D. Hughes

发表

Synthesis, crystal structure and complexation behaviour study of an efficient Cu2+ ratiometric fluorescent chemosensor based on thiacalix[4]arene

C. Redshaw, P. Georghiou, Xi Zeng, 2015 .

Tri-substituted hexahomotrioxacalix[3]arene derivatives bearing imidazole units: synthesis and extraction properties for cations and chromate anions.

C. Redshaw, Xi Zeng, D. Hughes, 2013, Organic & biomolecular chemistry.

Synthesis and inclusion properties of C3-symmetric triazole derivatives based on hexahomotrioxacalix[3]arene

T. Kinoshita, C. Redshaw, Xi Zeng, 2012 .

Synthesis of a class of core-modified aza-BODIPY derivatives.

S. Coles, G. Tizzard, A. Cammidge, 2014, The Journal of organic chemistry.

Aryl trihydroxyborates: easily isolated discrete species convenient for direct application in coupling reactions.

A. J. Whitehead, A. Cammidge, H. Gopee, 2006, Organic letters.

Synthesis, lead lability and ring deformation of three 1,4,8,11,15,18,22,25-octasubstituted phthalocyaninato lead derivatives

A. Powell, I. Chambrier, M. Cook, 2006 .

X-Ray crystallographic studies of three substituted indium(III) phthalocyanines: effect of ring substitution and the axial ligand on molecular geometry and packing

I. Chambrier, M. Cook, Aurélien Auger, 2005 .

Applications of Flow Chemistry in Drug Development: Highlights of Recent Patent Literature

D. Hughes, D. Hughes, 2018 .

Solid state NMR and X-ray diffraction studies of alpha-D-galacturonic acid monohydrate.

P. Belton, D. Hughes, H. Tang, 2001, Carbohydrate research.

Peracetylated alpha-D-glucopyranosyl fluoride and peracetylated alpha-maltosyl fluoride.

R. Field, D. Hughes, S. Dedola, 2010, Acta crystallographica. Section C, Crystal structure communications.

Synthesis of an anti-methicillin-resistant Staphylococcus aureus (MRSA) carbapenem via stannatrane-mediated Stille coupling.

P. Reider, D. Hughes, Y. Hsiao, 2000, Organic letters.

Olefin Metathesis in Drug Discovery and Development—Examples from Recent Patent Literature

D. Hughes, Philip Wheeler, D. Ene, 2017 .

Unusual Nucleophilic Addition of Grignard Reagents in the Synthesis of 4-Amino-pyrimidines

G. Stephenson, D. Hughes, L. Ward, 2018, ACS omega.

Dimethyltitanocene: From Millimole to Kilomole

D. Cai, Brian K. Johnson, Linda D. Tuma, 2004 .

The anticancer and EGFR-TK/CDK-9 dual inhibitory potentials of new synthetic pyranopyrazole and pyrazolone derivatives: X-ray crystallography, in vitro, and in silico mechanistic investigations.

M. Abdelgawad, A. Musa, Sami I. Alzarea, 2023, Journal of biomolecular structure & dynamics.

Diastereoselective Self-Assembly and Crystal Structure of the Chiral, Anionic Molybdenum-Based [2+2] Molecular Square [{MoO2(C21H20O4)}2]4-

D. Hughes, A. Davies, †. Anne-K. Duhme, 1998 .

(C^Npz^C)AuIII complexes of acyclic carbene ligands: synthesis and anticancer properties.

M. O'Connell, M. Bochmann, M. Searcey, 2017, Dalton transactions.

Formation of Gold(III) Alkyls from Gold Alkoxide Complexes

I. Chambrier, P. Budzelaar, M. Bochmann, 2017, Organometallics.

Ligand transfer reactions of mixed-metal lanthanide/magnesium allyl complexes with β-diketimines: Synthesis, structures, and ring-opening polymerization catalysis

L. Sánchez-Barba, S. M. Humphrey, M. Bochmann, 2006 .

Mechanistic Studies of the Suzuki Cross-Coupling Reaction

D. Hughes, T. Verhoeven, A. King, 1994 .

Cyclometallated Au(iii) dithiocarbamate complexes: synthesis, anticancer evaluation and mechanistic studies.

