Kaori Takakusagi

Use of phage display technology for the determination of the targets for small-molecule therapeutics

K. Sakaguchi, F. Sugawara, Y. Takakusagi, 2010, Expert opinion on drug discovery.

A Multimodal Molecular Imaging Study Evaluates Pharmacological Alteration of the Tumor Microenvironment to Improve Radiation Response.

James B. Mitchell, K. Sakaguchi, S. Naz, 2018, Cancer research.

Binding region and interaction properties of sulfoquinovosylacylglycerol (SQAG) with human vascular endothelial growth factor 165 revealed by biosensor-based assays

K. Sakaguchi, F. Sugawara, Yuki Matsumoto, 2011 .

Screening of a library of T7 phage-displayed peptides identifies alphaC helix in 14-3-3 protein as a CBP501-binding site.

K. Sakaguchi, F. Sugawara, Yuki Matsumoto, 2011, Bioorganic & medicinal chemistry.

Phage display technology for target determination of small-molecule therapeutics: an update

K. Sakaguchi, F. Sugawara, Y. Takakusagi, 2020, Expert opinion on drug discovery.

Camptothecin (CPT) directly binds to human heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) and inhibits the hnRNP A1/topoisomerase I interaction.

Kazunori Takada, Yoichi Takakusagi, Yoshihiro Kanai, 2011, Bioorganic & medicinal chemistry.

Identification of C10 biotinylated camptothecin (CPT-10-B) binding peptides using T7 phage display screen on a QCM device.

K. Sakaguchi, F. Sugawara, Y. Takakusagi, 2007, Bioorganic & medicinal chemistry.

A sulfoglycolipid beta-sulfoquinovosyldiacylglycerol (betaSQDG) binds to Met1-Arg95 region of murine DNA polymerase lambda (Mmpol lambda) and inhibits its nuclear transit.

K. Sakaguchi, F. Sugawara, Y. Takakusagi, 2010, Protein engineering, design & selection : PEDS.

Cyclosporin A Associated Helicase-Like Protein Facilitates the Association of Hepatitis C Virus RNA Polymerase with Its Cellular Cyclophilin B

K. Morohashi, K. Sakaguchi, F. Sugawara, 2011, PloS one.