Jan Balzarini

发表

The potential impact of drug transporters on nucleoside-analog-based antiviral chemotherapy.

P. Wielinga, N. Zelcer, J. Balzarinib, 2004, Antiviral research.

Cyclosaligenyl-2',3'-didehydro-2',3'-dideoxythymidine monophosphate: efficient intracellular delivery of d4TMP.

E. De Clercq, J. Balzarini, E. Clercq, 2000, Molecular pharmacology.

The potential impact of drug transporters on nucleoside-analog-based antiviral chemotherapy.

J. Wijnholds, P. Wielinga, G. Reid, 2004, Antiviral Research.

Intestinal absorption characteristics of the low solubility thiocarboxanilide UC-781.

E. De Clercq, L. Naesens, J. Balzarini, 2002, International journal of pharmaceutics.

Chemotherapy of varicella-zoster virus by a novel class of highly specific anti-VZV bicyclic pyrimidine nucleosides.

J. Balzarini, C. Mcguigan, C. Mcguigan*, 2002, Biochimica et biophysica acta.

Doubly homologated dihalovinyl and acetylene analogues of adenosine: synthesis, interaction with S-adenosyl-L-homocysteine hydrolase, and antiviral and cytostatic effects.

E. De Clercq, R. Borchardt, C. A. Valdez, 2000, Journal of medicinal chemistry.

Spectroscopic and biological properties of palladium(II) complexes of ethyl 2-quinolylmethylphosphonate.

E. De Clercq, J. Balzarini, L. Tušek-Boz̆ić, 1998, Journal of inorganic biochemistry.

Broad-Spectrum Antiviral Activity and Mechanism of Antiviral Action of the Fluoroquinolone Derivative K-12

E. De Clercq, C. Pannecouque, A. Vandamme, 1998, Antiviral chemistry & chemotherapy.

Patient HIV-1 strains carrying the multiple nucleoside resistance mutations are cross-resistant to abacavir.

E. De Clercq, T. Harrer, B. Clotet, 2000, AIDS.

Synthesis and evaluation of novel amidate prodrugs of PMEA and PMPA.

E. De Clercq, J. Balzarini, E. Clercq, 2001, Bioorganic & medicinal chemistry letters.

Anti-retrovirus activity of 3'-fluoro- and 3'-azido-substituted pyrimidine 2',3'-dideoxynucleoside analogues.

R. Pauwels, P. Herdewijn, M. Baba, 1988, Biochemical pharmacology.

Antiretrovirus Activity of a Novel Class of Acyclic Pyrimidine Nucleoside Phosphonates

E. De Clercq, C. Pannecouque, C. Perno, 2002, Antimicrobial Agents and Chemotherapy.

Mutation of Gln125 to Asn selectively abolishes the thymidylate kinase activity of herpes simplex virus type 1 thymidine kinase.

R. Esnouf, E. De Clercq, B. Degrève, 2001, Molecular pharmacology.

Bystander effect of purine nucleoside analogues in HSV-1tk suicide gene therapy is superior to that of pyrimidine nucleoside analogues

B. Degrève, J. Balzarini, E. D. Clercq, 1999, Gene Therapy.

Synthesis and antiherpes virus activity of 1,5-anhydrohexitol nucleosides.

E. De Clercq, P. Herdewijn, G. Janssen, 1993, Journal of medicinal chemistry.

Particular characteristics of the anti-human cytomegalovirus activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in vitro.

E. De Clercq, J. Neyts, J. Balzarini, 1991, Antiviral research.

New neplanocin analogues. 1. Synthesis of 6'-modified neplanocin A derivatives as broad-spectrum antiviral agents.

E. De Clercq, S. Shuto, M. Hosoya, 1992, Journal of medicinal chemistry.

Synthesis and antitumor and antiviral properties of 5-halo- and 5-(trifluoromethyl)-2'-deoxyuridine 3',5'-cyclic monophosphates and neutral triesters.

E. De Clercq, J. Balzarini, L. Otvös, 1986, Journal of medicinal chemistry.

Human immunodeficiency virus type 1 drug-resistance patterns with different 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives.

E. De Clercq, J. Balzarini, E. Clercq, 1993, Molecular pharmacology.

Metabolism of EICAR (5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide), a potent inhibitor of inosinate dehydrogenase.

E. De Clercq, A. Matsuda, J. Balzarini, 1998, Advances in experimental medicine and biology.