Miguel R. Lugo

发表

Molecular dynamics and in silico mutagenesis on the reversible inhibitor-bound SARS-CoV-2 main protease complexes reveal the role of lateral pocket in enhancing the ligand affinity

A. Ganesan, M. R. Lugo, S. Kalyaanamoorthy, 2020, Scientific Reports.

Diacylglycerol regulates the plasma membrane calcium pump from human erythrocytes by direct interaction.

M. R. Lugo, G. Benaim, M. C. Pérez-Gordones, 2009, Archives of biochemistry and biophysics.

Dynamics of Scabin toxin. A proposal for the binding mode of the DNA substrate

Derek J. Wilson, M. R. Lugo, A. R. Merrill, 2018, PloS one.

Structural variability of C3larvin toxin. Intrinsic dynamics of the α/β fold of the C3-like group of mono-ADP-ribosyltransferase toxins

M. R. Lugo, A. R. Merrill, D. Dutta, 2016, Journal of biomolecular structure & dynamics.

Membrane topology of the colicin E1 channel using genetically encoded fluorescence.

A. Lomize, I. Pogozheva, Derek Ho, 2011, Biochemistry.

Characterization of C3larvinA, a novel RhoA-targeting ADP-ribosyltransferase toxin produced by the honey bee pathogen, Paenibacillus larvae

E. Genersch, M. R. Lugo, Madison Turner, 2019, Bioscience reports.

New Insights into the Drug Binding, Transport and Lipid Flippase Activities of the P-Glycoprotein Multidrug Transporter

M. R. Lugo, F. Sharom, Paul D. W. Eckford, 2005, Journal of bioenergetics and biomembranes.

Interaction of LDS-751 and rhodamine 123 with P-glycoprotein: evidence for simultaneous binding of both drugs.

M. R. Lugo, F. Sharom, Frances J Sharom, 2005, Biochemistry.

Scabin, a Novel DNA-acting ADP-ribosyltransferase from Streptomyces scabies*

M. R. Lugo, A. R. Merrill, D. Dutta, 2016, The Journal of Biological Chemistry.

Development of Anti-Virulence Therapeutics against Mono-ADP-Ribosyltransferase Toxins

M. R. Lugo, A. R. Merrill, Miguel R. Lugo, 2020, Toxins.

Characterization of Vis Toxin, a Novel ADP-Ribosyltransferase from Vibrio splendidus.

E. Pai, R. Fieldhouse, M. R. Lugo, 2015, Biochemistry.

A comparative structure‐function analysis of active‐site inhibitors of Vibrio cholerae cholix toxin

M. R. Lugo, A. R. Merrill, Miguel R. Lugo, 2015, Journal of molecular recognition : JMR.

The Father, Son and Cholix Toxin: The Third Member of the DT Group Mono-ADP-Ribosyltransferase Toxin Family

M. R. Lugo, A. R. Merrill, Miguel R. Lugo, 2015, Toxins.

Pocket analysis of the full-length cholix toxin. An assessment of the structure–dynamics of the apo catalytic domain

M. R. Lugo, A. R. Merrill, Miguel R. Lugo, 2015, Journal of biomolecular structure & dynamics.

C3larvin Toxin, an ADP-ribosyltransferase from Paenibacillus larvae*

D. Krska, R. Ravulapalli, A. Merrill, 2014, The Journal of Biological Chemistry.

Resolving the 3D spatial orientation of helix I in the closed state of the colicin E1 channel domain by FRET. Insights into the integration mechanism.

Derek Ho, M. R. Lugo, A. R. Merrill, 2016, Archives of biochemistry and biophysics.

The 1.8 Å Cholix Toxin Crystal Structure in Complex with NAD+ and Evidence for a New Kinetic Model

R. Fieldhouse, M. R. Lugo, A. R. Merrill, 2012, The Journal of Biological Chemistry.

Interaction of LDS-751 with the drug-binding site of P-glycoprotein: a Trp fluorescence steady-state and lifetime study.

M. R. Lugo, F. Sharom, Frances J Sharom, 2009, Archives of biochemistry and biophysics.

Interaction of LDS-751 with P-glycoprotein and mapping of the location of the R drug binding site.

M. R. Lugo, F. Sharom, Miguel R. Lugo, 2005, Biochemistry.