Zoë A. E. Waller, M. O'Connell, M. Bochmann, 2018, Metallomics : integrated biometal science.

Patent Review of Manufacturing Routes to Recently Approved Oncology Drugs: Ibrutinib, Cobimetinib, and Alectinib

D. Hughes, 2016 .

PROGRESS IN THE FISCHER INDOLE REACTION. A REVIEW

D. Hughes, D. Hughes, 1993 .

Synthesis and structures of complexes with axially chiral isoquinolinyl-naphtholate ligands.

Joseph A. Wright, Joseph A Wright, C. Alonso-Moreno, 2009, Dalton transactions.

6-azapyrimidine-2'-deoxy-4'-thionucleosides: antiviral agents against TK+ and TK- HSV and VZV strains.

E. De Clercq, J. Balzarini, C. Simons, 2004, Journal of medicinal chemistry.

Synthesis and structures of diphosphinoamide complexes of nickel, palladium and platinum

M. Bochmann, D. Hughes, M. Said, 2006 .

The search for a coordinated dialkyl disulphide: The crystal and molecular structure of (μ-ethanedithiolato)bis(tricarbonyliron)(FeFe)

D. R. Paulson, D. Hughes, G. Leigh, 1986 .

Synthesis and structures of new binuclear zinc alkyl, aryl and aryloxo complexes

Duncan A. J. Harding, Joseph A. Wright, Timothy J. Woodman, 2008 .

Titanium, zinc and alkaline-earth metal complexes supported by bulky O,N,N,O-multidentate ligands: syntheses, characterisation and activity in cyclic ester polymerisation.

S. M. Humphrey, M. Bochmann, D. Hughes, 2006, Dalton transactions.

Thallium(I) sandwich, multidecker, and ether complexes stabilized by weakly-coordinating anions: a spectroscopic, structural, and theoretical investigation.

Joseph A. Wright, M. Bochmann, D. Hughes, 2007, Journal of the American Chemical Society.

9.1 Introduction to Industrial Applications of Asymmetric Synthesis

D. Hughes, D. Hughes, 2012 .

Efficient and general protocol for the copper-free sonogashira coupling of aryl bromides at room temperature.

D. Hughes, P. Dormer, J. Murry, 2003, Organic letters.

Synthesis of alpha- and beta-D-glucopyranosyl triazoles by CuAAC 'click chemistry': reactant tolerance, reaction rate, product structure and glucosidase inhibitory properties.

M. Rejžek, R. Field, S. Nepogodiev, 2010, Carbohydrate research.

Preparation of crystallinep-nitrobenzyl 2-hydroxymethyl carbapenem as a key intermediate for the anti-MRS carbapenem L-786,392

D. Hughes, N. Yasuda, Chun-hua Yang, 1999 .

Methyl Ester Functionalized Phenalenyl Arene- and Bipyridine-Ruthenium-Based Complexes for Electroactive Langmuir-Blodgett Films.

H. Winnischofer, R. Ribeiro, Eduard Westphal, 2019, Inorganic chemistry.

Crystallographic study of the binding of a trifluoroacetyl dipeptide anilide inhibitor with elastase.

