Yuko Mitobe

Effects of a Novel Y5 Antagonist in Obese Mice: Combination With Food Restriction or Sibutramine

D. Macneil, H. Iwaasa, H. Matsushita, 2008, Obesity.

Effects of a Novel Y5 Antagonist in Obese Mice: Combination With Food Restriction

D. Macneil, A. Kanatani, T. Fukami, 2008 .

A neuropeptide Y Y5 antagonist selectively ameliorates body weight gain and associated parameters in diet-induced obese mice.

D. Macneil, H. Iwaasa, L. V. D. van der Ploeg, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Comparison of independent and combined chronic anti-obese effects of NPY Y2 receptor agonist, PYY(3-36), and NPY Y5 receptor antagonist in diet-induced obese mice

H. Iwaasa, A. Kanatani, Y. Mitobe, 2009, Peptides.

Identification of positron emission tomography ligands for NPY Y5 receptors in the brain.

H. Iwaasa, T. Ohe, A. Kanatani, 2009, Bioorganic & medicinal chemistry letters.

Syntheses and structure-activity relationships of novel, potent, and selective trans-2-[3-oxospiro[isobenzofuran-1(3H),1'-cyclohexan]-4'-yl]benzimidazole NPY Y5 receptor antagonists.

H. Iwaasa, K. Matsuda, M. Ishikawa, 2008, Bioorganic & medicinal chemistry letters.

Synthesis, structure-activity relationships, and biological profiles of a quinazolinone class of histamine H3 receptor inverse agonists.

R. Yoshimoto, T. Fukami, Sayaka Ito, 2008, Journal of medicinal chemistry.

State of the Art: Development of a Sublingual Allergy Immunotherapy Tablet for Allergic Rhinitis in Japan.

Y. Mitobe, K. Lund, K. Ohashi-Doi, 2020, Biological & pharmaceutical bulletin.

Synthesis and evaluation of structurally constrained quinazolinone derivatives as potent and selective histamine H3 receptor inverse agonists.

Shigeru Tokita, Shiho Ishikawa, Akane Ishihara, 2008, Journal of medicinal chemistry.

Synthesis, structure-activity relationships, and biological profiles of a dihydrobenzoxathiin class of histamine H(3) receptor inverse agonists.

R. Yoshimoto, Y. Mitobe, Sayaka Ito, 2009, Bioorganic & medicinal chemistry letters.

Detailed pharmacological characterization of GT-2331 for the rat histamine H3 receptor.

D. Macneil, R. Yoshimoto, Takao Nakamura, 2006, European journal of pharmacology.