Lotta J Happonen

发表

Distinct Serotypes of Streptococcal M Proteins Mediate Fibrinogen-Dependent Platelet Activation and Proinflammatory Effects

J. Malmström, Sounak Chowdhury, L. Happonen, 2021, Infection and immunity.

The structure of human dermatan sulfate epimerase 1 emphasizes the importance of C5-epimerization of glucuronic acid in higher organisms† †Electronic supplementary information (ESI) available. See DOI: 10.1039/d0sc05971d

Lars Malmström, Hamed Khakzad, J. Malmström, 2020, Chemical science.

Molecular view of ER membrane remodeling by the Sec61/TRAP translocon

J. Huiskonen, L. Happonen, M. Javanainen, 2022, bioRxiv.

Interaction with the host: the role of fibronectin and extracellular matrix proteins in the adhesion of Gram-negative bacteria

J. Malmström, M. Schütz, L. Happonen, 2019, Medical Microbiology and Immunology.

A quantitative Streptococcus pyogenes–human protein–protein interaction map reveals localization of opsonizing antibodies

Lars Malmström, L. Björck, Hamed Khakzad, 2019, Nature Communications.

Targeted Proteomics and Absolute Protein Quantification for the Construction of a Stoichiometric Host-Pathogen Surface Density Model*

Lars Malmström, Johan Teleman, Johan Malmström, 2017, Molecular & Cellular Proteomics.

BtuB-Dependent Infection of the T5-like Yersinia Phage ϕR2-01

M. Skurnik, L. Happonen, J. Jun, 2021, Viruses.

The Structure of the NTPase That Powers DNA Packaging into Sulfolobus Turreted Icosahedral Virus 2

A. Goldman, T. Kajander, S. Butcher, 2013, Journal of Virology.

Development of Phage-Based Antibody Fragment Reagents for Affinity Enrichment of Bacterial Immunoglobulin G Binding Proteins.

J. Malmström, H. Persson, L. Happonen, 2015, Journal of proteome research.

Multienzyme deep learning models improve peptide de novo sequencing by mass spectrometry proteomics

Hamed Khakzad, J. Malmström, L. Happonen, 2022, bioRxiv.

Reduced binding of apoE4 to complement factor H promotes amyloid‐β oligomerization and neuroinflammation

V. Leinonen, M. Varjosalo, P. Saavalainen, 2023, EMBO reports.

IdeS, a secreted proteinase of Streptococcus pyogenes, is bound to a nuclease at the bacterial surface where it inactivates opsonizing IgG antibodies

I. Frick, Sebastian Wrighton, Pontus Nordenfelt, 2023, Journal of Biological Chemistry.

Immunomodulating Enzymes from Streptococcus pyogenes—In Pathogenesis, as Biotechnological Tools, and as Biological Drugs

M. Collin, Lotta J Happonen, 2024, Microorganisms.

Development of phage-based antibody fragment reagents for affinity enrichment of bacterial IgG binding proteins

J. Malmström, S. Waldemarson, C. Karlsson, 2018 .

Host-Pathogen Adhesion as the Basis of Innovative Diagnostics for Emerging Pathogens

S. Peyman, A. Goldman, M. Nilges, 2021, Diagnostics.

5th CryoNET Symposium

D. Logan, Filippo Vascon, L. Cendron, 2022 .

Functional and Structural Properties of a Novel Protein and Virulence Factor (Protein sHIP) in Streptococcus pyogenes *

L. Björck, M. Varjosalo, George A. Rosenberger, 2014, The Journal of Biological Chemistry.

Bacteriophage Mu integration in yeast and mammalian genomes

F. Bushman, C. Berry, Nirav Malani, 2008, Nucleic acids research.

Snapshots of actin and tubulin folding inside the TRiC chaperonin

E. Pardon, J. Steyaert, W. Yue, 2021, Nature Structural & Molecular Biology.

Structural proteomics, electron cryo-microscopy and structural modeling approaches in bacteria–human protein interactions

Hamed Khakzad, J. Malmström, Sounak Chowdhury, 2020, Medical Microbiology and Immunology.

Familial Relationships in Hyperthermo- and Acidophilic Archaeal Viruses

S. Butcher, Xu Peng, P. Redder, 2010, Journal of Virology.

Streptococcal protein SIC activates monocytes and induces inflammation

L. Björck, I. Frick, L. Happonen, 2021, iScience.

The hinge-engineered IgG1-IgG3 hybrid subclass IgGh47 potently enhances Fc-mediated function of anti-streptococcal and SARS-CoV-2 antibodies.

Yasaman Karami, Hamed Khakzad, J. Malmström, 2024, Nature communications.

A human monoclonal antibody bivalently binding two different epitopes in streptococcal M protein mediates immune function

L. Björck, Hamed Khakzad, J. Malmström, 2022, EMBO molecular medicine.

Rapid determination of quaternary protein structures in complex biological samples

Lars Malmström, Johan Teleman, Johan Malmström, 2019, Nature Communications.