J. A. Westwood

发表

Genetic redirection of T cells for cancer therapy

M. Kershaw, J. Westwood, J. A. Westwood, 2010, Journal of leukocyte biology.

Enhancing adoptive immunotherapy of cancer

P. Darcy, M. Kershaw, J. Westwood, 2010, Expert Opinion on Biological Therapy.

Engineering T Cell Function Using Chimeric Antigen Receptors Identified Using a DNA Library Approach

P. Darcy, M. Kershaw, C. Duong, 2013, PloS one.

Interleukin 21 enhances antibody-mediated tumor rejection.

M. Smyth, K. Takeda, H. Yagita, 2008, Cancer research.

Antitumor activity of dual-specific T cells and influenza virus

P. Hwu, M. Smyth, P. Darcy, 2007, Cancer Gene Therapy.

Combination anti-CD137 and anti-CD40 antibody therapy in murine myc-driven hematological cancers.

P. L. Bergsagel, R. Johnstone, P. Darcy, 2014, Leukemia research.

Adoptive transfer of T cells modified with a humanized chimeric receptor gene inhibits growth of Lewis-Y-expressing tumors in mice.

A. Scott, J. Trapani, M. Smyth, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Expansion and characterization of T cells transduced with a chimeric receptor against ovarian cancer.

S. Rosenberg, P. Hwu, M. Dudley, 2000, Human gene therapy.

Activation of NK cell cytotoxicity.

M. Smyth, M. Degli-Esposti, E. Cretney, 2005, Molecular immunology.

Combined natural killer T-cell based immunotherapy eradicates established tumors in mice.

G. Besra, M. Smyth, P. Darcy, 2007, Cancer research.

Persistence and efficacy of second generation CAR T cell against the LeY antigen in acute myeloid leukemia.

A. Scott, J. Trapani, M. Smyth, 2013, Molecular therapy : the journal of the American Society of Gene Therapy.

Gene modification strategies to induce tumor immunity.

P. Darcy, M. Kershaw, J. Westwood, 2005, Immunity.

Routes of Delivery for CpG and Anti-CD137 for the Treatment of Orthotopic Kidney Tumors in Mice

P. Darcy, R. Hicks, M. Kershaw, 2014, PloS one.

A Phase I Study on Adoptive Immunotherapy Using Gene-Modified T Cells for Ovarian Cancer

Gang Wang, Steven A. Rosenberg, Zelig Eshhar, 2006, Clinical Cancer Research.

Three agonist antibodies in combination with high-dose IL-2 eradicate orthotopic kidney cancer in mice

M. Smyth, P. Darcy, M. Kershaw, 2010, Journal of Translational Medicine.

Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2.

F. Marincola, P. Hwu, E. Wang, 2002, Human gene therapy.

Tissues in different anatomical sites can sculpt and vary the tumor microenvironment to affect responses to therapy.

S. Stacker, M. Smyth, P. Darcy, 2014, Molecular therapy : the journal of the American Society of Gene Therapy.

Host perforin reduces tumor number but does not increase survival in oncogene-driven mammary adenocarcinoma.

P. Musiani, M. Smyth, M. Iezzi, 2007, Cancer research.

Dual-specific T cells combine proliferation and antitumor activity

P. Hwu, M. Kershaw, J. Westwood, 2002, Nature Biotechnology.

Generation of gene-modified T cells reactive against the angiogenic kinase insert domain-containing receptor (KDR) found on tumor vasculature.

P. Hwu, J. Westwood, M. Kershaw, 2000, Human gene therapy.

Autoimmunity associated with immunotherapy of cancer.

P. Darcy, M. Kershaw, Sally M. Amos, 2011, Blood.

Multiplex immunohistochemistry accurately defines the immune context of metastatic melanoma

P. Darcy, A. Behren, M. Kershaw, 2018, Scientific Reports.

Immune modulation of the tumor microenvironment for enhancing cancer immunotherapy

P. Darcy, M. Kershaw, J. Westwood, 2013, Oncoimmunology.

Cutting Edge: Tumor Rejection Mediated by NKG2D Receptor-Ligand Interaction Is Dependent upon Perforin1

M. Smyth, P. Darcy, A. Diefenbach, 2002, The Journal of Immunology.

Tumor ablation by gene-modified T cells in the absence of autoimmunity.

