Roger L. Williams

Molecular basis for differential activation of p101 and p84 complexes of PI3Kγ by Ras and GPCRs

Roger L. Williams, M. Rathinaswamy, U. Dalwadi, 2022, bioRxiv.

Dynamics of the Phosphoinositide 3-Kinase p110δ Interaction with p85α and Membranes Reveals Aspects of Regulation Distinct from p110α

Roger L. Williams, J. Burke, O. Perisic, 2011, Structure.

Structural insights into the activation of ataxia-telangiectasia mutated by oxidative stress

O. Perisic, Roger L. Williams, Anna C. Howes, 2023, Science Advances.

Regulation of a Coupled MARCKS-PI3K Lipid Kinase Circuit by Calmodulin: Single-Molecule Analysis of a Membrane-Bound Signaling Module.

Roger L. Williams, J. Burke, J. Falke, 2016, Biochemistry.

The p110delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors.

K. Shokat, C. Rommel, J. Shaw, 2010, Nature chemical biology.