Ira Pastan

Isolation of a high-affinity stable single-chain Fv specific for mesothelin from DNA-immunized mice by phage display and construction of a recombinant immunotoxin with anti-tumor activity.

I. Pastan, P. Chowdhury, R. Beers, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Laboratory and clinical evaluation of conjugate vaccines composed of Staphylococcus aureus type 5 and type 8 capsular polysaccharides bound to Pseudomonas aeruginosa recombinant exoprotein A

I. Pastan, J. Shiloach, A. Fattom, 1993, Infection and immunity.

Recombinant immunotoxins specific for a mutant epidermal growth factor receptor: targeting with a single chain antibody variable domain isolated by phage display.

I. Pastan, R. Beers, C. Pegram, 1996, Proceedings of the National Academy of Sciences of the United States of America.

The N-terminal region of the 37-kDa translocated fragment of Pseudomonas exotoxin A aborts translocation by promoting its own export after microsomal membrane insertion.

I. Pastan, C. Theuer, J. Buchner, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Crystal structure of the catalytic domain of Pseudomonas exotoxin A complexed with a nicotinamide adenine dinucleotide analog: implications for the activation process and for ADP ribosylation.

I. Pastan, D. Davies, F. Dyda, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Primate antibody response to immunotoxin: serological and computer-aided analysis of epitopes on a truncated form of Pseudomonas exotoxin

I. Pastan, S. Jung, B. Lee, 1994, Infection and immunity.

Analysis of Pseudomonas exotoxin activation and conformational changes by using monoclonal antibodies as probes

I. Pastan, D. Fitzgerald, M. Ogata, 1991, Infection and immunity.