Simon Glerup

发表

Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling

J. Nyengaard, C. Vaegter, L. Tessarollo, 2011, Nature Neuroscience.

Exploring the sortilin related receptor, SorLA, in depression.

O. Mors, B. Elfving, H. Buttenschøn, 2018, Journal of affective disorders.

Biochemical and cognitive effects of docosahexaenoic acid differ in a developmental and SorLA dependent manner

J. Nyengaard, J. Lykkesfeldt, A. Nykjær, 2018, Behavioural Brain Research.

Reduced Alcohol Seeking and Withdrawal Symptoms in Mice Lacking the BDNF Receptor SorCS2

S. Østergaard, A. Nykjær, M. Kjolby, 2019, Front. Pharmacol..

Brain volumetric alterations accompanied with loss of striatal medium-sized spiny neurons and cortical parvalbumin expressing interneurons in Brd1+/− mice

S. Eskildsen, J. Nyengaard, O. Mors, 2018, Scientific Reports.

Cognitive deficits caused by a disease-mutation in the α3 Na+/K+-ATPase isoform

J. Nyengaard, E. Füchtbauer, P. Nissen, 2016, Scientific Reports.

Targeting PCSK9 to tackle cardiovascular disease.

C. Gustafsen, J. Vilstrup, S. Glerup, 2023, Pharmacology & therapeutics.

PCSK9 deficiency alters brain lipid composition without affecting brain development and function

V. Tarabykin, P. Madsen, T. Timmusk, 2023, Frontiers in Molecular Neuroscience.

Layers II/III of Prefrontal Cortex in Df(h22q11)/+ Mouse Model of the 22q11.2 Deletion Display Loss of Parvalbumin Interneurons and Modulation of Neuronal Morphology and Excitability

S. Okujeni, J. Nyengaard, C. Sánchez, 2020, Molecular Neurobiology.

C. Vaegter, T. Willnow, A. Nykjaer, 2013, PloS one.

Investigation of serum levels of sortilin in response to antidepressant treatment

O. Mors, H. Buttenschøn, S. Glerup, 2017, Acta Neuropsychiatrica.

Increased serum levels of sortilin are associated with depression and correlated with BDNF and VEGF

O. Mors, A. Børglum, D. Demontis, 2015, Translational Psychiatry.

Df(h22q11)/+ mouse model exhibits reduced binding levels of GABAA receptors and structural and functional dysregulation in the inhibitory and excitatory networks of hippocampus

J. Nyengaard, A. Landau, A. R. Khan, 2022, Molecular and Cellular Neuroscience.

Formation of high-molecular-weight angiotensinogen during pregnancy is a result of competing redox reactions with the proform of eosinophil major basic protein.

M. Christiansen, C. Oxvig, K. Pihl, 2013, The Biochemical journal.

Altered dopaminergic firing pattern and novelty response underlie ADHD-like behavior of SorCS2-deficient mice

M. Didriksen, Inge E. M. de Jong, A. Nykjaer, 2021, Translational Psychiatry.

SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRα1 and RET.

J. Nyengaard, M. Saarma, C. Vaegter, 2013, Cell reports.

SorLA regulates the activity of lipoprotein lipase by intracellular trafficking

M. Nyegaard, O. Bakke, G. Olivecrona, 2011 .

Sortilin Modulates Schwann Cell Signaling and Remak Bundle Regeneration Following Nerve Injury

Simone Hjæresen, S. Mohseni, O. Andersen, 2022, Frontiers in Cellular Neuroscience.

Loss of BDNF or its receptors in three mouse models has unpredictable consequences for anxiety and fear acquisition.

A. Nykjaer, Ditte Olsen, M. Kaas, 2013, Learning & memory.

Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model

M. Lauritzen, E. Füchtbauer, P. Nissen, 2016, Scientific Reports.

Sortilins in neurotrophic factor signaling.

