Belén Gómez-González

发表

The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability.

Rosa Luna, Andrés Aguilera, R. Luna, 2008, Molecular biology of the cell.

DNA Repair in Mammalian Cells

A. Aguilera, B. Pardo, B. Gómez‐González, 2009, Cellular and Molecular Life Sciences.

Controlling DNA replication origins in response to DNA damage – inhibit globally, activate locally

J. Diffley, M. Yekezare, B. Gómez-González, 2013, Journal of Cell Science.

Genome instability: a mechanistic view of its causes and consequences

A. Aguilera, Belén Gómez-González, 2008, Nature Reviews Genetics.

Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways

Cynthia J. Sakofsky, J. Haber, D. Gordenin, 2019, Microbial cell.

Genome Instability and Transcription Elongation Impairment in Human Cells Depleted of THO/TREX

Rosa Luna, Andrés Aguilera, R. Luna, 2011, PLoS genetics.

Transcription-mediated replication hindrance: a major driver of genome instability

A. Aguilera, B. Gómez‐González, Belén Gómez‐González, 2019, Genes & development.

Genome‐wide function of THO/TREX in active genes prevents R‐loop‐dependent replication obstacles

Katsuhiko Shirahige, Andrés Aguilera, Rodrigo Bermejo, 2011, The EMBO journal.

The Replication Checkpoint Protects Fork Stability by Releasing Transcribed Genes from Nuclear Pores

Andrea Cocito, Katsuhiko Shirahige, Andrés Aguilera, 2011, Cell.

AID Induces Double-Strand Breaks at Immunoglobulin Switch Regions and c-MYC Causing Chromosomal Translocations in Yeast THO Mutants

A. Aguilera, B. Gómez‐González, J. Ruiz, 2011, PLoS genetics.

Yeast Sen1 Helicase Protects the Genome from Transcription-Associated Instability

L. Steinmetz, Wu Wei, N. Proudfoot, 2011, Molecular cell.

Activation-induced cytidine deaminase action is strongly stimulated by mutations of the THO complex

A. Aguilera, B. Gómez‐González, Belén Gómez‐González, 2007, Proceedings of the National Academy of Sciences.

Genetic and molecular analysis of mitotic recombination in Saccharomyces cerevisiae.

A. Aguilera, B. Gómez‐González, J. Ruiz, 2011, Methods in molecular biology.

Chromosomal Translocations Caused by Either Pol32-Dependent or Pol32-Independent Triparental Break-Induced Replication

A. Aguilera, B. Gómez‐González, J. Ruiz, 2009, Molecular and Cellular Biology.

Break‐induced RNA–DNA hybrids (BIRDHs) in homologous recombination: friend or foe?

Belén Gómez-González, Andrés Aguilera, A. Aguilera, 2023, EMBO reports.

Harmful DNA:RNA hybrids are formed in cis and in a Rad51-independent manner

A. Aguilera, Juan Lafuente-Barquero, B. Gómez‐González, 2020, bioRxiv.

A CDK-regulated chromatin segregase promoting chromosome replication

Christoph F. Kurat, A. Cheung, K. Reusswig, 2020, Nature Communications.

DNA–RNA hybrids: the risks of DNA breakage during transcription

A. Aguilera, B. Gómez‐González, Belén Gómez‐González, 2017, Nature Structural &Molecular Biology.

Editorial: The Role of RNA in Genome Stability: To Wreck or Repair?

Wenyi Feng, A. Dutta, B. Gómez‐González, 2022, Frontiers in Molecular Biosciences.

BRCA2 promotes DNA‐RNA hybrid resolution by DDX5 helicase at DNA breaks to facilitate their repair ‡

Bérangère Lombard, D. Loew, Juan S. Martinez, 2021, The EMBO journal.

DNA-RNA hybrids at DSBs interfere with repair by homologous recombination

A. Aguilera, Ana G Rondón, A. Rondón, 2021, eLife.

The DNA damage response acts as a safeguard against harmful DNA–RNA hybrids of different origins

A. Aguilera, M. García-Rubio, Sonia I. Barroso, 2019, EMBO reports.

The Role of Replication-Associated Repair Factors on R-Loops

A. Aguilera, Vaibhav Bhatia, B. Gómez‐González, 2017, Genes.

Histone Mutants Separate R Loop Formation from Genome Instability Induction.

A. Aguilera, M. García-Rubio, Ana G Rondón, 2017, Molecular cell.

The S-Phase Checkpoint Is Required To Respond to R-Loops Accumulated in THO Mutants

B. Gómez-González, A. Aguilera, Irene Felipe-Abrio, 2009, Molecular and Cellular Biology.

A role for the Saccharomyces cerevisiae Rtt109 histone acetyltransferase in R-loop homeostasis and associated genome instability

F. Antequera, Alicia García, A. Aguilera, 2022, Genetics.

Human DNA topoisomerase I poisoning causes R loop–mediated genome instability attenuated by transcription factor IIS

Jessica Marinello, Marco Russo, Sara Morelli, 2024, Science advances.

RNA biogenesis and RNA metabolism factors as R-loop suppressors: a hidden role in genome integrity

R. Luna, Belén Gómez-González, A. Aguilera, 2024, Genes & development.

Rpd3L and Hda1 histone deacetylases facilitate repair of broken forks by promoting sister chromatid cohesion

B. Gómez-González, A. Aguilera, Pedro Ortega, 2019, Nature Communications.