L. Sieker, J. Bieth, D. Hughes, 1982, Journal of molecular biology.

RuX = C (X F or H) interactions in complex compounds. Preparation and crystal structures of [) (SC6F5)2(PMe2Ph)2] and [-2)(C6H5)22]

A. Hills, D. Hughes, H. Torrens, 1989 .

A novel route to methyleneamido ligands by protonation of nitriles ligating an electron-rich centre. Synthesis of trans-[ReCl(NCR)(dppe)2](R = alkyl or aryl, dppe = Ph2PCH2CH2PPh2) and [ReCl(NCHC6H4OMe-4)(dppe)2][BF4]

A. Pombeiro, R. L. Richards, D. Hughes, 1988 .

Biocatalysis in Drug Development—Highlights of the Recent Patent Literature

D. Hughes, D. Hughes, 2018, Organic Process Research & Development.

Quest for a Cure: Potential Small-Molecule Treatments for COVID-19, Part 2

D. Hughes, D. Hughes, 2021, Organic process research & development.

Synthesis and structural characterization of a flexible tetradentate ligand and its copper(I) coordination polymers

D. Hughes, E. Ahmadi, K. Marjani, 2011 .

Quest for a COVID-19 Cure by Repurposing Small-Molecule Drugs: Mechanism of Action, Clinical Development, Synthesis at Scale, and Outlook for Supply

D. Hughes, L. Kvaernø, C. De savi, 2020, Organic process research & development.

Controlling carbon monoxide binding at di-iron units related to the iron-only hydrogenase sub-site.

Xiaoming Liu, C. Pickett, Q. Luo, 2008, Chemical communications.

A novel {FeI-FeII-FeII-FeI} iron thiolate carbonyl assembly which electrocatalyses hydrogen evolution.

Xiaoming Liu, C. Pickett, D. Hughes, 2005, Chemical communications.

{2Fe3S} clusters related to the di-iron sub-site of the H-centre of all-iron hydrogenases

C. Pickett, D. Hughes, S. C. Davies, 2001 .

A di-iron dithiolate possessing structural elements of the carbonyl/cyanide sub-site of the H-centre of Fe-only hydrogenase

C. Pickett, D. Hughes, David J Evans, 1999 .

The Mitsunobu Reaction

D. Hughes, D. Hughes, 2004 .

Discotic triphenylene twins linked through thiophene bridges: controlling nematic behavior in an intriguing class of functional organic materials.

A. Cammidge, D. Hughes, Liang Zhang, 2012, The Journal of organic chemistry.

Antiaromatic twinned triphenylene discotics showing nematic phases and 2-dimensional pi-overlap in the solid state.

A. Cammidge, H. Gopee, D. Hughes, 2010, Chemical communications.

Probing the structural factors influencing columnar mesophase formation and stability in triphenylene discotics.

A. Cammidge, Juanjuan Li, Céline Chausson, 2009, Chemical communications.

Lattice effects in the Mössbauer spectra of salts of [Fe4S4{S(CH2)nOH}4]2−. Crystal structures of [PPh4]2[Fe4S4{S(CH2)nOH}4] (n=2, 3 and 4)

J. E. Barclay, D. Hughes, David J Evans, 1999 .

A Combined “Electrochemical–Frustrated Lewis Pair” Approach to Hydrogen Activation: Surface Catalytic Effects at Platinum Electrodes

Gregory Wildgoose, Robin Blagg, D. Hughes, 2014, Chemistry.

An Electrochemical Study of Frustrated Lewis Pairs: A Metal-Free Route to Hydrogen Oxidation

V. Oganesyan, Gregory Wildgoose, D. Hughes, 2014, Journal of the American Chemical Society.

Intra- and intermolecular N-H...F-C hydrogen-bonding interactions in amine adducts of tris(pentafluorophenyl)borane and -alane.

