Visvanathan Ramamurthy

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Cone Phosphodiesterase-6γ’ Subunit Augments Cone PDE6 Holoenzyme Assembly and Stability in a Mouse Model Lacking Both Rod and Cone PDE6 Catalytic Subunits

W. Hauswirth, A. Dinculescu, V. Ramamurthy, 2018, Front. Mol. Neurosci..

Leber congenital amaurosis linked to AIPL1: a mouse model reveals destabilization of cGMP phosphodiesterase.

J. Hurley, T. Reh, V. Ramamurthy, 2004, Proceedings of the National Academy of Sciences of the United States of America.

RAS-converting enzyme 1-mediated endoproteolysis is required for trafficking of rod phosphodiesterase 6 to photoreceptor outer segments

M. Bergo, V. Ramamurthy, Saravanan Kolandaivelu, 2011, Proceedings of the National Academy of Sciences.

Gene therapy using self-complementary Y733F capsid mutant AAV2/8 restores vision in a model of early onset Leber congenital amaurosis.

W. Hauswirth, S. Boye, Tiansen Li, 2011, Human molecular genetics.

Rod photoreceptor differentiation in fetal and infant human retina.

A. Hendrickson, J. Provis, V. Ramamurthy, 2008, Experimental eye research.

Early alteration of retinal neurons in Aipl1-/- animals.

Ratnesh K Singh, V. Ramamurthy, Saravanan Kolandaivelu, 2014, Investigative ophthalmology & visual science.

Interactions within the Coiled-coil Domain of RetGC-1 Guanylyl Cyclase Are Optimized for Regulation Rather than for High Affinity*

V. Daggett, J. Hurley, D. Hunt, 2001, The Journal of Biological Chemistry.

Excessive tubulin glutamylation leads to progressive cone-rod dystrophy and loss of outer segment integrity.

Scott Rhodes, Rawaa Aljammal, Thamaraiselvi Saravanan, 2024, Human molecular genetics.

Mutations in ARL2BP, a protein required for ciliary microtubule structure, cause syndromic male infertility in humans and mice

C. Rivolta, E. Tucker, V. Ramamurthy, 2019, PLoS genetics.

Proteoglycan IMPG2 Shapes the Interphotoreceptor Matrix and Modulates Vision

V. Ramamurthy, Ezequiel M. Salido, Visvanathan Ramamurthy, 2019, The Journal of Neuroscience.

Rhodopsin signaling mediates light-induced photoreceptor cell death in rd10 mice through a transducin-independent mechanism.

V. Ramamurthy, Daniella Munezero, T. Saravanan, 2019, Human molecular genetics.

Biochemical analysis of a dimerization domain mutation in RetGC-1 associated with dominant cone-rod dystrophy.

J. Hurley, D. Hunt, V. Ramamurthy, 1999, Proceedings of the National Academy of Sciences of the United States of America.

AIPL1, a protein implicated in Leber's congenital amaurosis, interacts with and aids in processing of farnesylated proteins

J. Hurley, T. Reh, V. Ramamurthy, 2003, Proceedings of the National Academy of Sciences of the United States of America.

ARL13B, a Joubert Syndrome-Associated Protein, Is Critical for Retinogenesis and Elaboration of Mouse Photoreceptor Outer Segments

V. Ramamurthy, A. Goldberg, Saravanan Kolandaivelu, 2019, The Journal of Neuroscience.

Development and disease of the photoreceptor cilium

M. Cayouette, V. Ramamurthy, Visvanathan Ramamurthy, 2009, Clinical genetics.

The Zebrafish pob Gene Encodes a Novel Protein Required for Survival of Red Cone Photoreceptor Cells Sequence data from this article have been deposited with the EMBL/GenBank Data Libraries under accession no. AY745978.

Michael R. Taylor, Koichi Kawakami, Peter Carmeliet, 2005, Genetics.

Retinal Organoids derived from hiPSCs of an AIPL1-LCA Patient Maintain Cytoarchitecture despite Reduced levels of Mutant AIPL1

Koray D. Kaya, A. Swaroop, M. Cortón, 2020, Scientific Reports.

Functional characterization of missense mutations at codon 838 in retinal guanylate cyclase correlates with disease severity in patients with autosomal dominant cone-rod dystrophy.

J. Hurley, D. Hunt, S. Bhattacharya, 2000, Human molecular genetics.

AIPL1, a Protein Associated with Childhood Blindness, Interacts with α-Subunit of Rod Phosphodiesterase (PDE6) and Is Essential for Its Proper Assembly*

J. Hurley, V. Ramamurthy, Saravanan Kolandaivelu, 2009, The Journal of Biological Chemistry.

HSP90α is needed for the survival of rod photoreceptors and regulates the expression of rod PDE6 subunits

V. Ramamurthy, Daniella Munezero, T. Guan, 2023, The Journal of biological chemistry.

AIPL1, A protein linked to blindness, is essential for the stability of enzymes mediating cGMP metabolism in cone photoreceptor cells.