J. Trapani, J. Malaterre, M. Smyth, 2010, Cancer research.

Generating CAR T cells from tumor-infiltrating lymphocytes

P. Darcy, M. Kershaw, J. Westwood, 2021, Therapeutic advances in vaccines and immunotherapy.

Expression of a Chimeric Antigen Receptor in Multiple Leukocyte Lineages in Transgenic Mice

J. Schröder, A. Papenfuss, P. Darcy, 2015, PloS one.

Toll-Like Receptor Triggering and T-Cell Costimulation Induce Potent Antitumor Immunity in Mice

R. Schwendener, M. Smyth, P. Darcy, 2009, Clinical Cancer Research.

Anti-Tumor Activity of Genetically Redirected T Cells Against Orthotopic Kidney Cancer in Mice~!2010-01-06~!2010-03-24~!2010-05-13~!

M. Smyth, Yuekang Xu, P. Darcy, 2010 .

The Lewis-Y Carbohydrate Antigen is Expressed by Many Human Tumors and Can Serve as a Target for Genetically Redirected T cells Despite the Presence of Soluble Antigen in Serum

M. Trivett, A. Scott, J. Trapani, 2009, Journal of immunotherapy.

Study on Adoptive Immunotherapy Using Gene-Modified TCells for Ovarian Cancer

S. Rosenberg, P. Hwu, S. Canevari, 2006 .

Enhancing immunotherapy using chemotherapy and radiation to modify the tumor microenvironment

P. Darcy, M. Kershaw, J. Westwood, 2013, Oncoimmunology.

Mobilization of Dendritic Cell Precursors in Patients With Cancer by Flt3 Ligand Allows the Generation of Higher Yields of Cultured Dendritic Cells

S. Rosenberg, P. Hwu, A. Mixon, 2002, Journal of immunotherapy.

Adoptive immunotherapy combined with intratumoral TLR agonist delivery eradicates established melanoma in mice

M. Smyth, P. Darcy, N. Restifo, 2011, Cancer Immunology, Immunotherapy.

Cutting Edge: TRAIL Deficiency Accelerates Hematological Malignancies1

M. Smyth, M. Iezzi, E. Cretney, 2005, The Journal of Immunology.

Gene-engineered T cells for cancer therapy

P. Darcy, M. Kershaw, J. Westwood, 2013, Nature Reviews Cancer.

Cross-talk between tumors can affect responses to therapy

R. Schwendener, P. Darcy, P. Beavis, 2015, Oncoimmunology.

Oncolytic virus and anti-4-1BB combination therapy elicits strong antitumor immunity against established cancer.

J. Flynn, M. Smyth, P. Darcy, 2012, Cancer research.

Clinical application of genetically modified T cells in cancer therapy

P. Darcy, M. Kershaw, J. Westwood, 2014, Clinical & translational immunology.

Absence of retroviral vector-mediated transformation of gene-modified T cells after long-term engraftment in mice

M. Trivett, A. Scott, J. Trapani, 2008, Gene Therapy.

T-cell clones from melanoma patients immunized against an anchor-modified gp100 peptide display discordant effector phenotypes.

S. Rosenberg, M. Dudley, J. Wunderlich, 2000, Cancer journal.

Chimeric antigen receptor-redirected T cells display multifunctional capacity and enhanced tumor-specific cytokine secretion upon secondary ligation of chimeric receptor.

P. Darcy, M. Kershaw, C. Duong, 2013, Immunotherapy.

Dual-specific Chimeric Antigen Receptor T Cells and an Indirect Vaccine Eradicate a Variety of Large Solid Tumors in an Immunocompetent, Self-antigen Setting

D. Tscharke, J. Trapani, S. Rosenberg, 2016, Clinical Cancer Research.

Adenocarcinoma Increase Survival in Oncogene-Driven Mammary Host Perforin Reduces Tumor Number but Does Not

P. Musiani, M. Smyth, M. Iezzi, 2007 .

Mobile Health Intervention to Increase Oral Cancer Therapy Adherence in Patients With Chronic Myeloid Leukemia (The REMIND System): Clinical Feasibility and Acceptability Assessment

P. Butow, L. Cavedon, S. Aranda, 2017, JMIR mHealth and uHealth.

Environmental enrichment does not impact on tumor growth in mice

P. Darcy, M. Kershaw, J. A. Westwood, 2013, F1000Research.

Hematological Malignancies Cutting Edge: TRAIL Deficiency Accelerates

M. Smyth, M. Iezzi, E. Cretney, 2013 .

Sustained antigen-specific antitumor recall response mediated by gene-modified CD4+ T helper-1 and CD8+ T cells.

J. Trapani, M. Smyth, P. Darcy, 2007, Cancer research.