Ian Bytheway

发表

Discovery of PG545: a highly potent and simultaneous inhibitor of angiogenesis, tumor growth, and metastasis.

N. Wimmer, E. Hammond, P. Handley, 2012, Journal of medicinal chemistry.

PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models

T. Gonda, R. Brandt, Maree T. Smith, 2011, British Journal of Cancer.

Theoretical Calculations of Metal-Dioxygen Complexes

Michael B. Hall, Ian Bytheway, M. Hall, 1994 .

The mathematical modelling of cluster geometry

Ian Bytheway, I. Bytheway, David L. Kepert, 1992 .

Design, synthesis, FGF-1 binding, and molecular modeling studies of conformationally flexible heparin mimetic disaccharides.

I. Bytheway, T. Karoli, S. Cochran, 2008, Bioorganic & medicinal chemistry letters.

Wavefunctions derived from experiment. III. Topological analysis of crystal fragments.

D. Jayatilaka, I. Bytheway, D. Grimwood, 2002, Acta crystallographica. Section A, Foundations of crystallography.

Polyamine-based small molecule epigenetic modulators.

Shiv k. Sharma, F. Hirata, Yi Huang, 2012, MedChemComm.

Validation of molecular docking calculations involving FGF-1 and FGF-2.

I. Bytheway, S. Cochran, Ian Bytheway, 2004, Journal of medicinal chemistry.

Synthesis of a heparan sulfate mimetic disaccharide with a conformationally locked residue from a common intermediate.

I. Bytheway, T. Karoli, V. Ferro, 2009, Carbohydrate research.

Mechanisms of heparanase inhibition by the heparan sulfate mimetic PG545 and three structural analogues☆

E. Hammond, P. Handley, K. Dredge, 2013, FEBS open bio.

Synthesis and biological evaluation of polysulfated oligosaccharide glycosides as inhibitors of angiogenesis and tumor growth.

David M. Shackleford, T. Gonda, S. Charman, 2010, Journal of medicinal chemistry.

The polyamine analog PG11047 potentiates the antitumor activity of cisplatin and bevacizumab in preclinical models of lung and prostate cancer

L. Marton, R. Johnson, K. Dredge, 2009, Cancer Chemotherapy and Pharmacology.

PI-88 and novel heparan sulfate mimetics inhibit angiogenesis.

E. Hammond, K. Dredge, I. Bytheway, 2007, Seminars in thrombosis and hemostasis.

Wave functions derived from experiment. V. Investigation of electron densities, electrostatic potentials, and electron localization functions for noncentrosymmetric crystals

Daniel J. Grimwood, Ian Bytheway, Dylan Jayatilaka, 2003, J. Comput. Chem..

The PG500 series: novel heparan sulfate mimetics as potent angiogenesis and heparanase inhibitors for cancer therapy

T. Gonda, N. Wimmer, E. Hammond, 2010, Investigational New Drugs.

Cluster Chemistry: LIX. Stereochemistry of group 15 ligand-substituted derivatives of M3(CO)12 (M = Ru, Os). D. Synthesis and characterisation of some tetra-substituted ruthenium complexes: X-ray structures of Ru3(CO)8(L)4 (L = PMe2Ph and P(OR)3, R = Me, Et and Ph)☆

M. Liddell, B. Skelton, A. White, 1989 .