Ratnesh K Singh, V. Ramamurthy, Saravanan Kolandaivelu, 2014, Human molecular genetics.

Cone Phosphodiesterase-6α′ Restores Rod Function and Confers Distinct Physiological Properties in the Rod Phosphodiesterase-6β-Deficient rd10 Mouse

W. Hauswirth, S. Boye, A. Dinculescu, 2013, The Journal of Neuroscience.

Greasing the protein biosynthesis machinery of photoreceptor neurons

V. Ramamurthy, Jeffrey Christiansen, Visvanathan Ramamurthy, 2012, Cellular logistics.

Rod Phosphodiesterase-6 (PDE6) Catalytic Subunits Restore Cone Function in a Mouse Model Lacking Cone PDE6 Catalytic Subunit*

V. Ramamurthy, B. Chang, Saravanan Kolandaivelu, 2011, The Journal of Biological Chemistry.

The Leber congenital amaurosis protein, AIPL1, is needed for the viability and functioning of cone photoreceptor cells.

V. Ramamurthy, W. Baehr, A. Goldberg, 2010, Human molecular genetics.

AIPL1 protein and its indispensable role in cone photoreceptor function and survival.

V. Ramamurthy, Saravanan Kolandaivelu, Visvanathan Ramamurthy, 2014, Advances in experimental medicine and biology.

2012 Landes Bioscience. Do not distribute. Greasing the protein biosynthesis machinery of photoreceptor neurons Role for postprenylation processing of proteins

V. Ramamurthy, Jeffrey Christiansen, Visvanathan Ramamurthy, 2012 .

Prominin 1 is crucial for the early development of photoreceptor outer segments

Scott Rhodes, Sila Yanardag, Thamaraiselvi Saravanan, 2024, Scientific reports.

ARL2BP, a protein linked to retinitis pigmentosa, is needed for normal photoreceptor cilia doublets and outer segment structure

Ratnesh K Singh, V. Ramamurthy, A. Goldberg, 2018, Molecular biology of the cell.

Biochemical Function of the LCA Linked Protien, Aryl Hydrocarbon Receptor Interacting Protein Like-1 (AIPL1)

J. Hurley, V. Ramamurthy, M. L. Schwartz, 2006 .

Topology of the Integral Membrane Form of Escherichia coli SecA Protein Reveals Multiple Periplasmically Exposed Regions and Modulation by ATP Binding*

V. Ramamurthy, D. Oliver, Visvanathan Ramamurthy, 1997, The Journal of Biological Chemistry.

Phosphomimetic Mutations Impact Huntingtin Aggregation in the Presence of a Variety of Lipid Systems.

V. Ramamurthy, J. Legleiter, Sharon E. Groover, 2020, Biochemistry.

Deficiency of Isoprenylcysteine Carboxyl Methyltransferase (ICMT) Leads to Progressive Loss of Photoreceptor Function

M. Bergo, S. Young, V. Ramamurthy, 2016, The Journal of Neuroscience.

The mAB 13A4 monoclonal antibody to the mouse PROM1 protein recognizes a structural epitope

P. Stoilov, F. Matalkah, S. Rhodes, 2022, PLoS ONE.

The Musashi 1 Controls the Splicing of Photoreceptor-Specific Exons in the Vertebrate Retina

B. Cieply, P. Stoilov, V. Ramamurthy, 2016, PLoS genetics.

Splice Isoforms of Phosducin-like Protein Control the Expression of Heterotrimeric G Proteins*

P. Stoilov, M. Sokolov, V. Ramamurthy, 2013, The Journal of Biological Chemistry.

Functional analyses of mutant recessive GUCY2D alleles identified in Leber congenital amaurosis patients: protein domain comparisons and dominant negative effects.

J. Hurley, V. Ramamurthy, C. Tucker, 2004, Molecular vision.

Alternative Splicing Shapes the Phenotype of a Mutation in BBS8 To Cause Nonsyndromic Retinitis Pigmentosa

P. Stoilov, Ratnesh K Singh, V. Ramamurthy, 2015, Molecular and Cellular Biology.

Nucleotide Binding Activity of SecA Homodimer Is Conformationally Regulated by Temperature and Altered byprlD and azi Mutations*

V. Ramamurthy, H. Ding, I. Mukerji, 2000, The Journal of Biological Chemistry.

Mutations inPNPLA6are linked to photoreceptor degeneration and various forms of childhood

D. Sharon, Rui Chen, P. Chinnery, 2015 .