J. R. Bertino

发表

Molecular mechanisms of resistance to antifolates, a review.

M. Waltham, E. Ercikan-Abali, D. Banerjee, 1995, Acta biochimica Polonica.

Sequence-dependent enhancement of cytotoxicity produced by ecteinascidin 743 (ET-743) with doxorubicin or paclitaxel in soft tissue sarcoma cells.

D. Banerjee, J. Bertino, K. Scotto, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Basis for natural resistance to methotrexate in human acute non-lymphocytic leukemia.

B. Schweitzer, J. Bertino, D. Niedzwiecki, 1991, Leukemia research.

Defective transport is a common mechanism of acquired methotrexate resistance in acute lymphocytic leukemia and is associated with decreased reduced folate carrier expression.

M. Mazumdar, J. Bertino, P. Steinherz, 1997, Blood.

Modulation of cytotoxicity of chemotherapeutic drugs by activated H-ras.

D. Banerjee, J. Bertino, P. Stambrook, 1997, Biochemical pharmacology.

Defective transport as a mechanism of acquired resistance to methotrexate in patients with acute lymphocytic leukemia.

P. Steinherz, E. Berman, E. Goker, 1992, Blood.

Current understanding of methotrexate pharmacology and efficacy in acute leukemias. Use of newer antifolates in clinical trials.

Bertino, J. Bertino, G. Longo-Sorbello, 2001, Haematologica.

Levels of E2F-1 expression are higher in lung metastasis of colon cancer as compared with hepatic metastasis and correlate with levels of thymidylate synthase.

C. Cordon-Cardo, S. Jhanwar, D. Banerjee, 2000, Cancer research.

Inherent resistance of human squamous carcinoma cell lines to methotrexate as a result of decreased polyglutamylation of this drug.

J. Bertino, J. McGuire, G. Pizzorno, 1989, Cancer research.

Active site-directed double mutants of dihydrofolate reductase.

M. Waltham, E. Ercikan-Abali, S. Nakahara, 1996, Cancer research.

gamma-Glutamyl hydrolase and folylpolyglutamate synthetase activities predict polyglutamylation of methotrexate in acute leukemias.

J. Bertino, P. Steinherz, W. Tong, 1997, Oncology research.

Selective treatment of SCID mice bearing methotrexate-transport-resistant human acute lymphoblastic leukemia tumors with trimetrexate and leucovorin protection.

J. Bertino, E. Göker, E. Goker, 1995, Blood.

Cytotoxic effects of folate antagonists against methotrexate-resistant human leukemic lymphoblast CCRF-CEM cell lines.

J. Bertino, E. Mini, B. Moroson, 1985, Cancer research.

Resistance Mechanisms to Methotrexate in Tumors

D. Banerjee, J. Bertino, W. Li, 1996, Stem cells.