Philippe Beaune

发表

Human cytochromes P450 expressed in Escherichia coli: production of specific antibodies.

P. Beaune, I. de Waziers, J. Gautier, 1996, Toxicology.

Identification of the cytochrome P450 IIIA family as the enzymes involved in the N-demethylation of tamoxifen in human liver microsomes.

P. Beaune, F. Berthou, C. Riché, 1991, Biochemical pharmacology.

Involvement of cytochrome P450 3A4 enzyme in the N-demethylation of methadone in human liver microsomes.

P. Beaune, F. Berthou, J. Bail, 1996, Chemical research in toxicology.

In vitro metabolism of quinidine: the (3S)-3-hydroxylation of quinidine is a specific marker reaction for cytochrome P-4503A4 activity in human liver microsomes.

P. Beaune, K. Brøsen, J. Flinois, 1999, The Journal of pharmacology and experimental therapeutics.

Specificity of in vitro covalent binding of tienilic acid metabolites to human liver microsomes in relationship to the type of hepatotoxicity: comparison with two directly hepatotoxic drugs.

P. Beaune, D. Mansuy, P. Dansette, 1994, Chemical research in toxicology.

Human cytochrome P450 2E1 (CYP2E1): from genotype to phenotype.

P. Beaune, I. de Waziers, F. Berthou, 1996, Pharmacogenetics.

Both cytochromes P450 2E1 and 1A1 are involved in the metabolism of chlorzoxazone.

A. Guillouzo, F. Morel, F. Berthou, 1993, Chemical research in toxicology.

Principal xenobiotic-metabolizing enzyme systems in human head and neck squamous cell carcinoma.

P. Beaune, I. de Waziers, F. Janot, 1993, Carcinogenesis.

Involvement of cytochrome P450 3A enzyme family in the major metabolic pathways of toremifene in human liver microsomes.

P. Beaune, L. Kangas, F. Berthou, 1994, Biochemical pharmacology.

Metabolic activation of the nitroaromatic antiandrogen flutamide by rat and human cytochromes P-450, including forms belonging to the 3A and 1A subfamilies.

P. Beaune, C. Wolf, A. Berson, 1993, The Journal of pharmacology and experimental therapeutics.

The use of human in vitro metabolic parameters to explore the risk assessment of hazardous compounds: the case of ethylene dibromide.

P. Beaune, N. Vermeulen, P. van Bladeren, 1997, Toxicology and applied pharmacology.

Inhibition by omeprazole of proguanil metabolism: mechanism of the interaction in vitro and prediction of in vivo results from the in vitro experiments.

C. Funck-Brentano, L. Becquemont, P. Jaillon, 1997, The Journal of pharmacology and experimental therapeutics.

Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1

P. Beaune, F. Guengerich, Chung S. Yang, 1990 .