C. Vaegter, A. Nykjaer, S. Glerup, 2014, Handbook of experimental pharmacology.

Identification of a Linear Epitope in Sortilin That Partakes in Pro-neurotrophin Binding*

P. Boisguérin, R. Volkmer, T. Willnow, 2010, The Journal of Biological Chemistry.

Physiological and therapeutic regulation of PCSK9 activity in cardiovascular disease

U. Laufs, R. Schulz, K. Schlüter, 2017, Basic Research in Cardiology.

Placental Regulation of Peptide Hormone and Growth Factor Activity by proMBP1

S. Glerup, K. Weyer, Simon Glerup, 2011, Biology of reproduction.

Cell Surface Detachment of Pregnancy-associated Plasma Protein-A Requires the Formation of Intermolecular Proteinase-Inhibitor Disulfide Bonds and Glycosaminoglycan Covalently Bound to the Inhibitor*

S. Thiel, C. Conover, C. Oxvig, 2007, Journal of Biological Chemistry.

The Proform of the Eosinophil Major Basic Protein Binds the Cell Surface through a Site Distinct from Its C-type Lectin Ligand-binding Region*

C. Oxvig, S. Glerup, S. Kløverpris, 2006, Journal of Biological Chemistry.

Proteinase Inhibition by Proform of Eosinophil Major Basic Protein (pro-MBP) Is a Multistep Process of Intra- and Intermolecular Disulfide Rearrangements*

L. Giudice, M. Overgaard, C. Oxvig, 2005, Journal of Biological Chemistry.

Inhibition of proteolysis by the proform of eosinophil major basic protein (proMBP) requires covalent binding to its target proteinase

L. Giudice, M. Overgaard, M. Christiansen, 2004, FEBS letters.

Spatiotemporal patterns of sortilin and SorCS2 localization during organ development

J. Nyengaard, S. Molgaard, S. Glerup, 2016, BMC Cell Biology.

Alternative splicing regulates adaptor protein binding, trafficking, and activity of the Vps10p domain receptor SorCS2 in neuronal development

P. Madsen, H. Buttenschøn, Perline A. Demange, 2023, The Journal of biological chemistry.

Soluble sortilin is present in excess and positively correlates with progranulin in CSF of aging individuals

R. Petersen, D. Demontis, N. Finch, 2016, Experimental Gerontology.

Df(h15q13)/+ Mouse Model Reveals Loss of Astrocytes and Synaptic-Related Changes of the Excitatory and Inhibitory Circuits in the Medial Prefrontal Cortex.

J. Nyengaard, C. Sánchez, P. Qvist, 2020, Cerebral cortex.

SorCS2 is required for BDNF-dependent plasticity in the hippocampus

J. Nyengaard, C. Vaegter, L. Pedersen, 2016, Molecular Psychiatry.

SorCS2 Regulates Dopaminergic Wiring and Is Processed into an Apoptotic Two-Chain Receptor in Peripheral Glia

G. Eichele, J. Nyengaard, E. Füchtbauer, 2014, Neuron.

The hypercholesterolemia-risk gene SORT1 facilitates PCSK9 secretion.

O. Mors, M. Nyegaard, M. Mattheisen, 2014, Cell metabolism.

Proprotein convertase subtilisin/kexin type 9 targets megalin in the kidney proximal tubule and aggravates proteinuria in nephrotic syndrome.

P. Madsen, P. Ivarsen, H. Birn, 2023, Kidney international.

APOE4-mediated amyloid-&bgr; pathology depends on its neuronal receptor LRP1

M. Murray, D. Dickson, G. Bu, 2019, The Journal of clinical investigation.

Highly segregated localization of the functionally related vps10p receptors sortilin and SorCS2 during neurodevelopment

J. Nyengaard, S. Molgaard, S. Glerup, 2018, The Journal of comparative neurology.

Risk Locus Identification Ties Alcohol Withdrawal Symptoms to SORCS2

Hongyu Zhao, L. Farrer, D. Goldman, 2018, Alcoholism, clinical and experimental research.

APOE 4-mediated amyloid-b pathology depends on its neuronal receptor LRP 1

M. Murray, D. Dickson, G. Bu, 2019 .

Progranulin gene variation affects serum progranulin levels differently in Danish bipolar individuals compared with healthy controls

O. Mors, H. Buttenschøn, A. Nykjær, 2017, Psychiatric genetics.

Sortilin and SorLA Display Distinct Roles in Processing and Trafficking of Amyloid Precursor Protein

P. Madsen, O. Andersen, A. Nykjær, 2013, The Journal of Neuroscience.

Temporal course of pregnancy-associated plasma protein-A in angioplasty-treated ST-elevation myocardial infarction patients and potential significance of concomitant heparin administration.

C. Terkelsen, E. Falk, H. Møller, 2009, The American journal of cardiology.

Immunofluorescent visualization of mouse interneuron subtypes

J. Nyengaard, C. Vaegter, S. Molgaard, 2014, F1000Research.