Dorit Trudler

发表

Parkinson’s disease: what the model systems have taught us so far

R. Ambasudhan, Swagata Ghatak, Nima Dolatabadi, 2018, Journal of Genetics.

Emerging hiPSC Models for Drug Discovery in Neurodegenerative Diseases

S. Lipton, Swagata Ghatak, D. Trudler, 2021, International journal of molecular sciences.

Novel Direct Conversion of Microglia to Neurons.

S. Lipton, Dorit Trudler, 2019, Trends in molecular medicine.

Mechanistic insight into female predominance in Alzheimer’s disease based on aberrant protein S-nitrosylation of C3

S. Lipton, S. Tannenbaum, Tomohiro Nakamura, 2022, Science advances.

DJ‐1 deficiency triggers microglia sensitivity to dopamine toward a pro‐inflammatory phenotype that is attenuated by rasagiline

S. Mandel, M. Youdim, D. Frenkel, 2014, Journal of neurochemistry.

DJ‐1 deficiency impairs autophagy and reduces alpha‐synuclein phagocytosis by microglia

D. Frenkel, D. Trudler, R. Pinkas-Kramarski, 2017, Journal of neurochemistry.

Astrocytes from old Alzheimer's disease mice are impaired in Aβ uptake and in neuroprotection

A. Barzilai, P. Blinder, Tal Iram, 2016, Neurobiology of Disease.

New insights on Parkinson’s disease genes: the link between mitochondria impairment and neuroinflammation

D. Frenkel, D. Trudler, Y. Nash, 2015, Journal of Neural Transmission.

γ‐Secretase component presenilin is important for microglia β‐amyloid clearance

D. Farfara, D. Frenkel, D. Trudler, 2011, Annals of neurology.

Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection

Rommie E. Amaro, S. Lipton, J. Diedrich, 2022, Nature Chemical Biology.

Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation

S. Lipton, M. Karin, W. Tourtellotte, 2021, Immunity.

MEF2D haploinsufficiency downregulates the NRF2 pathway and renders photoreceptors susceptible to light-induced oxidative stress

S. Lipton, J. Yates, S. Mckercher, 2017, Proceedings of the National Academy of Sciences.

Low-Level Laser Therapy Ameliorates Disease Progression in a Mouse Model of Alzheimer’s Disease

U. Oron, R. Vassar, D. Farfara, 2015, Journal of Molecular Neuroscience.

Targeted protein S-nitrosylation of ACE2 as potential treatment to prevent spread of SARS-CoV-2 infection

Rommie E. Amaro, S. Lipton, J. Diedrich, 2022, bioRxiv.

Potential Therapeutic Use of the Rosemary Diterpene Carnosic Acid for Alzheimer’s Disease, Parkinson’s Disease, and Long-COVID through NRF2 Activation to Counteract the NLRP3 Inflammasome

S. Lipton, T. Satoh, D. Trudler, 2022, Antioxidants.

Physiological expression of mutated TAU impaired astrocyte activity and exacerbates β-amyloid pathology in 5xFAD mice

H. Eldar-Finkelman, L. Avrahami, D. Farfara, 2023, Journal of Neuroinflammation.

Phenylalanine assembly into toxic fibrils suggests amyloid etiology in phenylketonuria.

A. Caflisch, L. Adler-Abramovich, E. Gazit, 2012, Nature chemical biology.