosis patients and controls

P. Pan, A. Gadelha, C. Noto, 2015, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

BDNF in antipsychotic naive first episode psychosis: Effects of risperidone and the immune-inflammatory response system.

A. Gadelha, C. Noto, Q. Cordeiro, 2021, Journal of psychiatric research.

Polygenic risk score analyses of symptoms and treatment response in an antipsychotic-naive first episode of psychosis cohort

G. Breen, S. Newhouse, C. Curtis, 2018, Translational Psychiatry.

Structural covariance in schizophrenia and first-episode psychosis: An approach based on graph analysis.

P. McGuire, N. Crossley, J. Sato, 2015, Journal of psychiatric research.

Aging biological markers in a cohort of antipsychotic-naïve first-episode psychosis patients

G. Breen, P. Maurya, A. Gadelha, 2021, Psychoneuroendocrinology.

Angiotensin converting enzyme activity is positively associated with IL-17a levels in patients with schizophrenia

M. Maes, A. Gadelha, C. Noto, 2015, Psychiatry Research.

Leukocyte telomere length variation in different stages of schizophrenia.

M. Maes, P. Maurya, A. Gadelha, 2018, Journal of psychiatric research.

High predictive value of immune-inflammatory biomarkers for schizophrenia diagnosis and association with treatment resistance

M. Maes, A. Gadelha, R. Bressan, 2015, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

Changes in gene expression and methylation in the blood of patients with first-episode psychosis

J. Sato, A. Gadelha, C. Noto, 2014, Schizophrenia Research.

Omics-based depression and inflammation research.

M. Maes, E. Brietzke, Cristiano Noto, 2015, Revista brasileira de psiquiatria.

Ndel1 oligopeptidase activity as a potential biomarker of early stages of schizophrenia

A. Gadelha, C. Noto, Q. Cordeiro, 2019, Schizophrenia Research.

Systems-Level Analysis of Genetic Variants Reveals Functional and Spatiotemporal Context in Treatment-resistant Schizophrenia

A. Gadelha, C. Noto, R. Bressan, 2022, Molecular Neurobiology.

Clinical characteristics and influence of childhood trauma on the prodrome of bipolar disorder.

C. Correll, R. Grassi‐Oliveira, M. Noto, 2015, Revista brasileira de psiquiatria.

Structural brain abnormalities in schizophrenia in adverse environments: examining the effect of poverty and violence in six Latin American cities

Juan P. Ramirez-Mahaluf, N. Crossley, S. Guinjoan, 2020, The British Journal of Psychiatry.

GAPi: A description of the initiative for early psychosis intervention in Latin America and the short- to medium-term outcomes in early psychosis patients.

A. Gadelha, Q. Cordeiro, M. Noto, 2024, Asian journal of psychiatry.

The Feuerstein Instrumental Enrichment for People with Schizophrenia after the First Episode Psychosis: a research protocol for open label intervention study. (Preprint)

A. Gadelha, J. Gomes, Cristiano Noto, 2024, JMIR Research Protocols.

Gene expression over the course of schizophrenia: from clinical high-risk for psychosis to chronic stages

H. Hakonarson, G. Breen, S. de Jong, 2019, npj Schizophrenia.

COVID-19 pandemic and distinct patterns of psychotic outbreaks

A. Gadelha, C. Noto, C. G. Costardi, 2021, Trends in psychiatry and psychotherapy.

Pharmacological treatment of schizophrenia

J. de Jesus Mari, A. Gadelha, C. Noto, 2012, International review of psychiatry.

Circulating levels of sTNFR1 as a marker of severe clinical course in schizophrenia.

J. de Jesus Mari, A. Gadelha, C. Noto, 2013, Journal of psychiatric research.

Impact of peripheral levels of chemokines, BDNF and oxidative markers on cognition in individuals with schizophrenia.

A. Gadelha, C. Noto, A. Zugman, 2013, Journal of psychiatric research.

Increased expression of NDEL1 and MBP genes in the peripheral blood of antipsychotic-naïve patients with first-episode psychosis

A. Gadelha, C. Noto, Q. Cordeiro, 2015, European Neuropsychopharmacology.

Catechol-O-methyltransferase (COMT) polymorphisms modulate working memory in individuals with schizophrenia and healthy controls

A. Gadelha, C. Noto, M. I. Melaragno, 2017, Revista brasileira de psiquiatria.

LINE-1 hypomethylation is associated with poor risperidone response in a first episode of psychosis cohort.

A. Gadelha, C. Noto, Q. Cordeiro, 2020, Epigenomics.

Oxidative and nitrosative stress biomarkers in chronic schizophrenia

A. Gadelha, R. Bressan, C. Bortolasci, 2017, Psychiatry Research.