Barbara C Mcgrath

发表

Genetic connectivity and population structure of African savanna elephants (Loxodonta africana) in Tanzania

Barbara C. McGrath, D. Cavener, A. Estes, 2020, Ecology and evolution.

PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis.

Barbara C. McGrath, D. Cavener, Wei Zhang, 2006, Cell metabolism.

Phosphorylation of the α Subunit of Eukaryotic Initiation Factor 2 Is Required for Activation of NF-κB in Response to Diverse Cellular Stresses

D. Scheuner, R. Kaufman, R. Wek, 2003, Molecular and Cellular Biology.

The PERK Eukaryotic Initiation Factor 2α Kinase Is Required for the Development of the Skeletal System, Postnatal Growth, and the Function and Viability of the Pancreas

Peichuan Zhang, Barbara C. McGrath, Jamie Reinert, 2002, Molecular and Cellular Biology.

The protein kinase PERK/EIF2AK3 regulates proinsulin processing not via protein synthesis but by controlling endoplasmic reticulum chaperones

Barbara C. McGrath, D. Cavener, M. Nicolino, 2018, The Journal of Biological Chemistry.

The Combined Effects of Tryptophan Starvation and Tryptophan Catabolites Down-Regulate T Cell Receptor ζ-Chain and Induce a Regulatory Phenotype in Naive T Cells1

U. Grohmann, M. L. Belladonna, C. Orabona, 2006, The Journal of Immunology.

Activating Transcription Factor 3 Is Integral to the Eukaryotic Initiation Factor 2 Kinase Stress Response

Tsonwin Hai, Xiaozhong Wang, D. Ron, 2004, Molecular and Cellular Biology.

The GCN2 eIF2α Kinase Is Required for Adaptation to Amino Acid Deprivation in Mice

S. Kimball, L. Jefferson, R. Wek, 2002, Molecular and Cellular Biology.

Giraffe genome sequence reveals clues to its unique morphology and physiology

W. Miller, C. Praul, R. Chikhi, 2016, Nature Communications.

Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-kappaB in response to diverse cellular stresses.

D. Scheuner, R. Kaufman, R. Wek, 2003, Molecular and cellular biology.

PERK is responsible for the increased phosphorylation of eIF2α and the severe inhibition of protein synthesis after transient global brain ischemia

Rita Kumar, G. Krause, Peichuan Zhang, 2005, Journal of neurochemistry.

PERK in beta cell biology and insulin biogenesis

Sounak Gupta, Barbara C. McGrath, D. Cavener, 2010, Trends in Endocrinology & Metabolism.

Insulin Secretion and Ca2+ Dynamics in β-Cells Are Regulated by PERK (EIF2AK3) in Concert with Calcineurin*

Barbara C. McGrath, D. Cavener, R. Kopp, 2013, The Journal of Biological Chemistry.

PERK regulates insulin secretion and Ca 2 + dynamics 1 Insulin secretion and Ca 2 + dynamics in β-cells are regulated by PERK eIF 2 α kinase in concert with calcineurin

Barbara C. McGrath, D. Cavener, R. Kopp, 2013 .

Uncharged tRNA and Sensing of Amino Acid Deficiency in Mammalian Piriform Cortex

T. Anthony, R. Wek, Barbara C. McGrath, 2005, Science.

Preservation of Liver Protein Synthesis during Dietary Leucine Deprivation Occurs at the Expense of Skeletal Muscle Mass in Mice Deleted for eIF2 Kinase GCN2*

T. Anthony, M. McNurlan, R. Wek, 2004, Journal of Biological Chemistry.

Hyperthermia Induces the ER Stress Pathway

Sounak Gupta, Barbara C. McGrath, D. Cavener, 2011, PloS one.

PERK (eIF2alpha kinase) is required to activate the stress-activated MAPKs and induce the expression of immediate-early genes upon disruption of ER calcium homoeostasis.

Wei Zhang, S. Liang, Peichuan Zhang, 2006, The Biochemical journal.

PERK (EIF2AK3) Regulates Proinsulin Trafficking and Quality Control in the Secretory Pathway

Sounak Gupta, Barbara C. McGrath, D. Cavener, 2010, Diabetes.

PERK is essential for neonatal skeletal development to regulate osteoblast proliferation and differentiation

Barbara C. McGrath, D. Cavener, Daorong Feng, 2008, Journal of cellular physiology.

Induce a Regulatory Phenotype in Naive T-Chain and ζ DownRegulate T Cell Receptor Starvation and Tryptophan Catabolites The Combined Effects of Tryptophan Puccetti

U. Grohmann, M. L. Belladonna, C. Orabona, 2006 .

PERK eIF2 alpha kinase is required to regulate the viability of the exocrine pancreas in mice

Barbara C. McGrath, D. Cavener, Yulin Li, 2007, BMC Cell Biology.

PERK regulates Gq protein-coupled intracellular Ca2+ dynamics in primary cortical neurons

Barbara C. McGrath, D. Cavener, Siying Zhu, 2016, Molecular Brain.

PERK Regulates the Proliferation and Development of Insulin-Secreting Beta-Cell Tumors in the Endocrine Pancreas of Mice

Sounak Gupta, Barbara C. McGrath, D. Cavener, 2009, PloS one.

Co-opting regulation bypass repair as a gene-correction strategy for monogenic diseases

Barbara C. McGrath, D. Cavener, Jingjie Hu, 2020, Molecular therapy : the journal of the American Society of Gene Therapy.

Acute ablation of PERK results in ER dysfunctions followed by reduced insulin secretion and cell proliferation

Sounak Gupta, Barbara C. McGrath, D. Cavener, 2009, BMC Cell Biology.

Perk Gene Dosage Regulates Glucose Homeostasis by Modulating Pancreatic β-Cell Functions

Barbara C. McGrath, D. Cavener, Siying Zhu, 2014, PloS one.