S. Coles, M. Hursthouse, M. Light, 2005, Inorganic chemistry.

Zinc(II) η1- and η2-Toluene Complexes: Structure and Bonding in Zn(C6F5)2·(toluene) and Zn(C6F4-2-C6F5)2·(toluene)

M. Bochmann, E. Martín, D. Hughes, 2006 .

Zwitterionic Mixed-Carbene Coinage Metal Complexes: Synthesis, Structures, and Photophysical Studies

M. Bochmann, Mikko Linnolahti, D. Hughes, 2019, European Journal of Inorganic Chemistry.

Synthesis and Structure of the Dimethyl Sulfide Adducts of Mono- and Bis(pentafluorophenyl)borane

S. Lancaster, D. Hughes, Anna-Marie Fuller, 2010 .

Determination of structural features of electrogenerated trans-[MoCl(NMe)(Ph2PCH2CH2PPh2)2]2+ by multinuclear electron paramagnetic resonance and electron nuclear double resonance spectroscopy and comparison of interatomic distances with those measured by X-ray analysis of the parent monocation

D. Lowe, C. Pickett, Modher Y. Mohammed, 1990 .

Copper complexes of 1,3-bis(2-pyridyl)-1-thiapropane (bpt) andpyridine-2(1H)-thione. Crystal structure of[{Cu(µ-O2CMe)2(bpt)}2] and metal-promoted cleavage of bpt

D. Hughes, M. Durrant, R. L. Richards, 1997 .

Hammett and Broensted-type relationships in reactions of 9-substituted fluorenyl anions with benzyl halides

F. Bordwell, D. Hughes, D. Hughes, 1980 .

Open-resorcinarenes, a new family of multivalent scaffolds.

S. E. Matthews, D. Hughes, M. Cominetti, 2016, Organic & biomolecular chemistry.

Highlights of the Recent U.S. Patent Literature: Focus on Metathesis

D. Hughes, D. Hughes, 2016 .

An Oxalate-Bridged Copper(II) Complex Combining Monodentate Benzoate, 2,2′-bipyridine and Aqua Ligands: Synthesis, Crystal Structure and Investigation of Magnetic Properties

M. Briganti, F. S. Santana, R. Ribeiro, 2020, Molecules.

Combining two-directional synthesis and tandem reactions: desymmetrisation by intramolecular cycloaddition/triazoline fragmentation.

M. Rejžek, J. V. van Maarseveen, R. Stockman, 2005, Chemical communications.

A two-directional synthesis of (+/-)-perhydrohistrionicotoxin.

A. Sinclair, R. Stockman, P. Szeto, 2004, The Journal of organic chemistry.

Synthesis, structural properties, electrophilic substitution reactions and DFT computational studies of calix[3]benzofurans

C. Redshaw, P. Georghiou, Taisuke Matsumoto, 2016 .

Allene-derived gold and platinum complexes: synthesis and first applications in catalysis.

M. Muñoz, D. Hughes, H. Maliszewska, 2020, Dalton transactions.

Conclusive evidence for a retention-retention pathway for the molybdenum-catalyzed asymmetric alkylation.

K. Jack, V. Bonnet, Yong-kui Sun, 2004, Journal of the American Chemical Society.

PROGRESS IN THE MITSUNOBU REACTION. A REVIEW

D. Hughes, D. Hughes, 1996 .

Combining two-directional synthesis and tandem reactions: an efficient strategy for the total syntheses of (+/-)-hippodamine and (+/-)-epi-hippodamine.

M. Rejžek, R. Stockman, D. Hughes, 2005, Organic & biomolecular chemistry.

Naphthoquinones of Sinningia reitzii and Anti-inflammatory/Antinociceptive Activities of 8-Hydroxydehydrodunnione.

D. Hughes, M. Stefanello, A. Zampronio, 2017, Journal of natural products.

Reactivity of “Ligand-Free” Au+: C–H and C–C Activation versus π Coordination

N. Savjani, M. Bochmann, S. Lancaster, 2012 .

The synthesis, structure and ethene polymerisation catalysis of mono(salicylaldiminato) titanium and zirconium complexes.

S. Coles, M. Hursthouse, M. Light, 2005, Dalton transactions.

Vanadium complexes possessing N2O2S2-based ligands: highly active procatalysts for the homopolymerization of ethylene and copolymerization of ethylene/1-hexene.

