Patrick Fitzgerald

发表

ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences

D. Green, Mao Yang, P. Fitzgerald, 2017, Cell.

Disruption of Mitochondrial Function during Apoptosis Is Mediated by Caspase Cleavage of the p75 Subunit of Complex I of the Electron Transport Chain

Mark H Ellisman, Cristina Muñoz-Pinedo, Guy A Perkins, 2004, Cell.

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation.

D. Green, H. Chi, D. Finkelstein, 2011, Immunity.

Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis

D. Green, A. Oberst, C. Dillon, 2015, Cell Death and Differentiation.

Different mitochondrial intermembrane space proteins are released during apoptosis in a manner that is coordinately initiated but can vary in duration.

Cristina Muñoz-Pinedo, D. Green, D. Newmeyer, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Cell death and tissue remodeling in planarian regeneration.

D. Green, A. Sánchez Alvarado, P. Fitzgerald, 2010, Developmental biology.

Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis.

D. Green, J. Crawford, P. Fitzgerald, 2020, Immunity.

Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice

D. Green, N. Droin, P. Fitzgerald, 2006, Nature.

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

D. Green, M. Hengartner, A. Oberst, 2011, Proceedings of the National Academy of Sciences.

BID-induced structural changes in BAK promote apoptosis

D. Green, K. Gehring, F. Llambi, 2013, Nature Structural &Molecular Biology.

Mitochondrial pathway of apoptosis is ancestral in metazoans

D. Green, G. Salvesen, A. Sánchez Alvarado, 2012, Proceedings of the National Academy of Sciences.

Non-apoptotic role of BID in inflammation and innate immunity

Ricardo G. Correa, D. Green, John Calvin Reed, 2011, Nature.

Catalytic activity of the caspase-8-FLIPL complex inhibits RIPK3-dependent necrosis

Guy S. Salvesen, D. Green, G. Salvesen, 2011, Nature.

Sublethal cytochrome c release generates drug-tolerant persister cells

D. Green, J. Crawford, S. Tait, 2022, Cell.

Activation-induced T-cell death is cell cycle dependent and regulated by cyclin B

R. Margolis, R. Fotedar, A. Fotedar, 1995, Molecular and cellular biology.

GAPDH and Autophagy Preserve Survival after Apoptotic Cytochrome c Release in the Absence of Caspase Activation

D. Green, D. Newmeyer, P. Barbry, 2007, Cell.

The cytotoxic cell protease granzyme B initiates apoptosis in a cell‐free system by proteolytic processing and activation of the ICE/CED‐3 family protease, CPP32, via a novel two‐step mechanism.

D. Green, G. Bokoch, Lianfa Shi, 1996, The EMBO journal.

Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling

D. Green, Sunny Shin, A. Oberst, 2014, Proceedings of the National Academy of Sciences.

p53 Induces Apoptosis by Caspase Activation through Mitochondrial Cytochrome c Release*

D. Green, E. Bossy‐Wetzel, M. Schuler, 2000, The Journal of Biological Chemistry.

c-Abl Phosphorylates MFN2 to Regulate Mitochondrial Morphology in Cells under Endoplasmic Reticulum and Oxidative Stress, Impacting Cell Survival and Neurodegeneration

J. Marugan, C. Hetz, N. Inestrosa, 2023, Antioxidants.

Defective Cytochrome c-dependent Caspase Activation in Ovarian Cancer Cell Lines due to Diminished or Absent Apoptotic Protease Activating Factor-1 Activity*

G. Mills, D. Green, M. Schuler, 2001, The Journal of Biological Chemistry.

p21 contains independent binding sites for cyclin and cdk2: both sites are required to inhibit cdk2 kinase activity.

M. Dorée, R. Fotedar, A. Fotedar, 1996, Oncogene.

Noncanonical function of an autophagy protein prevents spontaneous Alzheimer’s disease

D. Green, Stanislav S Zakharenko, P. Fitzgerald, 2020, Science Advances.

Role for Cyclin A-dependent Kinase in DNA Replication in Human S Phase Cell Extracts*

M. Dorée, R. Fotedar, A. Fotedar, 1996, The Journal of Biological Chemistry.

GAPDH and Autophagy Preserve Survival after Apoptotic Cytochrome c Release in the Absence of Caspase Activation

Pascal Barbry, Bernard Mari, D. Green, 2007, Cell.

Cutting Edge: Endoplasmic Reticulum Stress Licenses Macrophages To Produce Mature IL-1β in Response to TLR4 Stimulation through a Caspase-8– and TRIF-Dependent Pathway

D. Green, A. Sher, A. Oberst, 2014, The Journal of Immunology.

The interaction between RIPK1 and FADD controls perinatal lethality and inflammation

J. Crawford, Douglas R. Green, Bart Tummers, 2024, Cell reports.

Inhibition of Hsp90 via 17-DMAG induces apoptosis in a p53-dependent manner to prevent medulloblastoma

F. Zindy, M. Roussel, C. Dillon, 2009, Proceedings of the National Academy of Sciences.

Just So Stories about the Evolution of Apoptosis

D. Green, P. Fitzgerald, Patrick Fitzgerald, 2016, Current Biology.

Presence of a transcriptionally active glucocorticoid receptor alpha in lens epithelial cells.

D. Green, N. Droin, P. Fitzgerald, 2003, Investigative ophthalmology & visual science.

Caspase-8 and FADD prevent spontaneous ZBP1 expression and necroptosis

D. Green, J. Crawford, P. Fitzgerald, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Growth inhibition by CDK-cyclin and PCNA binding domains of p21 occurs by distinct mechanisms and is regulated by ubiquitin-proteasome pathway

D. Rousseau, R. Fotedar, A. Fotedar, 1999, Oncogene.

Role of proteolysis in caspase-8 activation and stabilization.

D. Green, G. Salvesen, P. Fitzgerald, 2007, Biochemistry.