Marina Holgado-Madruga

发表

The Tyrosine Phosphatase SHP-2 Is Required for Sustained Activation of Extracellular Signal-Regulated Kinase and Epithelial Morphogenesis Downstream from the Met Receptor Tyrosine Kinase

C. Maroun, M. Naujokas, Morag Park, 2000, Molecular and Cellular Biology.

The Gab1 PH Domain Is Required for Localization of Gab1 at Sites of Cell-Cell Contact and Epithelial Morphogenesis Downstream from the Met Receptor Tyrosine Kinase

Morag Park, C. Maroun, M. Naujokas, 1999, Molecular and Cellular Biology.

Gab1 Is an Integrator of Cell Death versus Cell Survival Signals in Oxidative Stress

Marina Holgado-Madruga, Albert J. Wong, A. Wong, 2003, Molecular and Cellular Biology.

Elevated JNK activation contributes to the pathogenesis of human brain tumors

Mehdi Tnani, Andrew K Godwin, A. Godwin, 2002, Oncogene.

Targeting a glioblastoma cancer stem-cell population defined by EGF receptor variant III.

K. Jensen, H. Vogel, Shuang-yin Han, 2014, Cancer research.

A Conserved Inositol Phospholipid Binding Site within the Pleckstrin Homology Domain of the Gab1 Docking Protein Is Required for Epithelial Morphogenesis*

C. Maroun, M. Naujokas, Morag Park, 1999, The Journal of Biological Chemistry.

c-Jun NH2-Terminal Kinase 2α2 Promotes the Tumorigenicity of Human Glioblastoma Cells

Shuang-yin Han, J. Cui, A. Wong, 2006 .

Intermediate Molecular Phenotypes to Identify Genetic Markers of Anthracycline-Induced Cardiotoxicity Risk

D. Lambrechts, A. González-Neira, G. Pita, 2023, Cells.

Frequent expression of a mutant epidermal growth factor receptor in multiple human tumors.

J. Biegel, A. Godwin, P. Zoltick, 1995, Cancer research.

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

A. Godwin, A. Wong, M. Holgado-Madruga, 1996, Nature.

The Role of GAB1 in Cancer

J. Pérez-Losada, M. Holgado-Madruga, M. J. Pérez-Baena, 2023, Cancers.

The Scaffolding Adapter Gab1 Mediates Vascular Endothelial Growth Factor Signaling and Is Required for Endothelial Cell Migration and Capillary Formation*

R. Stenne, C. Chabot, Mélanie Laramée, 2007, Journal of Biological Chemistry.

The Gab1 Protein Is a Docking Site for Multiple Proteins Involved in Signaling by the B Cell Antigen Receptor*

M. Gold, R. Ingham, A. Wong, 1998, The Journal of Biological Chemistry.

Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor.

A. Wong, D K Moscatello, A J Wong, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Association of the Multisubstrate Docking Protein Gab1 with the Hepatocyte Growth Factor Receptor Requires a Functional Grb2 Binding Site Involving Tyrosine 1356*

M. Tremblay, D. Kamikura, C. Maroun, 1997, The Journal of Biological Chemistry.

Efficient Cellular Transformation by the Met Oncoprotein Requires a Functional Grb2 Binding Site and Correlates with Phosphorylation of the Grb2-associated Proteins, Cbl and Gab1*

D. Kamikura, Morag Park, E. Fixman, 1997, The Journal of Biological Chemistry.

The Gab1 Docking Protein Links the B Cell Antigen Receptor to the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway and to the SHP2 Tyrosine Phosphatase*

M. Gold, C. Maroun, M. Dang-Lawson, 2001, The Journal of Biological Chemistry.

Constitutive Activation of Phosphatidylinositol 3-Kinase by a Naturally Occurring Mutant Epidermal Growth Factor Receptor*

R. B. Montgomery, A. Wong, M. Holgado-Madruga, 1998, The Journal of Biological Chemistry.

Intermediate molecular phenotypes to identify genetic markers of anthracycline-induced cardiotoxicity risk

D. Lambrechts, A. González-Neira, G. Pita, 2023, bioRxiv.

Constitutively active forms of c-Jun NH2-terminal kinase are expressed in primary glial tumors.

I. Okamoto, A. Wong, Kim T Vo, 2003, Cancer research.

Expression of OVCA1, a candidate tumor suppressor, is reduced in tumors and inhibits growth of ovarian cancer cells.

A. Godwin, W. Bruening, D. C. Schultz, 1999, Cancer research.

Expression of OVCA 1 , a Candidate Tumor Suppressor , Is Reduced in Tumors and Inhibits Growth of Ovarian Cancer Cells 1

A. Godwin, W. Bruening, D. C. Schultz, 1999 .

Pathophysiological Integration of Metabolic Reprogramming in Breast Cancer

M. Mendiburu-Eliçabe, J. Mao, J. Pérez-Losada, 2022, Cancers.

Role of the Grb2-Associated Binder 1/SHP-2 Interaction in Cell Growth and Transformation

A. Wong, M. Holgado-Madruga, Marina Holgado-Madruga, 2004, Cancer Research.

Determination of Gab1 (Grb2-associated binder-1) interaction with insulin receptor-signaling molecules.

E. Van Obberghen, S. Rocchi, J. Murdaca, 1998, Molecular endocrinology.

c-Jun NH(2)-terminal kinase 2alpha2 promotes the tumorigenicity of human glioblastoma cells.

Shuang-yin Han, J. Cui, A. Wong, 2006, Cancer research.

Targeting a glioblastoma cancer stem-cell population defined by EGF receptor variant III.

K. Jensen, H. Vogel, Shuang-yin Han, 2014, Cancer Research.

Proteolytic cleavage of the CD44 adhesion molecule in multiple human tumors.

A. Godwin, H. Saya, A. Guha, 2002, The American journal of pathology.

Evolutionary Origins of Metabolic Reprogramming in Cancer

M. Mendiburu-Eliçabe, J. Mao, J. Pérez-Losada, 2022, International journal of molecular sciences.

Identification of a Specific Domain Responsible for JNK2α2 Autophosphorylation*

P. Wedegaertner, J. Cui, A. Wong, 2005, Journal of Biological Chemistry.

Identification of a specific domain responsible for JNK2alpha2 autophosphorylation.

P. Wedegaertner, J. Cui, A. Wong, 2005, The Journal of biological chemistry.

Host adaptor proteins Gab1 and CrkII promote InlB‐dependent entry of Listeria monocytogenes

Hong Sun, Yang Shen, K. Ireton, 2005, Cellular microbiology.

Development of an EGFRvIII specific recombinant antibody

Shuang-yin Han, S. Mitra, Gordon Li, 2010, BMC biotechnology.