C. Redshaw, D. Hughes, Damien M. Homden, 2007, Inorganic chemistry.

Vanadium(III) phenoxyimine complexes for ethylene or ε-caprolactone polymerization: mononuclear versus binuclear pre-catalysts

Y. Chao, A. Walton, C. Redshaw, 2013 .

Synthesis of neutral and zwitterionic phosphinomethylpyrrolato complexes of nickel

Joseph A. Wright, Joseph A Wright, M. Bochmann, 2009 .

Ligand Mobility and Solution Structures of the Metallocenium Ion Pairs [Me2C(Cp)(fluorenyl)MCH2SiMe3+···X−] (M = Zr, Hf; X = MeB(C6F5)3, B(C6F5)4)

Joseph A. Wright, Joseph A Wright, L. Cavallo, 2008 .

The synthesis of new weakly coordinating diborate anions: anion stability as a function of linker structure and steric bulk.

Joseph A. Wright, Joseph A Wright, P. Horton, 2006, Dalton transactions.

Tri- and tetra-dentate imine vanadyl complexes: synthesis, structure and ethylene polymerization/ring opening polymerization capability.

Joseph A. Wright, Joseph A Wright, C. Redshaw, 2014, Dalton transactions.

Complexes of tertiary phosphines with iron(II) and dinitrogen, dihydrogen, and other small molecules

A. Hills, D. Hughes, G. Leigh, 1990 .

Reactions of bis[1,2-bis(dialkylphosphino)ethane]-(dihydrogen)hydridoiron(1+) with alkynes

D. Hughes, A. T. Rowley, M. Jiménez-Tenorio, 1993 .

Bis[1,2-bis(dimethylphosphino)ethane]dihydrogenhydridoiron(II) tetraphenylborate as a model for the function of nitrogenases

A. Hills, D. Hughes, A. T. Rowley, 1993 .

Isolation and characterisation of iron(II) complexes with dinitrogen, and of other derivatives, especially from phenylacetylene

D. Hughes, A. T. Rowley, M. Jiménez-Tenorio, 1993 .

The reactions of [FeH(H2)(Me2PCH2CH2PMe2)2][BPh4] with allenes and acetylenes, and the reduction of cyclopropane by molybdenum nitrogenases

A. Hills, C. McKenna, D. Hughes, 1991 .

Crystallization-Induced Asymmetric Transformation: Stereospecific Synthesis of a Potent Peripheral CCK Antagonist

P. Reider, E. Grabowski, D. Hughes, 1987 .

Unexpected phenol production from arylboronic acids under palladium-free conditions; organocatalyzed air oxidation.

A. Cammidge, Daniel González-Lucas, H. Gopee, 2011, Organic letters.

InP nanowires from surfactant-free thermolysis of single molecule precursors.

T. Nann, Chiranjib Banerjee, M. Bochmann, 2012, Dalton transactions.

Novel ion-pair receptors based on hexahomotrioxacalix[3]arene derivatives.

C. Redshaw, Xi Zeng, D. Hughes, 2011, Organic & biomolecular chemistry.

First small molecular inhibitors of T. brucei dolicholphosphate mannose synthase (DPMS), a validated drug target in African sleeping sickness.

Terry K. Smith, H. Denton, Benjamin Young, 2009, Bioorganic & Medicinal Chemistry Letters.

An oxalate-bridged oxidovanadium(IV) binuclear complex that improves the in vitro cell uptake of a fluorescent glucose analog

G. G. Nunes, J. Soares, F. Rego, 2021, Polyhedron.

Mechanistic Study of the Jacobsen Asymmetric Epoxidation of Indene.

C. Senanayake, P. Reider, D. Hughes, 1997, The Journal of organic chemistry.

Gold peroxide complexes and the conversion of hydroperoxides into gold hydrides by successive oxygen-transfer reactions

Joseph A. Wright, David L. Hughes, Joseph A Wright, 2013, Nature Communications.

