Germán Perdomo

发表

Central Proliferation and Neurogenesis Is Impaired in Type 2 Diabetes and Prediabetes Animal Models

M. Garcia-Alloza, I. Cózar-Castellano, M. Jiménez-Palomares, 2014, PloS one.

Differential central pathology and cognitive impairment in pre-diabetic and diabetic mice

T. Spires-Jones, M. Garcia-Alloza, I. Cózar-Castellano, 2013, Psychoneuroendocrinology.

Increased Aβ production prompts the onset of glucose intolerance and insulin resistance.

M. Garcia-Alloza, I. Cózar-Castellano, M. Jiménez-Palomares, 2012, American journal of physiology. Endocrinology and metabolism.

The role of nitrate reductase in the regulation of the nitrate assimilation pathway in the yeast Hansenula polymorpha.

G. Perdomo, A. Lancha, F. Machín, 2003, FEMS yeast research.

Primary Cilia in Pancreatic β- and α-Cells: Time to Revisit the Role of Insulin-Degrading Enzyme

I. Cózar-Castellano, M. Pablos, G. Perdomo, 2022, Frontiers in Endocrinology.

Inhibition of Fatty Acid Metabolism Reduces Human Myeloma Cells Proliferation

I. Cózar-Castellano, G. Perdomo, J. Tirado-Vélez, 2012, PloS one.

Hepatic Insulin Clearance: Mechanism and Physiology.

S. Najjar, G. Perdomo, Germán Perdomo, 2019, Physiology.

Rapamycin-mediated inhibition of mammalian target of rapamycin in skeletal muscle cells reduces glucose utilization and increases fatty acid oxidation.

G. Perdomo, N. Brown, I. Sipula, 2006, Metabolism: clinical and experimental.

Fatty Acid-induced Insulin Resistance in L6 Myotubes Is Prevented by Inhibition of Activation and Nuclear Localization of Nuclear Factor κB*

R. O’Doherty, G. Perdomo, N. Brown, 2004, Journal of Biological Chemistry.

Proteomic analysis of fructose-induced fatty liver in hamsters.

S. Ringquist, M. Trucco, G. Perdomo, 2008, Metabolism: clinical and experimental.

FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in mice.

M. Meseck, G. Perdomo, H. H. Dong, 2008, The Journal of clinical investigation.

A moderate increase in carnitine palmitoyltransferase 1a activity is sufficient to substantially reduce hepatic triglyceride levels.

R. O’Doherty, G. Perdomo, N. Brown, 2008, American journal of physiology. Endocrinology and metabolism.

Targeting Insulin-Degrading Enzyme in Insulin Clearance

M. Leissring, G. Perdomo, B. Merino, 2021, International journal of molecular sciences.

Modulation of Insulin Sensitivity by Insulin-Degrading Enzyme

I. Cózar-Castellano, M. Leissring, G. Perdomo, 2021, Biomedicines.

Intestinal Fructose and Glucose Metabolism in Health and Disease

I. Cózar-Castellano, G. Perdomo, B. Merino, 2019, Nutrients.

Increased β-Oxidation in Muscle Cells Enhances Insulin-stimulated Glucose Metabolism and Protects against Fatty Acid-induced Insulin Resistance Despite Intramyocellular Lipid Accumulation*

B. Corkey, S. Adams, S. Commerford, 2004, Journal of Biological Chemistry.

Prepregnancy body mass index influences lipid oxidation rate during pregnancy

R. Torrejón, G. Perdomo, J. Bartha, 2017, Acta obstetricia et gynecologica Scandinavica.

Cembranoids from Eunicea sp. enhance insulin-producing cells proliferation

I. Cózar-Castellano, J. Darias, G. Perdomo, 2018 .

A role of apolipoprotein D in triglyceride metabolism[S]

Dae Hyun Kim, Ting Zhang, S. Qu, 2010, Journal of Lipid Research.

Altered Surface Expression of Insulin-Degrading Enzyme on Monocytes and Lymphocytes from COVID-19 Patients Both at Diagnosis and after Hospital Discharge

D. Bernardo, G. Perdomo, A. Fiz-López, 2022, International journal of molecular sciences.

Effects of apoA-V on HDL and VLDL metabolism in APOC3 transgenic mice1 Published, JLR Papers in Press, April 16, 2007.

G. Perdomo, H. H. Dong, S. Qu, 2007, Journal of Lipid Research.

Manipulation of Transmembrane Transport by Synthetic K+ Ionophore Depsipeptides and Its Implications in Glucose-Stimulated Insulin Secretion in β-Cells.

