Christine F. Gelin

Discovery of a Series of Substituted 1H-((1,2,3-Triazol-4-yl)methoxy)pyrimidines as Brain Penetrants and Potent GluN2B-Selective Negative Allosteric Modulators.

C. Dvorak, N. Carruthers, J. Alcázar, 2023, Journal of medicinal chemistry.

A Dipolar Cycloaddition Reaction To Access 6-Methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridines Enables the Discovery Synthesis and Preclinical Profiling of a P2X7 Antagonist Clinical Candidate.

C. Dvorak, N. Carruthers, A. Bhattacharya, 2018, Journal of medicinal chemistry.

4-Methyl-6,7-dihydro-4H-triazolo[4,5-c]pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate.

P. Bonaventure, C. Dvorak, T. Lovenberg, 2017, Journal of medicinal chemistry.

Identification of small-molecule protein–protein interaction inhibitors for NKG2D

Jennifer D. Venable, J. Edwards, A. Thompson, 2023, Proceedings of the National Academy of Sciences of the United States of America.

Identification of a Novel Small Molecule HIF-1α Translation Inhibitor

Erwin G. Van Meir, C. Moreno, Shaoman Yin, 2009, Clinical Cancer Research.

Synthesis of the QRSTU domain of maitotoxin and its 85-epi- and 86-epi-diastereoisomers.

K. Nicolaou, J. Seo, Zhihong Huang, 2010, Journal of the American Chemical Society.

P2X7 receptor antagonists for the treatment of systemic inflammatory disorders.

A. Bhattacharya, Christine F Gelin, M. Letavic, 2020, Progress in medicinal chemistry.

Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement Pathway.

N. Gradoux, A. Vulpetti, B. Jaffee, 2019, Journal of medicinal chemistry.