Colin. J. Henderson

发表

An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials

C. Wolf, L. Stanley, N. Scheer, 2019, Drug Metabolism and Disposition.

Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans[S]

C. Brocker, C. Wolf, F. Gonzalez, 2016, Journal of Lipid Research.

Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors.

P. Couttet, D. Theil, H. Ellinger-Ziegelbauer, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

Defining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse Model

C. Wolf, D. Busch, S. Oswald, 2015, Drug Metabolism and Disposition.

Microsoft Word-64262667-file00

D. Busch, S. Oswald, N. Scheer, 2015 .

Hepatic cytochrome P-450 reductase-null mice show reduced transcriptional response to quercetin and reveal physiological homeostasis between jejunum and liver.

C Roland Wolf, Gary Williamson, Sofiane Lariani, 2006, American journal of physiology. Gastrointestinal and liver physiology.

Evidence That Cytochrome b5 and Cytochrome b5 Reductase Can Act as Sole Electron Donors to the Hepatic Cytochrome P450 System

C. Wolf, L. Mclaughlin, Colin. J. Henderson, 2013, Molecular Pharmacology.

NADPH–Cytochrome P450 Oxidoreductase: Roles in Physiology, Pharmacology, and Toxicology

R. Finn, C. Wolf, C. Flück, 2013, Drug Metabolism and Disposition.

Exposure to benzo[a]pyrene of Hepatic Cytochrome P450 Reductase Null (HRN) and P450 Reductase Conditional Null (RCN) mice: Detection of benzo[a]pyrene diol epoxide-DNA adducts by immunohistochemistry and 32P-postlabelling.

V. Arlt, M. Stiborová, Kaarthik John, 2012, Toxicology letters.

Defining the in Vivo Role for Cytochrome b5 in Cytochrome P450 Function through the Conditional Hepatic Deletion of Microsomal Cytochrome b5*S⃞

R. Finn, J. Houston, C. Wolf, 2008, Journal of Biological Chemistry.

Cytochrome b 5 is a major determinant of human cytochrome P450 CYP2D6 & CYP3A4 activity in vivo

N. Scheer, Colin J. Henderson, L. McLaughlin, 2015 .

Deletion of 30 Murine Cytochrome P450 Genes Results In Viable Mice With Compromised Drug Metabolism

C. Wolf, N. Scheer, C. Henderson, 2014, Drug Metabolism and Disposition.

A Role for Cytochrome b5 in the In Vivo Disposition of Anticancer and Cytochrome P450 Probe Drugs in Mice

R. Finn, C. Wolf, Sébastien Ronseaux, 2014, Drug Metabolism and Disposition.

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V. Arlt, E. Frei, M. Stiborová, 2022 .