I. Cózar-Castellano, M. Barboiu, T. Torroba, 2019, Chemistry.

Aberrant Forkhead box O1 function is associated with impaired hepatic metabolism.

J. Altomonte, M. Meseck, G. Perdomo, 2006, Endocrinology.

Targeted delivery of HGF to the skeletal muscle improves glucose homeostasis in diet-induced obese mice

I. Cózar-Castellano, A. García-Ocaña, Viviana Sánchez-Encinales, 2015, Journal of Physiology and Biochemistry.

Hepatocyte growth factor is elevated in amniotic fluid from obese women and regulates placental glucose and fatty acid metabolism.

I. Cózar-Castellano, G. Perdomo, J. Bartha, 2015, Placenta.

Hepatocyte growth factor as an indicator of neonatal maturity

G. Jiménez-Gómez, I. Benavente-Fernández, G. Perdomo, 2013, Journal of pediatric endocrinology & metabolism : JPEM.

Hepatocyte growth factor is elevated in amniotic fluid from obese 1 women and regulates placental glucose and fatty acid metabolism

I. Cózar-Castellano, G. Perdomo, J. Bartha, 2015 .

LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus

J. P. Florido, P. Meda, M. Bugliani, 2018, Nature Communications.

Cloning, sequencing, and expression of H.a.YNR1 and H.a.YNI1, encoding nitrate and nitrite reductases in the yeast Hansenula anomala

G. Perdomo, J. M. de la Rosa, N. Brito, 2000, Yeast.

Pancreatic beta-cell-specific deletion of insulin-degrading enzyme leads to dysregulated insulin secretion and beta-cell functional immaturity.

I. Cózar-Castellano, M. Leissring, P. Cidad, 2019, American journal of physiology. Endocrinology and metabolism.

High glucose levels reduce fatty acid oxidation and increase triglyceride accumulation in human placenta.

I. Cózar-Castellano, G. Perdomo, J. Bartha, 2013, American journal of physiology. Endocrinology and metabolism.

FoxO6 Integrates Insulin Signaling With Gluconeogenesis in the Liver

S. Ringquist, S. Strom, G. Perdomo, 2011, Diabetes.

FoxO1 Links Insulin Resistance to Proinflammatory Cytokine IL-1β Production in Macrophages

Yi Lu, Jian Zhang, J. Piganelli, 2009, Diabetes.

Novel proapoptotic effect of hepatocyte growth factor: synergy with palmitate to cause pancreatic {beta}-cell apoptosis.

J. Dubé, K. Takane, R. Vasavada, 2010, Endocrinology.

Cyclin C stimulates β-cell proliferation in rat and human pancreatic β-cells.

I. Cózar-Castellano, E. Bernal-Mizrachi, M. Jiménez-Palomares, 2015, American journal of physiology. Endocrinology and metabolism.

Epoxypukalide Induces Proliferation and Protects against Cytokine-Mediated Apoptosis in Primary Cultures of Pancreatic β-Cells

I. Cózar-Castellano, M. Jiménez-Palomares, G. Perdomo, 2013, PloS one.

Insulin-degrading enzyme ablation in mouse pancreatic alpha cells triggers cell proliferation, hyperplasia and glucagon secretion dysregulation

K. Kaestner, I. Cózar-Castellano, M. Leissring, 2022, Diabetologia.

Effects of Fasting and Feeding on Transcriptional and Posttranscriptional Regulation of Insulin-Degrading Enzyme in Mice

I. Cózar-Castellano, M. Leissring, G. Perdomo, 2021, Cells.

The mammalian target of rapamycin regulates lipid metabolism in primary cultures of rat hepatocytes.

G. Perdomo, N. Brown, I. Sipula, 2007, Metabolism: clinical and experimental.

Protective effects of epoxypukalide on pancreatic β-cells and glucose metabolism in STZ-induced diabetic mice

I. Cózar-Castellano, G. Perdomo, A. Díaz-Marrero, 2015, Islets.

Hepatocyte Growth Factor Is a Novel Stimulator of Glucose Uptake and Metabolism in Skeletal Muscle Cells*

A. García-Ocaña, R. O’Doherty, G. Perdomo, 2008, Journal of Biological Chemistry.

Chloro-Furanocembranolides from Leptogorgia sp. Improve Pancreatic Beta-Cell Proliferation

I. Cózar-Castellano, J. Darias, J. M. de la Rosa, 2018, Marine drugs.