Johanna E. Fraser

A nuclear transport inhibitor that modulates the unfolded protein response and provides in vivo protection against lethal dengue virus infection.

P. Sexton, S. Vasudevan, D. Jans, 2014, The Journal of infectious diseases.

Nuclear localization of dengue virus (DENV) 1-4 non-structural protein 5; protection against all 4 DENV serotypes by the inhibitor Ivermectin.

Moon Y. F. Tay, S. Vasudevan, M. Y. Tay, 2013, Antiviral research.

Novel dengue virus inhibitor 4-HPR activates ATF4 independent of protein kinase R-like Endoplasmic Reticulum Kinase and elevates levels of eIF2α phosphorylation in virus infected cells.

S. Vasudevan, D. Jans, J. Fraser, 2016, Antiviral research.

High Throughput Screening Targeting the Dengue NS3-NS5 Interface Identifies Antivirals against Dengue, Zika and West Nile Viruses

D. Jans, Chunxiao Wang, J. Fraser, 2022, Cells.

Transient Introgression of Wolbachia into Aedes aegypti Populations Does Not Elicit an Antibody Response to Wolbachia Surface Protein in Community Members

C. Simmons, Heather A. Flores, J. Fraser, 2022, Pathogens.

Novel Flavivirus Antiviral That Targets the Host Nuclear Transport Importin α/β1 Heterodimer

J. Forwood, N. Borg, D. Jans, 2019, Cells.

Investigating dengue virus nonstructural protein 5 (NS5) nuclear import.

D. Jans, Chunxiao Wang, J. Fraser, 2014, Methods in molecular biology.