Donald R. Buhler

发表

Rainbow trout cytochrome P450s: purification, molecular aspects, metabolic activity, induction and role in environmental monitoring.

D. Buhler, J. Wang-Buhler, J. Wang‐Buhler, 1998, Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology.

Xenobiotics and xenoestrogens in fish: modulation of cytochrome P450 and carcinogenesis.

D. Williams, D. Buhler, J. Lech, 1998, Mutation research.

Antioxidant and prooxidant actions of prenylated and nonprenylated chalcones and flavanones in vitro.

J. F. Stevens, C. Miranda, D. Buhler, 2000, Journal of agricultural and food chemistry.

Localization of cytochrome P-450 in the head and trunk kidney of rainbow trout (Salmo gairdneri).

D. Buhler, R. Lorenzana, O. Hedstrom, 1988, Toxicology and applied pharmacology.

Benzo[a]pyrene-hydroxylase catalyzed by purified isozymes of cytochrome P-450 from beta-naphthoflavone-fed rainbow trout.

D. Williams, D. Buhler, Donald R. Buhler, 1984, Biochemical pharmacology.

Comparison of rainbow trout and mammalian cytochrome P450 enzymes: evidence for structural similarity between trout P450 LMC5 and human P450IIIA4.

C. Miranda, D. Buhler, F. Guengerich, 1991, Biochemical and biophysical research communications.

Influence of prenylated and non-prenylated flavonoids on liver microsomal lipid peroxidation and oxidative injury in rat hepatocytes.

J. F. Stevens, C. Miranda, D. Buhler, 2001, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Comparison of hepatic in vitro metabolism of the pyrrolizidine alkaloid senecionine in sheep and cattle.

D. Buhler, A. Craig, J. Duringer, 2004, American journal of veterinary research.

Immunohistochemical localization and differential expression of cytochrome P450 3A27 in the gastrointestinal tract of rainbow trout.

D. Buhler, I. Cok, A. Şen, 2001, Toxicology and applied pharmacology.

Role of metabolism in monocrotaline-induced immunotoxicity in C57BL/6 mice.

N. Kerkvliet, D. Buhler, J. Deyo, 1994, Toxicology.

Protective role of dietary butylated hydroxyanisole against chemical-induced acute liver damage in mice.

J. A. Schmitz, C. Miranda, D. Buhler, 1983, Toxicology and applied pharmacology.

Consumption of poisonous plants (Senecio jacobaea, Symphytum officinale, Pteridium aquilinum, Hypericum perforatum) by rats: chronic toxicity, mineral metabolism, and hepatic drug-metabolizing enzymes.

C. Miranda, D. Buhler, P. Cheeke, 1982, Toxicology letters.

Method for determination of pyrrolizidine alkaloids and their metabolites by high-performance liquid chromatography.

D. Buhler, B. Kedzierski, Bogdan Kedzierski, 1986, Analytical biochemistry.

Determination of multiple forms of cytochrome P-450 in microsomes from the digestive gland of Cryptochiton stelleri.

Donald R. Buhler, D. Schlenk, 1989, Biochemical and biophysical research communications.

Purification and characterization of hepatic steroid hydroxylases from untreated rainbow trout.

C. Miranda, D. Buhler, M. Henderson, 1989, Archives of biochemistry and biophysics.

Comparative properties of purified cytochrome P-448 from beta-naphthoflavone treated rats and rainbow trout.

D. Williams, D. Buhler, Donald R. Buhler, 1983, Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.

Hepatic cytochrome P-450 isozymes and aryl hydrocarbon hydroxylase in English sole (Parophrys vetulus).

T. Collier, D. Buhler, U. Varanasi, 1986, Biochemical pharmacology.

Comparative in vitro metabolism of benzo[a]pyrene by recombinant zebrafish CYP1A and liver microsomes from beta-naphthoflavone-treated rainbow trout.

C. Miranda, D. Buhler, W. Baird, 2006, Aquatic toxicology.

Heterologous expression of CYP2K1 and identification of the expressed protein (BV-CYP2K1) as lauric acid (omega-1)-hydroxylase and aflatoxin B1 exo-epoxidase.

C. Miranda, D. Buhler, M. Henderson, 2000, Drug metabolism and disposition: the biological fate of chemicals.

Evaluation of chemicals as inhibitors of trout cytochrome P450s.

C. Miranda, D. Buhler, M. Henderson, 1998, Toxicology and applied pharmacology.

Immunological and biochemical characterization of cytochromes P-450 in mullet (Mugil cephalus): comparison with rainbow trout P-450s.

C. Miranda, D. Buhler, M. Henderson, 1994, Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology.

Induction of zebrafish (Brachydanio rerio) P450 in vivo and in cell culture.

C. Miranda, D. Buhler, P. Collodi, 1994, Xenobiotica; the fate of foreign compounds in biological systems.

A comparison of the effects of hexachlorobenzene, beta-naphthoflavone, and phenobarbital on cytochrome P-450 and mixed-function oxidases in Japanese quail.

D. Williams, D. Buhler, H. Carpenter, 1985, Journal of toxicology and environmental health.

Channel catfish liver monooxygenases. Immunological characterization of constitutive cytochromes P450 and the absence of active flavin-containing monooxygenases.

C. Miranda, D. Buhler, M. Ronis, 1993, Biochemical pharmacology.

Phytochemical-induced changes in gene expression of carcinogen-metabolizing enzymes in cultured human primary hepatocytes

S. Safe, S. Strom, P. Stapleton, 2004, Xenobiotica; the fate of foreign compounds in biological systems.

The effect of spironolactone treatment on the cytochrome P450-mediated metabolism of the pyrrolizidine alkaloid senecionine by hepatic microsomes from rats and guinea pigs.

D. Buhler, W. Chung, Donald R. Buhler, 1994, Toxicology and applied pharmacology.

Bioactivation and detoxication of the pyrrolizidine alkaloid senecionine by cytochrome P-450 enzymes in rat liver.

D. Williams, D. Buhler, F. Guengerich, 1989, Drug metabolism and disposition: the biological fate of chemicals.

Species differences in the hepatic microsomal enzyme metabolism of the pyrrolizidine alkaloids.

C. Miranda, D. Buhler, P. Cheeke, 1998, Toxicology letters.

The roles of CYP3A and CYP2B isoforms in hepatic bioactivation and detoxification of the pyrrolizidine alkaloid senecionine in sheep and hamsters.

C. Miranda, D. Buhler, P. Cheeke, 1998, Toxicology and applied pharmacology.