Brian Houston

Impact of Plasma Protein Binding in Drug Clearance Prediction: A Database Analysis of Published Studies and Implications for In Vitro-In Vivo Extrapolation

J. Houston, D. Hallifax, L. Francis, 2020, Drug Metabolism and Disposition.

Utility of Drug Depletion-Time Profiles in Isolated Hepatocytes for Accessing Hepatic Uptake Clearance: Identifying Rate-Limiting Steps and Role of Passive Processes

J. Houston, Emilie Jigorel, Brian Houston, 2012, Drug Metabolism and Disposition.

Evaluation of Recombinant Cytochrome P450 Enzymes as an in Vitro System for Metabolic Clearance Predictions

P. Nicklin, C. Strain-Damerell, R. Stringer, 2009, Drug Metabolism and Disposition.

PREDICTION OF METABOLIC CLEARANCE USING CRYOPRESERVED HUMAN HEPATOCYTES: KINETIC CHARACTERISTICS FOR FIVE BENZODIAZEPINES

J. Houston, D. Hallifax, N. Hakooz, 2005, Drug Metabolism and Disposition.

Comparative Analysis of CYP3A Heteroactivation by Steroid Hormones and Flavonoids in Different in Vitro Systems and Potential in Vivo Implications

A. Galetin, A. Harrison, J. Henshall, 2008, Drug Metabolism and Disposition.