D. Higgs

发表

Dissection of the 4D chromatin structure of the α-globin locus through in vivo erythroid differentiation with extreme spatial and temporal resolution

Daniel Hidalgo, M. Socolovsky, Matthew E. Gosden, 2019, bioRxiv.

Genetic dissection of the α-globin super-enhancer in vivo

L. Pennacchio, J. Telenius, J. Hughes, 2016, Nature Genetics.

In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction

S. Orkin, N. Andrews, D. Higgs, 1992, Molecular and cellular biology.

A revised model for promoter competition based on multi-way chromatin interactions at the α-globin locus

J. Hughes, D. Higgs, A. M. Oudelaar, 2019, Nature Communications.

Loop extrusion by cohesin plays a key role in enhancer-activated gene expression during differentiation

D. Downes, J. Hughes, Robert A. Beagrie, 2023, bioRxiv.

ATR16 Syndrome: Mechanisms Linking Monosomy to Phenotype

A. Wilkie, D. Higgs, J. Traeger-Synodinos, 2019, bioRxiv.

Generation of bivalent chromatin domains during cell fate decisions

P. Vyas, T. Enver, S. Jacobsen, 2011, Epigenetics & Chromatin.

Super-enhancers include classical enhancers and facilitators to fully activate gene expression

J. Boeke, Brendan R. Camellato, Lucy J. Cornell, 2023, Cell.

Single-cell chromatin interactions reveal regulatory hubs in dynamic compartmentalized domains

J. Dekker, J. Telenius, R. Schwessinger, 2018, bioRxiv.

The characteristics of CTCF binding sequences contribute to enhancer blocking activity

Lucy J. Cornell, Mira T. Kassouf, Helena S. Francis, 2023, bioRxiv.

Ancient genomic linkage couples metabolism with erythroid development

Robert A. Beagrie, H. Drakesmith, A. Armitage, 2023, bioRxiv.

α-thalassaemia

D. Higgs, C. Harteveld, D. Higgs, 2010, Orphanet Journal of Rare Diseases.