John Sinclair

发表

Human cytomegalovirus immediate-early 2 (IE2) protein can transactivate the human hsp70 promoter by alleviation of Dr1-mediated repression

R. Caswell, J. Sinclair, L. Bryant, 1996, Journal of virology.

Functional interaction between the HCMV IE2 transactivator and the retinoblastoma protein.

T. Kouzarides, R. Caswell, G. Hayhurst, 1994, The EMBO journal.

The human cytomegalovirus 86K immediate early (IE) 2 protein requires the basic region of the TATA-box binding protein (TBP) for binding, and interacts with TBP and transcription factor TFIIB via regions of IE2 required for transcriptional regulation.

T. Kouzarides, G. Hayward, C. Chiou, 1993, The Journal of general virology.

The human cytomegalovirus 80-kilodalton but not the 72-kilodalton immediate-early protein transactivates heterologous promoters in a TATA box-dependent mechanism and interacts directly with TFIID

T. Kouzarides, R. Caswell, J. Sinclair, 1992, Journal of virology.

Repression of human cytomegalovirus gene expression associated with a novel immediate early regulatory region binding factor.

J. Sissons, J. Sinclair, S. Kothari, 1989, Nucleic acids research.

The human cytomegalovirus IE1-72 protein interacts with the cellular p107 protein and relieves p107-mediated transcriptional repression of an E2F-responsive promoter

E. Huang, T. Kowalik, L. Zhu, 1996, Journal of virology.

Human cytomegalovirus infection inhibits epidermal growth factor (EGF) signalling by targeting EGF receptors.

J. Fairley, M. Bain, John Sinclair, 2002, Journal of General Virology.

Human cytomegalovirus mediates cell cycle progression through G(1) into early S phase in terminally differentiated cells.

R. Caswell, J. Sinclair, J. Baillie, 2000, The Journal of general virology.

Repression of the major immediate early promoter of human cytomegalovirus allows transcription from an alternate promoter.

Mark R. Wills, John Sinclair, Rebecca Mason, 2023, The Journal of general virology.

Aspects of human cytomegalovirus latency and reactivation.

M. Reeves, J. Sinclair, John Sinclair, 2008, Current topics in microbiology and immunology.