Stereoselective synthesis of N-alkylaziridines from N-chloroamines.

V. Savić, D. Hughes, S. Bew, 2006, Chemical Communications.

Induction of Planar Chirality Using Asymmetric Click Chemistry by a Novel Desymmetrisation of 1,3-Bisalkynyl Ferrocenes

G. Stephenson, D. Hughes, A. J. Wright, 2019, European Journal of Organic Chemistry.

Application of the Suzuki reaction to the asymmetric desymmetrisation of 1,2-and 1,3-disubstituted bulky cobalt metallocenes

C. Richards, D. Hughes, E. Bergin, 2010 .

Synthesis, Structure, and Luminescent Behavior of Anionic Oligomeric and Polymeric Ag2Au2 Clusters

N. Savjani, M. Bochmann, D. Hughes, 2012 .

An efficient synthesis of an alphavbeta3 antagonist.

L. Tan, M. Palucki, R. Volante, 2004, The Journal of organic chemistry.

Review of Synthetic Routes and Crystalline Forms of the Oncology Drugs Capmatinib, Selpercatinib, and Pralsetinib

D. Hughes, 2021, Organic Process Research & Development.

Structure and magnetic properties of two new lanthanide complexes with the 1-((E)-2-pyridinylmethylidene)semicarbazone ligand

R. Ribeiro, D. Hughes, F. S. Nunes, 2019, Journal of Molecular Structure.

Improved synthesis of quinaldines by the skraup reaction

M. Mertzman, D. Hughes, Z. Song, 1993 .

Patent Review of Manufacturing Routes to Recently Approved PARP Inhibitors: Olaparib, Rucaparib, and Niraparib

D. Hughes, D. Hughes, 2017 .

Two new pseudohalide-bridged Cu(II) complexes with a hydrazone ligand: Syntheses, crystal structures and magnetic studies

S. Mitra, Soma Sen, Sambuddha Banerjee, 2008 .

Synthesis, crystal structures and magnetic studies of dicyanamide bridged two new 1D copper(II) complexes

S. Mitra, Soma Sen, G. Rosair, 2007 .

Two new end-to-end single dicyanamide bridged Cu(II) complexes with Schiff base ligands: Structural, electrochemical and magnetic properties

S. Mitra, J. Sutter, G. Yap, 2006 .

Synthesis, single crystal X-ray structure and W-band (95 GHz) EPR spectroscopy of a new anionic isoindoline aminoxyl: synthesis and characterisation of some derivatives

S. Bottle, A. Smirnov, D. Hughes, 2000 .

Organocatalytic aziridine synthesis using F+ salts.

J. Liddle, S. Fairhurst, D. Hughes, 2009, Organic letters.

Expedient synthesis of substituted (S)-N-(α-methylbenzyl)aziridines

V. Savić, D. Hughes, S. Bew, 2006 .

Structure of dimethyl(phenyl)phosphonium tris(1,2-benzenedithiolato)tungsten(V)

A. Hills, R. Morris, D. Hughes, 1993 .

Pyridine and benzonitrile adducts of bis(4-nonafluorobiphenyl)zinc

L. Male, M. Hursthouse, S. Lancaster, 2010 .

The Remarkable Solvent-Dependent Crystallization of the Mono- and Bis(4-pyrrol-1-ylbenzonitrile) Adducts of Bis(pentafluorophenyl)zinc

S. Lancaster, E. Martín, D. Hughes, 2006 .

Four new dinuclear Cu(ii) hydrazone complexes using various organic spacers: syntheses, crystal structures, DNA binding and cleavage studies and selective cell inhibitory effect towards leukemic and normal lymphocytes.

Saurabh Das, S. Mitra, Soma Sen, 2009, Dalton transactions.

Pseudohalide-induced structural variations in hydrazone-based metal complexes: Syntheses, electrochemical studies and structural aspects

R. Butcher, S. Batten, S. Mitra, 2008 .